There are 6 ways to get from Seffner to Panama City Beach by bus (Greyhound), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Tampa Bus Station to Tallahasseebus Greyhound US0780s
- Take the bus from Tallahassee to Panama City Beach Bus Stationbus Greyhound US0799 / ...
8h 52m$103–153Drive 343.1 mi
cheapest- Drive from Seffner to Panama City Beachcar 343.1 mi
6h 49m$61–88Fly Tampa to Northwest Florida Beaches International Airport
- Fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP)plane TPA - ECP
6h 55m$121–441Fly Tampa to Pensacola International Airport, drive
- Fly from Tampa (TPA) to Pensacola International Airport (PNS)plane TPA - PNS
- Drive from Pensacola-Airport-PNS to Panama City Beachcar
6h 39m$78–351Fly Tampa to Destin–Fort Walton Beach Airport, drive
- Fly from Tampa (TPA) to Destin–Fort Walton Beach Airport (VPS)plane TPA - VPS
- Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar
7h 47m$81–392Bus to Sarasota–Bradenton International Airport, fly to Northwest Florida Beaches International Airport
- Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus
- Fly from Sarasota–Bradenton International Airport (SRQ) to Northwest Florida Beaches International Airport (ECP)plane SRQ - ECP
10h$134–476
Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) flights
Comparing Your Travel Options
The cheapest way to get from Seffner to Panama City Beach is to drive which costs $60 - $90 and takes 6h 49m.
The fastest way to get from Seffner to Panama City Beach is to fly and drive which takes 6h 39m and costs $75 - $360.
No, there is no direct bus from Seffner station to Panama City Beach station. However, there are services departing from Tampa Bus Station and arriving at Panama City Beach Bus Station via Tallahassee. The journey, including transfers, takes approximately 8h 52m.
The distance between Seffner and Panama City Beach is 359 miles. The road distance is 345.1 miles.
The best way to get from Seffner to Panama City Beach without a car is to bus which takes 8h 52m and costs $100 - $160.
It takes approximately 8h 52m to get from Seffner to Panama City Beach, including transfers.
Seffner to Panama City Beach bus services, operated by Greyhound USA, depart from Tampa Bus Station.
The best way to get from Seffner to Panama City Beach is to bus which takes 8h 52m and costs $100 - $160. Alternatively, you can fly, which costs $120 - $450 and takes 6h 55m.
Seffner to Panama City Beach bus services, operated by Greyhound USA, arrive at Tallahassee station.
Panama City Beach is 1h behind Seffner. It is currently 5:22 PM in Seffner and 4:22 PM in Panama City Beach.
What companies run services between Seffner, FL, USA and Panama City Beach, FL, USA?
You can take a vehicle from Seffner to Panama City Beach via Tampa Bus Station, Tallahassee, and Panama City Beach Bus Station in around 8h 52m. Alternatively, Delta, Southwest Airlines, and two other airlines fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) hourly.
- Website
- delta.com
Flights from Tampa to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $65–370
Flights from Tampa to Pensacola International Airport via Atlanta
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $55–320
Flights from Tampa to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $65–370
Flights from Sarasota–Bradenton International Airport to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $70–390
- Website
- southwest.com
Flights from Tampa to Northwest Florida Beaches International Airport via Nashville
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $85–430
Flights from Tampa to Northwest Florida Beaches International Airport via Houston Hobby Apt
- Ave. Duration
- 5h 5m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–480
Flights from Tampa to Northwest Florida Beaches International Airport via Indianapolis
- Ave. Duration
- 6h 50m
- When
- Saturday
- Estimated price
- $110–500
Flights from Tampa to Destin–Fort Walton Beach Airport via Nashville
- Ave. Duration
- 5h 45m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–430
Flights from Tampa to Destin–Fort Walton Beach Airport via Houston Hobby Apt
- Ave. Duration
- 5h 20m
- When
- Saturday
- Estimated price
- $100–480
Flights from Sarasota–Bradenton International Airport to Northwest Florida Beaches International Airport via Houston Hobby Apt
- Ave. Duration
- 5h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Sarasota–Bradenton International Airport to Northwest Florida Beaches International Airport via St. Louis
- Ave. Duration
- 6h 25m
- When
- Saturday
- Estimated price
- $120–550
Flights from Sarasota–Bradenton International Airport to Northwest Florida Beaches International Airport via Nashville
- Ave. Duration
- 7h 57m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $90–460
- Website
- aa.com
Flights from Tampa to Northwest Florida Beaches International Airport via Charlotte
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $80–420
Flights from Tampa to Destin–Fort Walton Beach Airport via Miami
- Ave. Duration
- 4h 7m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $70–380
Flights from Tampa to Destin–Fort Walton Beach Airport via Charlotte
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $80–420
Flights from Sarasota–Bradenton International Airport to Northwest Florida Beaches International Airport via Charlotte
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $90–450
- Website
- united.com
Flights from Tampa to Northwest Florida Beaches International Airport via Houston
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $100–480
- Website
- flybreeze.com
Flights from Tampa to Pensacola International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $110–700
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tampa Bus Station to Tallahassee
- Ave. Duration
- 5h 20m
- Frequency
- 4 times a day
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Tallahassee to Panama City Beach Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- $19–29
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Tampa Bus Station to Sarasota Cattlemen Transfer Center
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Seffner to Panama City Beach is 345 miles. It takes approximately 6h 49m to drive from Seffner to Panama City Beach.
Book your Seffner to Panama City Beach bus tickets online with Omio.
There are 5378+ hotels available in Panama City Beach.



