Rome2Rio

How to get fromSedalia to Lexingtonby car, plane, train, or bus

Find Transport to Lexington

See all options

There are 5 ways to get from Sedalia to Lexington by car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, fly to Louisville International Airport

    best
    1. Drive from Sedalia to Columbia Regional Airport (COU)car car
    2. Fly from Columbia Regional Airport (COU) to Louisville International Airport (SDF)plane plane COU - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 28m
    $149–742

  2. Drive, fly to Blue Grass Airport

    cheapest
    1. Drive from Sedalia to Columbia Regional Airport (COU)car car
    2. Fly from Columbia Regional Airport (COU) to Blue Grass Airport (LEX)plane plane COU - LEX
    8h 1m
    $82–413

  3. Train, bus, drive

    1. Take the train from Sedalia Amtrak Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Corydon, INbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    14h 35m
    $234–402

  4. Drive  526.3 mi

    1. Drive from Sedalia to Lexingtoncar car 526.3 mi
    8h 59m
    $96–139

  5. Bus, drive

    1. Take the bus from La Monte to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    17h 57m
    $158–309

Columbia Regional Airport (COU) to Louisville International Airport (SDF) flights

Calendar44Weekly Planes
Duration5h 10mAverage Duration
Ticket$121Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Sedalia to Lexington.ExpandLaunch map view
  • Distance: 513.2 mi
  • Duration: 7h 28m

What companies run services between Sedalia, MO, USA and Lexington, KY, USA?

There is no direct connection from Sedalia to Lexington. However, you can drive to Columbia Regional Airport (COU) airport, fly to Louisville International Airport (SDF), then drive to Lexington. Alternatively, you can take a train from Sedalia Amtrak Station to Lexington via St. Louis, St Louis Bus Station, Evansville, IN, Corydon, IN, S 5th @ W Jefferson, and Middletown Station @ Target in around 14h 35m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound