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How to get fromSedalia to Knoxvilleby car, plane, train, bus, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Sedalia to Knoxville by car, plane, train, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Columbia Regional Airport, fly

    best
    1. Drive from Sedalia to Columbia Regional Airport (COU)car car
    2. Fly from Columbia Regional Airport (COU) to Mcghee Tyson Airport (TYS)plane plane COU - TYS
    6h 2m
    $250–1,091

  2. Drive  638.9 mi

    cheapest
    1. Drive from Sedalia to Knoxvillecar car 638.9 mi
    12h
    $117–169

  3. Train, bus via Farragut

    1. Take the train from Sedalia Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    44h 18m
    $940–1,498

  4. Train, bus

    1. Take the train from Sedalia Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d
    $506–740

  5. Train to Kansas City, fly

    1. Take the train from Sedalia Amtrak Station to Kansas Citytrain train
    2. Fly from Kansas City (MCI) to Mcghee Tyson Airport (TYS)plane plane MCI - TYS
    8h 44m
    $337–1,449

  6. Train to Lambert–St. Louis International Airport, fly

    1. Take the train from Sedalia Amtrak Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    9h 13m
    $310–1,180

  7. Train, bus via Ossining

    1. Take the train from Sedalia Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    44h 56m
    $905–1,375

  8. Bus

    1. Take the bus from La Monte to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d
    $359–503

Columbia Regional Airport (COU) to Mcghee Tyson Airport (TYS) flights

Calendar59Weekly Planes
Duration5h 35mAverage Duration
Ticket$188Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sedalia to Knoxville.ExpandLaunch map view
  • Distance: 591.1 mi
  • Duration: 6h 2m

What companies run services between Sedalia, MO, USA and Knoxville, TN, USA?

You can take a vehicle from Sedalia to Knoxville Station Hall of Fame via La Monte, St Louis Bus Station, Newark Penn Station, New York, NY, Knoxville, TN, Walmart, and Fountain City Superstop in around 2d.

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