How to get fromSanto Domingo to Santiagoby plane, shuttle, or bus

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There are 4 ways to get from Santo Domingo to Santiago by plane, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from Las Américas International Airport
best
1. Fly from Las Américas International Airport (SDQ) to Comodoro Arturo Merino Benítez International Airport (SCL)plane SDQ - SCL
12h 47m
$401–633
Shuttle to Punta Cana International Airport, fly
1. Take a shuttle bus from Santo Domingo to Punta Cana Airportshuttle
2. Fly from Punta Cana International Airport (PUJ) to Comodoro Arturo Merino Benítez International Airport (SCL)plane PUJ - SCL
11h 57m
$416–588
Fly from Dr. Joaquin Balaguer Airport
1. Fly from Dr. Joaquin Balaguer Airport (JBQ) to Comodoro Arturo Merino Benítez International Airport (SCL)plane JBQ - SCL
16h 31m
$440–1,326
Bus to Cibao International Airport, fly
1. Take the bus from Santo Domingo to La Vegabus
2. Fly from Cibao International Airport (STI) to Comodoro Arturo Merino Benítez International Airport (SCL)plane STI - SCL
14h 49m
$524–1,859

Las Américas International Airport (SDQ) to Comodoro Arturo Merino Benítez International Airport (SCL) flights

39Weekly Planes

10h 38mAverage Duration

$264Cheapest Price

Questions & Answers

Map of how to get from Santo Domingo to Santiago.

Launch map view

Distance: 5,804 km
Duration: 12h 47m

What companies run services between Santo Domingo, Dominican Republic and Santiago, Chile?

Avianca - Aerovías del Continente Americano S.A. and Copa Airlines fly from Las Américas International Airport (SDQ) to Comodoro Arturo Merino Benítez International Airport (SCL) every 4 hours.

Airlines

Bus operators

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Santiago(opens in a new window), Chile(opens in a new window)

Santiago, also known as Santiago de Chile, is the capital and largest city of Chile and one of the largest cities in the Americas. It is located in the country's central valley and is the center of the Santiago Metropolitan Region, which has a population of 7 million, representing 40% of Chile's total population. Most of the city is situated between above sea level.

Things to do in Santiago

Fantasilandia(Opens in a new window)

Fantasilandia is a Chilean amusement park. The park opened in 1978 and is located in a corner of O'Higgins Park in Santiago, Chile.

Places to stay in Santiago

Hotel Plaza San Francisco(Opens in a new window)

8.9Fabulous

Hotel Cumbres Lastarria(Opens in a new window)

9.0Fabulous

Hotel Luciano K(Opens in a new window)

8.6Fabulous

Plaza Huelen(Opens in a new window)

9.3Superb

Rome2Rio makes travelling from Santo Domingo to Santiago easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Santo Domingo to Santiago right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.