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How to get fromSayre to Chicagoby bus, plane, taxi, train, bus (Greyhound), or car

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There are 9 ways to get from Sayre to Chicago by bus, plane, taxi, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, bus to Rochester, fly to Chicago Midway International Airport

    best
    1. Take the bus from Robert Packer Hospital to Transit Center - Railroad Avebus bus
    2. Take the bus from Elmira to Rochesterbus bus
    3. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane plane ROC - MDW
    8h 46m
    $144–712

  2. Bus, bus to Syracuse Hancock International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Robert Packer Hospital to Transit Center - Railroad Avebus bus
    2. Take the bus from Elmira to Binghamton, Nybus bus
    3. Take the bus from Binghamton to Syracusebus bus
    4. Fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD)plane plane SYR - ORD
    10h 21m
    $80–363

  3. Taxi, bus, train

    1. Take the taxi from Sayre to Ithacataxi taxi
    2. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    3. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    16h 15m
    $448–707

  4. Bus

    1. Take the bus from Robert Packer Hospital to Transit Center - Railroad Avebus bus 10
    2. Take the bus from Elmira to Buffalobus bus
    3. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    4. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    17h 55m
    $126–199

  5. Drive  664.3 mi

    1. Drive from Sayre to Chicagocar car 664.3 mi
    11h 21m
    $114–164

  6. Bus, bus to Rochester, fly to Chicago O'Hare International Airport

    1. Take the bus from Robert Packer Hospital to Transit Center - Railroad Avebus bus
    2. Take the bus from Elmira to Rochesterbus bus
    3. Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane plane ROC - ORD
    9h
    $114–512

  7. Bus, bus to Wilkes-Barre/Scranton International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Robert Packer Hospital to Transit Center - Railroad Avebus bus
    2. Take the bus from Elmira to Scranton Bus Stationbus bus
    3. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Chicago O'Hare International Airport (ORD)plane plane AVP - ORD
    8h 31m
    $111–389

  8. Bus, bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Robert Packer Hospital to Transit Center - Railroad Avebus bus
    2. Take the bus from Elmira to Buffalobus bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    9h 56m
    $218–392

  9. Bus, train

    1. Take the bus from Robert Packer Hospital to Transit Center - Railroad Avebus bus 10
    2. Take the bus from Elmira to Rochesterbus bus 948
    3. Take the train from Rochester to Chicago Union Stationtrain train
    17h 38m
    $348–584

Sayre to Chicago by bus

Calendar7Weekly Buses
Duration17h 55mAverage Duration
Ticket$126Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sayre to Chicago.ExpandLaunch map view
  • Distance: 691.8 mi
  • Duration: 8h 46m

What companies run services between Sayre, PA, USA and Chicago, IL, USA?

You can take a bus from Robert Packer Hospital to Chicago Bus Station via Elmira, Buffalo, and Cleveland Bus Station in around 17h 55m.

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