There are 7 ways to get from Scranton to Buffalo Depew Station by bus, train, car, plane, bus (Flixbus), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train via Syracuse
best- Take the bus from Scranton to Syracuse Bus Stationbus FlixBus N2686
- Take the train from Syracuse Regional Transportation Center to Buffalo Depew Stationtrain Empire Service / ...
5h 37m$55–209Drive 231.6 mi
cheapest- Drive from Scranton to Buffalo Depew Stationcar 231.6 mi
4h 58m$43–62Bus, train
- Take the bus from Scranton, Pa to Rochester, Nybus 246
- Take the train from Rochester to Buffalo Depew Stationtrain Lake Shore Limited / ...
6h 25m$49–268Fly from Wilkes-Barre/Scranton International Airport
- Fly from Wilkes-Barre/Scranton International Airport (AVP) to Buffalo Niagara International Airport (BUF)plane AVP - BUF
3h 42m$163–763Bus (Flixbus)
- Take the bus from Scranton to Buffalobus FlixBus 2685 / ...
7h 38m$47–69Bus via Scranton Bus Station (Greyhound)
- Take the bus from Scranton Bus Station to Buffalobus Greyhound US0205 / ...
8h 6m$46–70Bus to Newark Liberty International Airport, fly
- Take the bus from Scranton to Newark Penn Stationbus
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
5h 12m$116–543
Scranton to Buffalo Depew Station by bus and train
Comparing Your Travel Options
The cheapest way to get from Scranton to Buffalo Depew Station is to drive which costs $40 - $65 and takes 4h 58m.
The fastest way to get from Scranton to Buffalo Depew Station is to fly which takes 3h 42m and costs $160 - $800.
No, there is no direct bus from Scranton to Buffalo Depew Station. However, there are services departing from Scranton and arriving at Walden Avenue & 2929 Walden Avenue via Ellicott Street & MTC Static and Walden Avenue & Thruway Transit Center. The journey, including transfers, takes approximately 7h 38m.
The distance between Scranton and Buffalo Depew Station is 275 miles. The road distance is 233 miles.
The best way to get from Scranton to Buffalo Depew Station without a car is to bus and train via Syracuse which takes 5h 37m and costs $55 - $210.
It takes approximately 5h 37m to get from Scranton to Buffalo Depew Station, including transfers.
Scranton to Buffalo Depew Station bus services, operated by Flixbus USA, depart from Scranton station.
The best way to get from Scranton to Buffalo Depew Station is to fly which takes 3h 42m and costs $160 - $800. Alternatively, you can bus, which costs $45 - $70 and takes 7h 38m.
Scranton to Buffalo Depew Station bus services, operated by Flixbus USA, arrive at Buffalo station.
Yes, the driving distance between Scranton to Buffalo Depew Station is 233 miles. It takes approximately 4h 58m to drive from Scranton to Buffalo Depew Station.
What companies run services between Scranton, PA, USA and Buffalo Depew Station, NY, USA?
United Airlines and American Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Buffalo Niagara International Airport (BUF) 5 times a day. Alternatively, Flixbus USA operates a bus from Scranton to Buffalo twice daily. Tickets cost $40–65 and the journey takes 5h 25m.
- Website
- united.com
Flights from Wilkes-Barre/Scranton International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $110–700
Flights from Wilkes-Barre/Scranton International Airport to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- $190–950
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $70–480
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Buffalo Depew Station
- Ave. Duration
- 2h 22m
- Frequency
- 5 times a day
- Estimated price
- $30–85
- Website
- Amtrak
Train from Rochester to Buffalo Depew Station
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- $15–40
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Scranton to Syracuse Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $19–30
- Schedules at
- Flixbus USA
Bus from Scranton to Buffalo
- Ave. Duration
- 5h 25m
- Frequency
- Twice daily
- Estimated price
- $40–65
- Schedules at
- Flixbus USA
Bus from Scranton to Newark Penn Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $16–25
- Schedules at
- Flixbus USA
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Booking & Getting There
There are 257+ hotels available in Buffalo Depew Station.






