There are 7 ways to get from Sarasota to Santee by plane, car, bus, taxi, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Sarasota–Bradenton International Airport to Columbia, drive
best- Fly from Sarasota–Bradenton International Airport (SRQ) to Columbia (CAE)plane SRQ - CAE
- Drive from Columbia-Airport-CAE to Santeecar
6h 4m$240–1,318Drive 479.2 mi
cheapest- Drive from Sarasota to Santeecar 479.2 mi
8h 15m$88–127Bus, taxi
- Take the bus from Bradenton/Sarasota - Mobil Gas Station to University of South Florida - 3801 USF Holly Drbus
- Take the bus from University of South Florida to Gainesvillebus
- Take the bus from Gainesville to Jacksonvillebus
- Take the bus from Jacksonville to Walterboro, SCbus
- Take the taxi from Walterboro, SC to Santeetaxi
13h 14m$176–270Bus, train, drive
- Take the bus from Sarasota Cattlemen Transfer Center to Tampa Bus Stationbus
- Take the train from Tampa to Kissimmee Amtrak Stationtrain
- Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain
- Drive from Charleston Amtrak Station to Santeecar
15h 51m$178–370Bus to Tampa, fly to Charleston International Airport, drive
- Take the bus from Sarasota Cattlemen Transfer Center to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Charleston International Airport (CHS)plane TPA - CHS
- Drive from Charleston-Airport-CHS to Santeecar
7h 28m$164–378Bus (Flixbus)
- Take the bus from Sarasota Cattlemen Transfer Center to Orlando Bus Stationbus FlixBus 2421
- Take the bus from Orlando Bus Station to Orangeburgbus FlixBus 2433
13h 30m$166–252Amtrak Thruway, train, bus
- Take the bus from Sarasota Amtrak Bus Stop to Orlando, FLbus
- Take the train from Orlando to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Orangeburgbus
16h 56m$262–466
Sarasota–Bradenton International Airport (SRQ) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Sarasota to Santee is to drive which costs $85 - $130 and takes 8h 15m.
The fastest way to get from Sarasota to Santee is to fly and drive which takes 6h 4m and costs $240 - $1,400.
No, there is no direct bus from Sarasota to Santee. However, there are services departing from Fruitville Rd @ N Jefferson Ave and arriving at Orangeburg via Sarasota Cattlemen Transfer Center and Orlando Bus Station. The journey, including transfers, takes approximately 13h 30m.
The distance between Sarasota and Santee is 529 miles. The road distance is 482 miles.
The best way to get from Sarasota to Santee without a car is to bus and taxi which takes 13h 14m and costs $170 - $270.
It takes approximately 6h 4m to get from Sarasota to Santee, including transfers.
Sarasota to Santee bus services, operated by Flixbus USA, depart from Sarasota Cattlemen Transfer Center station.
Sarasota to Santee bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Sarasota to Santee is 482 miles. It takes approximately 8h 15m to drive from Sarasota to Santee.
There are 41+ hotels available in Santee.
What companies run services between Sarasota, FL, USA and Santee, SC, USA?
You can take a bus from Fruitville Rd @ N Jefferson Ave to Santee via Cattlemen Transit Station, Sarasota Cattlemen Transfer Center, Orlando Bus Station, and Orangeburg in around 13h 30m.
- Website
- delta.com
Flights from Sarasota–Bradenton International Airport to Columbia via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Tampa to Charleston International Airport via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $80–420
- Website
- aa.com
Flights from Sarasota–Bradenton International Airport to Columbia via Charlotte
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Sarasota–Bradenton International Airport to Columbia via Philadelphia
- Ave. Duration
- 5h 48m
- When
- Friday
- Estimated price
- $410–1,800
Flights from Tampa to Charleston International Airport via Miami
- Ave. Duration
- 3h 57m
- When
- Tuesday
- Estimated price
- $80–420
- Website
- flybreeze.com
Flights from Tampa to Charleston International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $140–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tampa to Kissimmee Amtrak Station
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $23–50
- Website
- https://www.amtrak.com/home.html
Train from Kissimmee Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 8h 28m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- https://www.amtrak.com/home.html
Train from Orlando to Charleston Amtrak Station
- Ave. Duration
- 7h 49m
- Frequency
- Once daily
- Estimated price
- $120–270
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Bradenton/Sarasota - Mobil Gas Station to University of South Florida - 3801 USF Holly Dr
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $15–29
- Website
- https://www.redcoachusa.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from University of South Florida to Gainesville
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a week
- Estimated price
- $11–19
- Schedules at
- flixbus.com
Bus from Sarasota Cattlemen Transfer Center to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $10–18
- Schedules at
- flixbus.com
Bus from Sarasota Cattlemen Transfer Center to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $10–18
- Schedules at
- flixbus.com
Bus from Sarasota Cattlemen Transfer Center to Orlando Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $24–40
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Orangeburg
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Jacksonville to Walterboro, SC
- Ave. Duration
- 3h 49m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Orangeburg
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $10–20
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Sarasota Amtrak Bus Stop to Orlando, FL
- Ave. Duration
- 4h 10m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Website
- https://www.amtrak.com/home.html
- Ave. Duration
- 31 min
- Estimated price
- $100–120
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