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How to get fromSanto Domingo, Ecuador to Cuencaby bus, plane, or car

Find Transport to Cuenca

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There are 6 ways to get from Santo Domingo, Ecuador to Cuenca by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly

    best
    1. Take the bus from Santo Domingo de los Colorados to Quito Terminal Carcelénbus bus
    2. Fly from Mariscal Sucre International Airport (UIO) to Cuenca (CUE)plane plane UIO - CUE
    4h 24m
    $99–231

  2. Bus via Guayaquil Airport (GYE)

    cheapest
    1. Take the bus from Santo Domingo de los Colorados to Terminal Terrestre de Guayaquilbus bus Guayaquil / ...
    2. Take the bus from Terminal Terrestre de Guayaquil to Cuencabus bus Guayaquil / ...
    8h 39m
    $14–54

  3. Bus

    1. Take the bus from Santo Domingo de los Colorados to Alóagbus bus
    2. Take the bus from Alóag to Ambatobus bus
    3. Take the bus from Ambato to Cuencabus bus
    8h 3m
    $16–34

  4. Drive 420.8 km

    1. Drive from Santo Domingo, Ecuador to Cuencacar car 420.8 km
    6h 43m
    $24–35

  5. Bus via Puyo

    1. Take the bus from Santo Domingo de los Tsachilas to Puyobus bus
    2. Take the bus from Puyo to Guarumalesbus bus
    3. Take the bus from Guarumales to Cuencabus bus
    8h 12m
    $29–43

  6. Bus #2

    1. Take the bus from Santo Domingo de los Colorados to Riobambabus bus Santo Domingo de los Colorados
    2. Take the bus from Riobamba to Cuencabus bus Riobamba
    12h 5m
    $17–38

Mariscal Sucre International Airport (UIO) to Cuenca (CUE) flights

Calendar38Weekly Planes
Duration1h 11mAverage Duration
Ticket$90Cheapest Price
See schedules

Questions & Answers

Map of how to get from Santo Domingo, Ecuador to Cuenca.ExpandLaunch map view
  • Distance: 508 km
  • Duration: 4h 24m

What companies run services between Santo Domingo, Ecuador and Cuenca, Ecuador?

You can take a bus from Santo Domingo de los Colorados to Cuenca via Alóag and Ambato in around 8h 3m.

Airlines
Bus operators

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