There are 5 ways to get from Sedalia to Cape Girardeau by train, bus, bus (Greyhound), car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Sedalia Amtrak Station to St. Louistrain Missouri River Runner / ...
- Take the bus from St Louis Bus Station to Cape Girardeaubus Greyhound US1173
7h$84–166Drive 262.7 mi
cheapest- Drive from Sedalia to Cape Girardeaucar 262.7 mi
5h 18m$48–70Bus
- Take the bus from La Monte to St Louis Bus Stationbus Greyhound US0175s
- Take the bus from St Louis Bus Station to Cape Girardeaubus Greyhound US1173
8h 26m$100–167Drive, fly to Williamson County Regional Airport, taxi
- Drive from Sedalia to Columbia Regional Airport (COU)car
- Fly from Columbia Regional Airport (COU) to Williamson County Regional Airport (MWA)plane COU - MWA
- Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi
6h 31m$215–561Drive, fly to Barkley Regional Airport, taxi
- Drive from Sedalia to Columbia Regional Airport (COU)car
- Fly from Columbia Regional Airport (COU) to Barkley Regional Airport (PAH)plane COU - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi
9h 47m$225–561
Columbia Regional Airport (COU) to Williamson County Regional Airport (MWA) flights
Questions & Answers
The cheapest way to get from Sedalia to Cape Girardeau is to drive which costs $45 - $70 and takes 5h 18m.
The fastest way to get from Sedalia to Cape Girardeau is to drive which takes 5h 18m and costs $45 - $70.
No, there is no direct bus from Sedalia to Cape Girardeau. However, there are services departing from La Monte and arriving at Cape Girardeau via St Louis Bus Station. The journey, including transfers, takes approximately 8h 26m.
The distance between Sedalia and Cape Girardeau is 302 miles. The road distance is 264.2 miles.
The best way to get from Sedalia to Cape Girardeau without a car is to train and bus which takes 7h and costs $80 - $170.
It takes approximately 7h to get from Sedalia to Cape Girardeau, including transfers.
Sedalia to Cape Girardeau bus services, operated by Greyhound-us, depart from La Monte station.
Sedalia to Cape Girardeau bus services, operated by Greyhound-us, arrive at St Louis Bus Station.
Yes, the driving distance between Sedalia to Cape Girardeau is 264 miles. It takes approximately 5h 18m to drive from Sedalia to Cape Girardeau.
Book your Sedalia to Cape Girardeau bus tickets online with Omio.
What companies run services between Sedalia, MO, USA and Cape Girardeau, MO, USA?
You can take a vehicle from Sedalia to Cape Girardeau via La Monte, St Louis Bus Station, and Cape Girardeau in around 8h 26m.
- Website
- contouraviation.com
Flights from Columbia Regional Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $70–380
- Website
- united.com
Flights from Columbia Regional Airport to Barkley Regional Airport via Chicago O'Hare
- Ave. Duration
- 7h 2m
- When
- Every day
- Estimated price
- $70–370
- Website
- aa.com
Flights from Columbia Regional Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $70–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Sedalia Amtrak Station to St. Louis
- Ave. Duration
- 3h 51m
- Frequency
- Twice daily
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
- Website
- greyhound.com
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from La Monte to St Louis Bus Station
- Ave. Duration
- 5h 5m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
Bus from La Monte to St Louis Bus Station
- Ave. Duration
- 5h 5m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
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More Questions & Answers
There are 24+ hotels available in Cape Girardeau.






