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How to get fromSeaTac to Knoxvilleby plane, train, bus, bus (Greyhound, Flixbus), or car

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There are 7 ways to get from SeaTac to Knoxville by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Seattle-Tacoma International Airport (SEA) to Mcghee Tyson Airport (TYS)plane plane SEA - TYS
    6h 54m
    $330–1,220

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Seattle-Tacoma International Airport (SEA) to Asheville Regional Airport (AVL)plane plane SEA - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    8h 49m
    $151–573

  3. Train, bus

    1. Take the train from Seattle to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 10h
    $871–2,016

  4. Bus

    1. Take the bus from Seattle Bus Station to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to New York Midtownbus bus
    4. Take the bus from New York to Knoxvillebus bus
    3d 14h
    $696–1,076

  5. Drive  2,545.2 mi

    1. Drive from SeaTac to Knoxvillecar car 2,545.2 mi
    41h 23m
    $465–671

  6. Fly to Nashville, drive

    1. Fly from Seattle-Tacoma International Airport (SEA) to Nashville (BNA)plane plane SEA - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    7h 12m
    $207–443

  7. Bus, train

    1. Take the bus from Seattle-Tacoma International Airport to Vancouver Waterfront Station, BCbus bus
    2. Take the train from Vancouver to Toronto Union Stationtrain train
    3. Take the train from Toronto Union Station to New York Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus
    5d 6h
    $1,069–2,137

Seattle-Tacoma International Airport (SEA) to Mcghee Tyson Airport (TYS) flights

Calendar111Weekly Planes
Duration7h 45mAverage Duration
Ticket$274Cheapest Price
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Comparing Your Travel Options

Map of how to get from SeaTac to Knoxville.ExpandLaunch map view
  • Distance: 2,122.4 mi
  • Duration: 6h 54m

What companies run services between SeaTac, WA, USA and Knoxville, TN, USA?

Delta, Southwest Airlines, and three other airlines fly from Seattle-Tacoma International Airport (SEA) to Mcghee Tyson Airport (TYS) hourly. Alternatively, you can take a bus from SeaTac Station to Knoxville via Bus Wy & Royal Brougham St, Seattle Bus Station, Denver Union Station, Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 3d 14h.

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