There are 4 ways to get from Santiago to St. Louis by plane, car, bus, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Lambert–St. Louis International Airport
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Lambert–St. Louis International Airport (STL)plane SCL - STL
14h 23m$365–1,405Fly to Barkley Regional Airport, drive
cheapest- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Barkley Regional Airport (PAH)plane SCL - PAH
- Drive from Barkley Regional Airport (PAH) to St. Louiscar
21h 28m$292–1,052Fly to Evansville, bus
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Evansville (EVV)plane SCL - EVV
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus
20h 38m$298–1,022Fly to Columbia Regional Airport, shuttle
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Columbia Regional Airport (COU)plane SCL - COU
- Take a shuttle bus from Jefferson City, Missouri to St Louis International Airport
20h 5m$500–1,265
Comodoro Arturo Merino Benítez International Airport (SCL) to Lambert–St. Louis International Airport (STL) flights
Comparing Your Travel Options
The cheapest way to get from Santiago to St. Louis is to fly and bus which costs $290 - $1,100 and takes 20h 38m.
The fastest way to get from Santiago to St. Louis is to fly which takes 14h 23m and costs $360 - $1,500.
The distance between Santiago and St. Louis is 5193 miles.
It takes approximately 14h 23m to get from Santiago to St. Louis, including transfers.
St. Louis is 2h behind Santiago. It is currently 3:20 AM in Santiago and 1:20 AM in St. Louis.
There are 559+ hotels available in St. Louis.
What companies run services between Santiago, Chile and St. Louis, MO, USA?
American Airlines, Delta, and four other airlines fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Lambert–St. Louis International Airport (STL) 5 times a day.
- Website
- united.com
Flights from Comodoro Arturo Merino Benítez International Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 13h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $370–1,400
Flights from Comodoro Arturo Merino Benítez International Airport to Barkley Regional Airport via Houston
- Ave. Duration
- 22h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $260–1,000
Flights from Comodoro Arturo Merino Benítez International Airport to Barkley Regional Airport via Panama City, Houston
- Ave. Duration
- 16h 29m
- When
- Every day
- Estimated price
- $270–1,000
Flights from Comodoro Arturo Merino Benítez International Airport to Barkley Regional Airport via Atlanta, Chicago O'Hare
- Ave. Duration
- 17h 42m
- When
- Every day
- Estimated price
- $280–1,100
Flights from Comodoro Arturo Merino Benítez International Airport to Barkley Regional Airport via Medellin Jose Marie Cordova, Houston
- Ave. Duration
- 18h 54m
- When
- Monday, Tuesday, Friday, and Saturday
- Estimated price
- $420–1,100
Flights from Comodoro Arturo Merino Benítez International Airport to Barkley Regional Airport via Mexico City, Houston
- Ave. Duration
- 20h 40m
- When
- Saturday and Sunday
- Estimated price
- $270–1,100
Flights from Comodoro Arturo Merino Benítez International Airport to Barkley Regional Airport via Dallas/Ft.Worth, Houston
- Ave. Duration
- 21h 20m
- When
- Every day
- Estimated price
- $290–1,100
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $26–45
- Website
- Greyhound
Want to know more about travelling around United States
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