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How to get fromSantiago to Tupizaby plane, bus, car, shuttle, or train

Find Transport to Tupiza

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There are 8 ways to get from Santiago to Tupiza by plane, bus, car, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tarija, bus

    best
    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Tarija (TJA)plane plane SCL - TJA
    2. Take the bus from Tarija to Tupizabus bus
    12h 34m
    $388–724

  2. Bus

    cheapest
    1. Take the bus from Terminal Alameda - Turbus to Terminal Rodoviario Calamabus bus
    2. Take the bus from Terminal Rodoviario Calama to Uyunibus bus
    3. Take the bus from Uyuni to Tupizabus bus
    34h 43m
    $69–119

  3. Drive 1,977.7 km

    1. Drive from Santiago to Tupizacar car 1,977.7 km
    25h 4m
    $244–353

  4. Fly to Uyuni Airport, bus

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Uyuni Airport (UYU)plane plane SCL - UYU
    2. Take the bus from Uyuni to Tupizabus bus
    15h 42m
    $393–815

  5. Fly to Calama Airport, shuttle, Tour, bus

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Calama Airport (CJC)plane plane SCL - CJC
    2. Take a shuttle bus from Calama Airport to San Pedro de Atacamashuttle bus
    3. Take a shuttle bus from San Pedro de Atacama to Uyunishuttle bus
    4. Take the bus from Uyuni to Tupizabus bus
    14h 2m
    $447–567

  6. Fly to Gobernador Horacio Guzmán International Airport, bus

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Gobernador Horacio Guzmán International Airport (JUJ)plane plane SCL - JUJ
    2. Take the bus from San Salvador de Jujuy to Terminal La Quiacabus bus
    3. Take the bus from Villazón to Tupizabus bus
    17h 53m

  7. Bus, train via Calama

    1. Take the bus from Santiago to Calamabus bus
    2. Take the bus from Terminal Rodoviario Calama to Uyunibus bus
    3. Take the train from Uyuní to Tupizatrain train
    38h 3m
    $195–306

  8. Bus, train

    1. Take the bus from Terminal Sur de Santiago to Terminal Mendozabus bus
    2. Take the bus from Terminal Mendoza to Terminal La Quiacabus bus
    3. Take the train from Villazón to Tupizatrain train
    40h 24m
    $87–174

Santiago to Tupiza by bus, car, and train

Calendar1Weekly Services
Duration40h 24mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Santiago to Tupiza.ExpandLaunch map view
  • Distance: 1,674.4 km
  • Duration: 12h 34m

What companies run services between Santiago, Chile and Tupiza, Bolivia?

You can take a subway from Pajaritos Dirección Los Domínicos to Tupiza via Universidad de Santiago Dirección Los Domínicos, Terminal Alameda - Turbus, Terminal Rodoviario Calama, and Uyuni in around 34h 43m.

Airlines
Train operators
Bus operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Heading to Europe? Read this before you buy a Eurail Pass, How to get from London to Edinburgh, and How to travel India's Golden Triangle - to help you get the most out of your next trip.