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How to get fromSeattle to Mayo Clinicby plane, bus (Flixbus), train, bus, or car

Find Transport to Mayo Clinic

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There are 5 ways to get from Seattle to Mayo Clinic by plane, bus (Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Seattle-Tacoma International Airport (SEA) to Rochester (RST)plane plane SEA - RST
    8h 16m
    $99–483

  2. Bus

    1. Take the bus from Seattle Greyhound to Spokanebus bus
    2. Take the bus from Spokane to Billingsbus bus
    3. Take the bus from Billings to Minneapolisbus bus
    4. Take the bus from Minneapolis to Rochesterbus bus
    37h 23m
    $389–617

  3. Train, bus

    1. Take the train from Seattle to St. Paul-Minneapolistrain train Empire Builder
    2. Take the bus from St. Paul to Rochesterbus bus Jefferson Lines 965
    40h 11m
    $497–1,066

  4. Drive  1,705.9 mi

    1. Drive from Seattle to Mayo Cliniccar car 1,705.9 mi
    26h 27m
    $312–450

  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Seattle-Tacoma International Airport (SEA) to Minneapolis–Saint Paul International Airport (MSP)plane plane SEA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 49m
    $235–2,355

Seattle to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration37h 23mAverage Duration
Ticket$389Cheapest Price
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Comparing Your Travel Options

Map of how to get from Seattle to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,474.1 mi
  • Duration: 8h 16m

What companies run services between Seattle, WA, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from Seattle-Tacoma International Airport (SEA) to Rochester (RST) every 3 hours. Alternatively, you can take a bus from Seattle Greyhound to Mayo Clinic via Spokane, Billings, Minneapolis, and Rochester in around 37h 23m.

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