There are 8 ways to get from Sedalia to Indianapolis by train, bus, car, plane, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus via St. Louis
best- Take the train from Sedalia Amtrak Station to St. Louistrain Missouri River Runner / ...
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus Greyhound US0421
9h 16m$96–190Drive 423.3 mi
cheapest- Drive from Sedalia to Indianapoliscar 423.3 mi
7h 10m$78–112Train, bus
- Take the train from Sedalia Amtrak Station to Bloomington-Normaltrain Lincoln Service Missouri River Runner
- Take the bus from Bloomington-Normal to Indianapolis Union Stationbus Greyhound US0157S
11h 20m$139–273Drive to Columbia Regional Airport, fly to Indianapolis
- Drive from Sedalia to Columbia Regional Airport (COU)car
- Fly from Columbia Regional Airport (COU) to Indianapolis (IND)plane COU - IND
6h 16m$102–513Train, bus via Warrensburg
- Take the train from Sedalia Amtrak Station to Warrensburg Amtrak Stationtrain
- Take the bus from Warrensburg Chamber Of Commerce to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
12h 41m$85–169Train (Amtrak)
- Take the train from Sedalia Amtrak Station to Chicago Union Stationtrain Lincoln Service Missouri River Runner
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
15h 27m$214–433Train to Kansas City, fly to Indianapolis
- Take the train from Sedalia Amtrak Station to Kansas Citytrain
- Fly from Kansas City (MCI) to Indianapolis (IND)plane MCI - IND
7h 33m$683–1,063Drive to Columbia Regional Airport, fly to Purdue University Airport, train
- Drive from Sedalia to Columbia Regional Airport (COU)car
- Fly from Columbia Regional Airport (COU) to Purdue University Airport (LAF)plane COU - LAF
- Take the train from Lafayette Amtrak Station to Indianapolistrain
10h 16m$95–402
Sedalia to Indianapolis by train and bus
Questions & Answers
The cheapest way to get from Sedalia to Indianapolis is to drive which costs $75 - $120 and takes 7h 10m.
The fastest way to get from Sedalia to Indianapolis is to drive and fly which takes 6h 16m and costs $100 - $550.
No, there is no direct train from Sedalia station to Indianapolis. However, there are services departing from Sedalia Amtrak Station and arriving at Indianapolis via Chicago Union Station. The journey, including transfers, takes approximately 15h 27m.
The distance between Sedalia and Indianapolis is 430 miles. The road distance is 425.8 miles.
The best way to get from Sedalia to Indianapolis without a car is to train and bus via St. Louis which takes 9h 16m and costs $95 - $190.
It takes approximately 9h 16m to get from Sedalia to Indianapolis, including transfers.
Sedalia to Indianapolis train services, operated by Amtrak, depart from Sedalia Amtrak Station.
Indianapolis is 1h ahead of Sedalia. It is currently 6:17 PM in Sedalia and 7:17 PM in Indianapolis.
Sedalia to Indianapolis train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Sedalia to Indianapolis is 426 miles. It takes approximately 7h 10m to drive from Sedalia to Indianapolis.
What companies run services between Sedalia, MO, USA and Indianapolis, IN, USA?
You can take a train from Sedalia Amtrak Station to Indianapolis via Chicago Union Station in around 15h 27m.
- Website
- united.com
Flights from Columbia Regional Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $85–490
Flights from Columbia Regional Airport to Purdue University Airport via Chicago O'Hare
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $55–330
- Website
- aa.com
Flights from Columbia Regional Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $85–490
Flights from Columbia Regional Airport to Indianapolis via Dallas/Ft.Worth
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $160–750
Flights from Columbia Regional Airport to Indianapolis via Charlotte
- Ave. Duration
- 6h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
- Website
- southwest.com
Flights from Kansas City to Indianapolis
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $110–700
Flights from Kansas City to Indianapolis via Chicago Midway
- Ave. Duration
- 3h 30m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $130–750
Flights from Kansas City to Indianapolis via Nashville
- Ave. Duration
- 3h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $150–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Sedalia Amtrak Station to St. Louis
- Ave. Duration
- 3h 51m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- https://www.amtrak.com/home.html
Train from Sedalia Amtrak Station to Bloomington-Normal
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $110–230
- Website
- https://www.amtrak.com/home.html
Train from Sedalia Amtrak Station to Warrensburg Amtrak Station
- Ave. Duration
- 31 min
- Frequency
- Twice daily
- Estimated price
- $9–20
- Website
- https://www.amtrak.com/home.html
Train from Sedalia Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 33m
- Frequency
- Once daily
- Estimated price
- $150–310
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
Train from Sedalia Amtrak Station to Kansas City
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Train from Lafayette Amtrak Station to Indianapolis
- Ave. Duration
- 1h 53m
- Frequency
- 3 times a week
- Estimated price
- $24–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
Bus from Bloomington-Normal to Indianapolis Union Station
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
Bus from Warrensburg Chamber Of Commerce to St Louis Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Book your Sedalia to Indianapolis train tickets online with Omio.
There are 827+ hotels available in Indianapolis.






