Rome2Rio

How to get fromSeattle to Mayo Clinicby plane, train, bus, or car

Find Transport to Mayo Clinic

See all options

There are 4 ways to get from Seattle to Mayo Clinic by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Seattle-Tacoma International Airport (SEA) to Rochester (RST)plane plane SEA - RST
    8h 18m
    $117–516
  2. Train, bus

    1. Take the train from Seattle to St. Paul-Minneapolistrain train Empire Builder
    2. Take the bus from St. Paul to Rochester, MNbus bus Minneapolis / ...
    40h 16m
    $616–1,217
  3. Drive 1,705.9 mi

    1. Drive from Seattle to Mayo Cliniccar car 1,705.9 mi
    26h 27m
    $312–450
  4. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Seattle-Tacoma International Airport (SEA) to Minneapolis–Saint Paul International Airport (MSP)plane plane SEA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 6m
    $248–2,458

Seattle to Mayo Clinic by train, bus, and foot

Calendar7Weekly Services
Duration40h 16mAverage Duration
Ticket$616Cheapest Price
See schedules

Questions & Answers

What companies run services between Seattle, WA, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from Seattle-Tacoma International Airport (SEA) to Rochester (RST) every 3 hours.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides