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How to get fromSeattle Airport (SEA) to Mayo Clinicby plane, bus (Flixbus), train, bus, or car

Find Transport to Mayo Clinic

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There are 5 ways to get from Seattle Airport (SEA) to Mayo Clinic by plane, bus (Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Seattle-Tacoma International Airport (SEA) to Rochester (RST)plane plane SEA - RST
    6h 20m
    $109–495

  2. Bus

    1. Take the bus from Seattle Tacoma Intl Airport to Spokane Stationbus bus
    2. Take the bus from Spokane to Billingsbus bus
    3. Take the bus from Billings to Minneapolisbus bus
    4. Take the bus from Minneapolis to Rochesterbus bus
    36h 8m
    $377–562

  3. Train, bus

    1. Take the train from Seattle to St. Paul-Minneapolistrain train Empire Builder
    2. Take the bus from St. Paul to Rochesterbus bus Jefferson Lines 965
    41h 52m
    $584–1,246

  4. Drive 1,708.8 mi

    1. Drive from Seattle Airport (SEA) to Mayo Cliniccar car 1,708.8 mi
    26h 38m
    $312–451

  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Seattle-Tacoma International Airport (SEA) to Minneapolis–Saint Paul International Airport (MSP)plane plane SEA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 9m
    $236–2,280

Seattle Airport (SEA) to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration36h 8mAverage Duration
Ticket$377Cheapest Price
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Questions & Answers

Map of how to get from Seattle Airport (SEA) to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,459.8 mi
  • Duration: 6h 20m

What companies run services between Seattle Airport (SEA), USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from Seattle-Tacoma International Airport (SEA) to Rochester (RST) every 3 hours. Alternatively, you can take a bus from Seattle Tacoma Intl Airport to Mayo Clinic via Spokane Station, Spokane, Billings, Minneapolis, and Rochester in around 36h 8m.

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