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How to get fromSanto Domingo de los Colorados to Guayaquilby bus, car, taxi, or plane

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There are 4 ways to get from Santo Domingo de los Colorados to Guayaquil by bus, car, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Santo Domingo de los Colorados to Terminal Terrestre de Guayaquilbus bus Guayaquil / ...
    4h 53m
    $6–21

  2. Drive 268.8 km

    1. Drive from Santo Domingo de los Colorados to Guayaquilcar car 268.8 km
    4h 12m
    $16–22

  3. Taxi

    1. Take the taxi from Santo Domingo de los Colorados to Guayaquiltaxi taxi 268.8 km
    4h 12m
    $150–180

  4. Bus, fly

    1. Take the bus from Santo Domingo de los Colorados to Quito Terminal Carcelénbus bus
    2. Fly from Mariscal Sucre International Airport (UIO) to José Joaquín De Olmedo International Airport (GYE)plane plane UIO - GYE
    3h 48m
    $94–141

Mariscal Sucre International Airport (UIO) to José Joaquín De Olmedo International Airport (GYE) flights

Calendar113Weekly Planes
Duration54 minAverage Duration
Ticket$32Cheapest Price
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Questions & Answers

Map of how to get from Santo Domingo de los Colorados to Guayaquil.ExpandLaunch map view
  • Distance: 268.3 km
  • Duration: 4h 53m

What companies run services between Santo Domingo de los Colorados, Ecuador and Guayaquil, Ecuador?

Trans Esmeraldas S.A. operates a bus from Santo Domingo de los Colorados to Terminal Terrestre de Guayaquil every 30 minutes. Tickets cost $12–19 and the journey takes 4h 53m. Seven other operators also service this route.

Airlines
Bus operators
Other operators

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