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How to get fromSaskatoon to Mayo Clinicby plane, bus, car, or train

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There are 5 ways to get from Saskatoon to Mayo Clinic by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Saskatoon John G. Diefenbaker International Airport (YXE) to Rochester (RST)plane plane YXE - RST
    7h 40m
    $149–587

  2. Bus, drive, train via Regina

    1. Take the bus from Saskatoon to Reginabus bus
    2. Take the bus from Regina to Lethbridgebus bus
    3. Drive from Lethbridge to Port of Sweet Grasscar car
    4. Take the bus from Port of Sweet Grass to Shelby Transit Centerbus bus
    5. Take the train from Shelby Amtrak Station to St. Paul-Minneapolistrain train
    6. Take the bus from St. Paul to Rochester, MNbus bus
    38h 33m
    $490–936

  3. Drive 982.7 mi

    1. Drive from Saskatoon to Mayo Cliniccar car 982.7 mi
    17h 33m
    $225–325

  4. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Saskatoon John G. Diefenbaker International Airport (YXE) to Minneapolis–Saint Paul International Airport (MSP)plane plane YXE - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 13m
    $211–728

  5. Bus, drive, train

    1. Take the bus from Saskatoon to Calgarybus bus
    2. Take the bus from Calgary to Lethbridgebus bus
    3. Drive from Lethbridge to Port of Sweet Grasscar car
    4. Take the bus from Port of Sweet Grass to Shelby Transit Centerbus bus
    5. Take the train from Shelby Amtrak Station to St. Paul-Minneapolistrain train
    6. Take the bus from St. Paul to Rochester, MNbus bus
    41h 33m
    $522–965

Saskatoon John G. Diefenbaker International Airport (YXE) to Rochester (RST) flights

Calendar30Weekly Planes
Duration8h 6mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

Map of how to get from Saskatoon to Mayo Clinic.ExpandLaunch map view
  • Distance: 876.2 mi
  • Duration: 7h 40m

What companies run services between Saskatoon, SK, Canada and Mayo Clinic, MN, USA?

WestJet and Delta fly from Saskatoon John G. Diefenbaker International Airport (YXE) to Rochester (RST) 4 times a day.

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Train operators
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