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How to get fromSanto Domingo to Mayagüezby plane, car ferry, car, or shuttle

Find Transport to Mayagüez

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There are 7 ways to get from Santo Domingo to Mayagüez by plane, car ferry, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Las Américas International Airport to Eugenio María De Hostos Airport

    best
    1. Fly from Las Américas International Airport (SDQ) to Eugenio María De Hostos Airport (MAZ)plane plane SDQ - MAZ
    5h 51m
    $271–682

  2. Car ferry, drive

    cheapest
    1. Take the carferry from Santo Domingo to Old San Juancarferry car ferry Santo Domingo
    2. Drive from Old San Juan to Mayagüezcar car
    15h 10m
    $81–90

  3. Shuttle to Punta Cana International Airport, fly to Eugenio María De Hostos Airport

    1. Take a shuttle bus from Santo Domingo to Punta Cana Airportshuttle bus
    2. Fly from Punta Cana International Airport (PUJ) to Eugenio María De Hostos Airport (MAZ)plane plane PUJ - MAZ
    6h 54m
    $356–1,347

  4. Fly Las Américas International Airport to Luis Munoz Marin International Airport, shuttle, drive

    1. Fly from Las Américas International Airport (SDQ) to Luis Munoz Marin International Airport (SJU)plane plane SDQ - SJU
    2. Take a shuttle bus from San Juan Airport to Hilton Ponce Golf & Casino Resortshuttle bus
    3. Drive from Hilton Ponce Golf & Casino Resort to Mayagüezcar car
    7h 13m
    $298–813

  5. Shuttle to Punta Cana International Airport, fly to Luis Munoz Marin International Airport, shuttle, drive

    1. Take a shuttle bus from Santo Domingo to Punta Cana Airportshuttle bus
    2. Fly from Punta Cana International Airport (PUJ) to Luis Munoz Marin International Airport (SJU)plane plane PUJ - SJU
    3. Take a shuttle bus from San Juan Airport to Hilton Ponce Golf & Casino Resortshuttle bus
    4. Drive from Hilton Ponce Golf & Casino Resort to Mayagüezcar car
    7h 34m
    $398–1,078

  6. Car ferry, shuttle, drive

    1. Take the carferry from Santo Domingo to Old San Juancarferry car ferry
    2. Take a shuttle bus from San Juan Airport to Hyatt Hacienda del Marshuttle bus
    3. Drive from Hyatt Hacienda del Mar to Mayagüezcar car
    17h 4m
    $213–280

  7. Car ferry, shuttle, drive via Ponce

    1. Take the carferry from Santo Domingo to Old San Juancarferry car ferry
    2. Take a shuttle bus from San Juan Airport to Hilton Ponce Golf & Casino Resortshuttle bus
    3. Drive from Hilton Ponce Golf & Casino Resort to Mayagüezcar car
    17h 31m
    $278–373

Las Américas International Airport (SDQ) to Eugenio María De Hostos Airport (MAZ) flights

Calendar11Weekly Planes
Duration3h 29mAverage Duration
Ticket$31Cheapest Price
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Questions & Answers

Map of how to get from Santo Domingo to Mayagüez.ExpandLaunch map view
  • Distance: 303.1 km
  • Duration: 5h 51m

What companies run services between Santo Domingo, Dominican Republic and Mayagüez, Puerto Rico?

JetBlue Airways, Cape Air, and two other airlines fly from Las Américas International Airport (SDQ) to Eugenio María De Hostos Airport (MAZ) twice daily.

Airlines
Bus operators
Ferry operators

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