There are 8 ways to get from Seminole to Key West by bus, plane, ferry, train, car, shuttle, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 58 bus to Saint Petersburg–Clearwater International Airport, fly
best- Take the bus from Seminole Mall to Psta 34Th St Layby - Platform - Bbus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
3h 12m$51–258Amtrak Thruway, bus, ferry
- Take the bus from St. Petersburg to Sarasota Amtrak Bus Stopbus
- Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
11h 48m$205–236Train, bus
- Take the train from Tampa to Delray Beach Amtraktrain
- Take the train from Delray Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
13h 36m$158–272Drive 394 mi
- Drive from Seminole to Key Westcar 394 mi
7h 50m$72–104Line 300 bus to Tampa, fly
- Take the bus from Psta 34Th St Layby - Platform - D to TPA RENTAL CAR FACILITY westboundbus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
4h 35m$86–408Drive to Orlando Sanford, fly
- Drive from Seminole to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
3h 54m$69–297Amtrak Thruway, bus, shuttle
- Take the bus from St. Petersburg to Sarasota Amtrak Bus Stopbus
- Take the bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airportbus
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
14h 31m$245–340Bus
- Take the bus from Tampa Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
16h 50m$66–134
Seminole to Key West by bus, foot, and shuttle
Questions & Answers
The cheapest way to get from Seminole to Key West is to bus which costs $65 - $140 and takes 16h 50m.
The fastest way to get from Seminole to Key West is to line 58 bus and fly which takes 3h 12m and costs $50 - $260.
No, there is no direct bus from Seminole to Key West. However, there are services departing from Park Blvd + 110Th St and arriving at N Roosevelt & 3rd Street via Gateway Mall - Shelter - 4, Tampa Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 16h 50m.
The distance between Seminole and Key West is 256 miles. The road distance is 396.3 miles.
The best way to get from Seminole to Key West without a car is to Amtrak Thruway and bus and ferry which takes 11h 48m and costs $200 - $240.
It takes approximately 3h 12m to get from Seminole to Key West, including transfers.
Seminole to Key West bus services, operated by Flixbus USA, depart from Tampa Bus Station.
Seminole to Key West bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Seminole to Key West is 396 miles. It takes approximately 7h 50m to drive from Seminole to Key West.
There are 936+ hotels available in Key West.
What companies run services between Seminole, Pinellas County, FL, USA and Key West, FL, USA?
You can take a bus from Park Blvd + 110Th St to N Roosevelt & 3rd Street via Gateway Mall - Shelter - 4, Marion Transit Parking Lot, Tampa Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 16h 50m.
- Website
- allegiantair.com
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 4m
- When
- Monday, Friday, Wednesday, Saturday, Thursday, and Sunday
- Estimated price
- $35–240
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 20m
- When
- Sunday and Thursday
- Estimated price
- $35–250
- Website
- flybreeze.com
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 18m
- When
- Thursday, Sunday, Monday, Wednesday, Friday, and Tuesday
- Estimated price
- $70–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Tampa to Delray Beach Amtrak
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $65–140
- Website
- Amtrak
- Phone
- +1 800-874-7245
- [email protected]
- Website
- Tri Rail
Train from Delray Beach Station to Miami Airport Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $5–9
- Website
- Tri Rail
- Weekend | Holiday
- $5
- Weekday
- $6–9
- Phone
- +1 727-540-1900
- [email protected]
- Website
- Pinellas Suncoast Transit Authority
Bus from Seminole Mall to Psta 34Th St Layby - Platform - B
- Ave. Duration
- 27 min
- Frequency
- Hourly
- Estimated price
- $3
- Schedules at
- Pinellas Suncoast Transit Authority
- Adult
- $3
Bus from Psta 34Th St Layby - Platform - D to TPA RENTAL CAR FACILITY westbound
- Ave. Duration
- 32 min
- Frequency
- Every 3 hours
- Estimated price
- $3
- Schedules at
- Pinellas Suncoast Transit Authority
- Adult
- $3
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St. Petersburg to Sarasota Amtrak Bus Stop
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $16–24
- Website
- Amtrak
Bus from St. Petersburg to Sarasota Amtrak Bus Stop
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $16–24
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 6h 20m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- $19–40
- Website
- Greyhound
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 8h
- Frequency
- Twice daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- $19–40
- Website
- Greyhound
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airport
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- RedCoach
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide




















