There are 8 ways to get from Sarnia to Knoxville by car, car ferry, train, plane, bus, bus (Flixbus), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, car ferry, train to Bishop International Airport, fly
best- Drive from Sarnia to Walpole Island, ONcar
- Take the carferry from Walpole Island, ON to Algonac, MIcarferry
- Drive from Algonac, MI to Port Huron Stationcar
- Take the train from Port Huron Station to Flint Amtrak Stationtrain
- Fly from Bishop International Airport (FNT) to Mcghee Tyson Airport (TYS)plane FNT - TYS
10h 24m$275–1,082Drive 572.1 mi
cheapest- Drive from Sarnia to Knoxvillecar 572.1 mi
9h 40m$131–190Train, bus via London
- Take the train from Sarnia to Londontrain
- Take the train from London to Aldershottrain
- Take the train from Aldershot to New York Penn Stationtrain
- Take the bus from New York, NY to Knoxville, TNbus Ny
30h 33m$305–782Bus
- Take the bus from Sarnia to Toronto Pearson Airportbus
- Take the bus from Toronto Pearson Airport to New York Midtownbus
- Take the bus from New York to Knoxvillebus Nyc
30h 56m$286–414Drive, car ferry, train, bus to Mbs International Airport, fly
- Drive from Sarnia to Walpole Island, ONcar
- Take the carferry from Walpole Island, ON to Algonac, MIcarferry
- Drive from Algonac, MI to Port Huron Stationcar
- Take the train from Port Huron Station to Flint Amtrak Stationtrain
- Take the bus from Flint Amtrak to Saginaw Bus Centerbus
- Fly from Mbs International Airport (MBS) to Mcghee Tyson Airport (TYS)plane MBS - TYS
10h 47m$249–985Drive, car ferry, train, bus to Detroit, fly
- Drive from Sarnia to Walpole Island, ONcar
- Take the carferry from Walpole Island, ON to Algonac, MIcarferry
- Drive from Algonac, MI to Port Huron Stationcar
- Take the train from Port Huron Station to Flint Amtrak Stationtrain
- Take the bus from Flint Amtrak to Detroit Greyhoundbus
- Fly from Detroit (DTW) to Mcghee Tyson Airport (TYS)plane DTW - TYS
11h 2m$266–1,168Bus via London
- Take the bus from Sarnia, ON - Bayside Terminal to London, ON - Downtownbus
- Take the bus from London, ON - VIA Rail to Toronto, ON - 44 York St.bus
- Take the bus from Toronto to Port Authority Bus Terminalbus
- Take the bus from New York to Knoxvillebus Nyc
31h 51m$295–428Train, bus
- Take the train from Sarnia to Toronto Union Stationtrain
- Take the train from Toronto Union Station to New York Penn Stationtrain
- Take the bus from New York to Knoxvillebus Nyc
32h 25m$371–773
Bishop International Airport (FNT) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Sarnia to Knoxville is to drive which costs $130 - $190 and takes 9h 40m.
The fastest way to get from Sarnia to Knoxville is to drive which takes 9h 40m and costs $130 - $190.
No, there is no direct bus from Sarnia to Knoxville. However, there are services departing from Sarnia and arriving at Knoxville via Toronto Pearson Airport and New York. The journey, including transfers, takes approximately 30h 56m.
The distance between Sarnia and Knoxville is 640 miles. The road distance is 575.4 miles.
The best way to get from Sarnia to Knoxville without a car is to train and bus via London which takes 30h 33m and costs $300 - $800.
It takes approximately 10h 24m to get from Sarnia to Knoxville, including transfers.
Sarnia to Knoxville bus services, operated by Flixbus USA, depart from Sarnia station.
Sarnia to Knoxville bus services, operated by Flixbus USA, arrive at Toronto Pearson Airport station.
Yes, the driving distance between Sarnia to Knoxville is 575 miles. It takes approximately 9h 40m to drive from Sarnia to Knoxville.
There are 326+ hotels available in Knoxville.
What companies run services between Sarnia, ON, Canada and Knoxville, TN, USA?
You can take a bus from Sarnia to Knoxville via Toronto Pearson Airport, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 30h 56m.
- Website
- delta.com
Flights from Mbs International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $130–800
Flights from Detroit to Mcghee Tyson Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $160–1,000
Flights from Detroit to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $15–40
- Website
- Amtrak
Train from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $15–40
- Website
- Amtrak
Train from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $15–40
- Website
- Amtrak
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
- Website
- walpolealgonacferry.ca
Car ferry from Walpole Island, ON to Algonac, MI
- Ave. Duration
- 15 min
- Frequency
- On demand
- Estimated price
- $9
- Schedules at
- walpoleislandferry.ca
Car ferry from Walpole Island, ON to Algonac, MI
- Ave. Duration
- 15 min
- Frequency
- On demand
- Estimated price
- $9
- Schedules at
- walpoleislandferry.ca
Car ferry from Walpole Island, ON to Algonac, MI
- Ave. Duration
- 15 min
- Frequency
- On demand
- Estimated price
- $9
- Schedules at
- walpoleislandferry.ca
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