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How to get fromSedalia to Knoxvilleby car, plane, train, bus, or bus (Greyhound)

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There are 8 ways to get from Sedalia to Knoxville by car, plane, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Columbia Regional Airport, fly

    best
    1. Drive from Sedalia to Columbia Regional Airport (COU)car car
    2. Fly from Columbia Regional Airport (COU) to Mcghee Tyson Airport (TYS)plane plane COU - TYS
    6h 18m
    $220–841

  2. Drive 638.9 mi

    cheapest
    1. Drive from Sedalia to Knoxvillecar car 638.9 mi
    12h
    $117–169

  3. Train, bus

    1. Take the train from Sedalia Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    44h 18m
    $645–1,207

  4. Bus

    1. Take the bus from La Monte to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    44h 35m
    $419–696

  5. Train to Kansas City, fly

    1. Take the train from Sedalia Amtrak Station to Kansas Citytrain train
    2. Fly from Kansas City (MCI) to Mcghee Tyson Airport (TYS)plane plane MCI - TYS
    8h 44m
    $266–1,081

  6. Train to Lambert–St. Louis International Airport, fly

    1. Take the train from Sedalia Amtrak Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    9h 50m
    $248–994

  7. Train, bus via Ossining

    1. Take the train from Sedalia Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    44h 55m
    $600–1,134

  8. Train, bus #2

    1. Take the train from Sedalia Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d
    $411–689

Columbia Regional Airport (COU) to Mcghee Tyson Airport (TYS) flights

Calendar62Weekly Planes
Duration5h 39mAverage Duration
Ticket$149Cheapest Price
See schedules

Questions & Answers

Map of how to get from Sedalia to Knoxville.ExpandLaunch map view
  • Distance: 591.1 mi
  • Duration: 6h 18m

What companies run services between Sedalia, MO, USA and Knoxville, TN, USA?

You can take a vehicle from Sedalia to Knoxville via La Monte, St Louis Bus Station, Port Authority Bus Terminal, 42 St-Bryant Park, East Broadway, New York, and Knoxville in around 44h 35m.

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