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How to get fromSeffner to Panama City Beachby bus (Flixbus, Greyhound), car, plane, bus (Greyhound), or bus

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There are 7 ways to get from Seffner to Panama City Beach by bus (Flixbus, Greyhound), car, plane, bus (Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Gainesville

    best
    1. Take the bus from University of South Florida to Gainesvillebus bus
    2. Take the bus from Gainesville to Tallahasseebus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    9h 17m
    $107–169

  2. Drive 343.1 mi

    cheapest
    1. Drive from Seffner to Panama City Beachcar car 343.1 mi
    6h 49m
    $63–91

  3. Fly to Northwest Florida Beaches International Airport

    1. Fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP)plane plane TPA - ECP
    6h 42m
    $131–461

  4. Bus

    1. Take the bus from Tampa Bus Station to Tallahasseebus bus Greyhound US0780s
    2. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus Greyhound US0799 / ...
    10h 46m
    $64–126

  5. Bus #2

    1. Take the bus from Tampa USF to Tallahassee FSUbus bus Miami–Tallahassee via Tampa
    2. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus Greyhound US0799 / ...
    12h 7m
    $96–183

  6. Fly to Destin–Fort Walton Beach Airport, drive

    1. Fly from Tampa (TPA) to Destin–Fort Walton Beach Airport (VPS)plane plane TPA - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    7h 42m
    $91–412

  7. Fly to Pensacola International Airport, bus

    1. Fly from Tampa (TPA) to Pensacola International Airport (PNS)plane plane TPA - PNS
    2. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    7h 43m
    $190–548

Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) flights

Calendar86Weekly Planes
Duration5h 30mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Seffner to Panama City Beach.ExpandLaunch map view
  • Distance: 389.9 mi
  • Duration: 9h 17m

What companies run services between Seffner, FL, USA and Panama City Beach, FL, USA?

You can take a vehicle from Seffner to Panama City Beach via University of South Florida, Gainesville, Tallahassee, and Panama City Beach Bus Station in around 9h 17m. Alternatively, Delta, Southwest Airlines, and two other airlines fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) every 2 hours.

Airlines
Bus operators

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