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How to get fromSedalia to Sioux Fallsby car, plane, train, or bus

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There are 5 ways to get from Sedalia to Sioux Falls by car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Columbia Regional Airport, fly

    best
    1. Drive from Sedalia to Columbia Regional Airport (COU)car car
    2. Fly from Columbia Regional Airport (COU) to Sioux Falls (FSD)plane plane COU - FSD
    7h 14m
    $92–433

  2. Drive  445 mi

    cheapest
    1. Drive from Sedalia to Sioux Fallscar car 445 mi
    7h 24m
    $82–118

  3. Train, bus

    1. Take the train from Sedalia Amtrak Station to Kansas Citytrain train Missouri River Runner / ...
    2. Take the bus from Kansas City to Sioux Fallsbus bus Jefferson Lines 705
    12h 35m
    $160–236

  4. Train to Kansas City, fly

    1. Take the train from Sedalia Amtrak Station to Kansas Citytrain train
    2. Fly from Kansas City (MCI) to Sioux Falls (FSD)plane plane MCI - FSD
    9h 50m
    $144–631

  5. Train to Lambert–St. Louis International Airport, fly

    1. Take the train from Sedalia Amtrak Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Sioux Falls (FSD)plane plane STL - FSD
    10h 31m
    $187–601

Columbia Regional Airport (COU) to Sioux Falls (FSD) flights

Calendar62Weekly Planes
Duration6h 12mAverage Duration
Ticket$78Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sedalia to Sioux Falls.ExpandLaunch map view
  • Distance: 490.5 mi
  • Duration: 7h 14m

What companies run services between Sedalia, MO, USA and Sioux Falls, SD, USA?

There is no direct connection from Sedalia to Sioux Falls. However, you can drive to Columbia Regional Airport (COU) airport, fly to Sioux Falls (FSD), walk to 4th Ave/Wells Fargo crosswalk, then take the line 8 bus to Cliff/3rd NW corner. Alternatively, you can take a train from Sedalia Amtrak Station to Sioux Falls via Kansas City, On Grand At Pershing Farside Northbound, On 12Th At Charlotte Eastbound Nearside, Kansas City, and Sioux Falls in around 12h 35m.

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