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How to get fromSarnia to Louisvilleby bus (Amtrak), train, bus, car, plane, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Sarnia to Louisville by bus (Amtrak), train, bus, car, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Chicago (Amtrak)

    best
    1. Take the bus from Port Huron Station to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    14h 25m
    $171–228

  2. Bus

    cheapest
    1. Take the bus from Sarnia to Londonbus bus
    2. Take the bus from London to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Cincinnati Bus Stationbus bus
    4. Take the bus from Greyhound Station Cincinnati to Louisville, KY Bus Stationbus bus
    14h 40m
    $64–161

  3. Train, bus (Amtrak)

    1. Take the train from Port Huron Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    15h 44m
    $186–383

  4. Drive 420.2 mi

    1. Drive from Sarnia to Louisvillecar car 420.2 mi
    7h 10m
    $97–139

  5. Train to Bishop International Airport, fly to Louisville International Airport

    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Fly from Bishop International Airport (FNT) to Louisville International Airport (SDF)plane plane FNT - SDF
    8h 58m
    $141–569

  6. Train, bus to Mbs International Airport, fly to Louisville International Airport

    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Take the bus from Flint Amtrak to Saginaw Bus Centerbus bus
    3. Fly from Mbs International Airport (MBS) to Louisville International Airport (SDF)plane plane MBS - SDF
    9h 41m
    $125–542

  7. Train, bus to Detroit, fly to Louisville International Airport

    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Take the bus from Flint Amtrak to Detroit Greyhoundbus bus
    3. Fly from Detroit (DTW) to Louisville International Airport (SDF)plane plane DTW - SDF
    9h 4m
    $117–625

  8. Train, bus to Detroit, fly to Blue Grass Airport, drive

    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Take the bus from Flint Amtrak to Detroit Greyhoundbus bus
    3. Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane plane DTW - LEX
    4. Drive from Lexington-Airport-LEX to Louisvillecar car
    9h 9m
    $169–891

Sarnia to Louisville by bus (Amtrak)

Calendar1Weekly Buses
Duration14h 25mAverage Duration
Ticket$171Cheapest Price
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Questions & Answers

Map of how to get from Sarnia to Louisville.ExpandLaunch map view
  • Distance: 643.3 mi
  • Duration: 14h 25m

What companies run services between Sarnia, ON, Canada and Louisville, KY, USA?

You can take a bus from Port Huron Station to Louisville, KY via Chicago Union Station in around 14h 25m.

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