There are 7 ways to get from Savannah to Mayo Clinic by plane, bus (Flixbus, Greyhound), train, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Savannah to Rochester
best- Fly from Savannah (SAV) to Rochester (RST)plane SAV - RST
6h 59m$144–640Bus
- Take the bus from Savannah Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to Rochesterbus
30h 36m$233–389Train, bus via Madison
- Take the train from Savannah Station to Chicago Union Stationtrain
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
41h 48m$851–1,321Drive 1,247.2 mi
- Drive from Savannah to Mayo Cliniccar 1,247.2 mi
21h 25m$214–308Fly Savannah to Minneapolis–Saint Paul International Airport, bus
- Fly from Savannah (SAV) to Minneapolis–Saint Paul International Airport (MSP)plane SAV - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
6h 29m$233–800Taxi to Hilton Head Airport, fly to Rochester
- Take the taxi from Savannah to Hilton Head Airport (HHH)taxi
- Fly from Hilton Head Airport (HHH) to Rochester (RST)plane HHH - RST
11h 26m$233–668Train, bus
- Take the train from Savannah Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochesterbus
43h 6m$1,024–1,581
Savannah to Mayo Clinic by bus and foot
Comparing Your Travel Options
The cheapest way to get from Savannah to Mayo Clinic is to drive which costs $210 - $310 and takes 21h 25m.
The fastest way to get from Savannah to Mayo Clinic is to fly and bus which takes 6h 29m and costs $230 - $800.
No, there is no direct bus from Savannah station to Mayo Clinic. However, there are services departing from Savannah Bus Station and arriving at Rochester via Atlanta Bus Station, Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 30h 36m.
The distance between Savannah and Mayo Clinic is 1042 miles. The road distance is 1254.4 miles.
The best way to get from Savannah to Mayo Clinic without a car is to bus which takes 30h 36m and costs $230 - $390.
It takes approximately 6h 59m to get from Savannah to Mayo Clinic, including transfers.
Savannah to Mayo Clinic bus services, operated by Flixbus USA, depart from Savannah Bus Station.
The best way to get from Savannah to Mayo Clinic is to fly which takes 6h 59m and costs $140 - $650. Alternatively, you can bus, which costs $230 - $390 and takes 30h 36m.
Savannah to Mayo Clinic bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Savannah to Mayo Clinic is 1254 miles. It takes approximately 21h 25m to drive from Savannah to Mayo Clinic.
What companies run services between Savannah, GA, USA and Mayo Clinic, MN, USA?
Delta, American Airlines, and United Airlines fly from Savannah (SAV) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Savannah Bus Station to Mayo Clinic via Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 30h 36m.
- Website
- delta.com
Flights from Savannah to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $110–550
Flights from Savannah to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- $140–700
Flights from Savannah to Minneapolis–Saint Paul International Airport via Atlanta
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $140–700
Flights from Hilton Head Airport to Rochester via Atlanta, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 11h 48m
- When
- Sunday
- Estimated price
- $100–490
Flights from Hilton Head Airport to Rochester via Philadelphia, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 10h 51m
- When
- Saturday
- Estimated price
- $120–600
- Website
- aa.com
Flights from Savannah to Rochester via Chicago O'Hare
- Ave. Duration
- 7h 16m
- When
- Every day
- Estimated price
- $100–550
Flights from Hilton Head Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 10h 29m
- When
- Every day
- Estimated price
- $90–460
Flights from Hilton Head Airport to Rochester via Reagan Washington, Chicago O'Hare
- Ave. Duration
- 9h 15m
- When
- Every day
- Estimated price
- $110–550
Flights from Hilton Head Airport to Rochester via Philadelphia, Chicago O'Hare
- Ave. Duration
- 12h 2m
- When
- Saturday
- Estimated price
- $120–550
- Website
- southwest.com
Flights from Savannah to Minneapolis–Saint Paul International Airport via Nashville
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $140–700
Flights from Savannah to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 5h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
Flights from Savannah to Minneapolis–Saint Paul International Airport via St. Louis
- Ave. Duration
- 6h 15m
- When
- Saturday
- Estimated price
- $140–700
- Website
- suncountry.com
Flights from Savannah to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 3m
- When
- Friday
- Estimated price
- $140–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Savannah Station to Chicago Union Station
- Ave. Duration
- 32h 4m
- Frequency
- Once daily
- Estimated price
- $750–1,200
- Website
- Amtrak
Train from Savannah Station to Chicago Union Station
- Ave. Duration
- 32h 4m
- Frequency
- Once daily
- Estimated price
- $750–1,200
- Website
- Amtrak
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $220–350
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Savannah Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h 10m
- Frequency
- 3 times a day
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Savannah Bus Station to Atlanta Bus Station
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h
- Frequency
- 4 times a day
- Estimated price
- $130–200
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $16–24
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Ave. Duration
- 49 min
- Estimated price
- $140–170
East Side Taxi
- Phone
- +19125722213
Elite Taxi
- Phone
- +1 706-513-3721
- Website
- taxisavannah.net
Yellow Cab of Savannah
- Phone
- +1 912-236-1133
- Website
- yellowcabsavannah.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 76+ hotels available in Mayo Clinic.















