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How to get fromSeneca to St. Louisby bus (Greyhound), car, plane, shuttle, or bus

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There are 6 ways to get from Seneca to St. Louis by bus (Greyhound), car, plane, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Joplin Bus Station to St Louis Bus Stationbus bus Greyhound US1210
    5h 58m
    $69–119

  2. Drive 299.7 mi

    cheapest
    1. Drive from Seneca to St. Louiscar car 299.7 mi
    5h 1m
    $55–79

  3. Drive to Northwest Arkansas Regional Airport, fly

    1. Drive from Seneca to Northwest Arkansas Regional Airport (XNA)car car
    2. Fly from Northwest Arkansas Regional Airport (XNA) to Lambert–St. Louis International Airport (STL)plane plane XNA - STL
    5h 53m
    $153–768

  4. Fly from Joplin Regional Airport

    1. Fly from Joplin Regional Airport (JLN) to Lambert–St. Louis International Airport (STL)plane plane JLN - STL
    7h 19m
    $143–638

  5. Shuttle to Springfield-Branson National Airport, fly

    1. Take a shuttle bus from Neosho Casey's to Springfieldshuttle bus
    2. Fly from Springfield-Branson National Airport (SGF) to Lambert–St. Louis International Airport (STL)plane plane SGF - STL
    7h 53m
    $142–602

  6. Bus to Kansas City, fly

    1. Take the bus from Joplin to Kansas Citybus bus
    2. Fly from Kansas City (MCI) to Lambert–St. Louis International Airport (STL)plane plane MCI - STL
    7h 23m
    $152–697

Northwest Arkansas Regional Airport (XNA) to Lambert–St. Louis International Airport (STL) flights

Calendar121Weekly Planes
Duration5h 18mAverage Duration
Ticket$146Cheapest Price
See schedules

Questions & Answers

Map of how to get from Seneca to St. Louis.ExpandLaunch map view
  • Distance: 317.8 mi
  • Duration: 5h 58m

What companies run services between Seneca, MO, USA and St. Louis, MO, USA?

Greyhound USA operates a bus from Joplin Bus Station to St Louis Bus Station twice daily. Tickets cost $45–90 and the journey takes 5h 30m. Alternatively, United Airlines flies from Joplin Regional Airport (JLN) to Lambert–St. Louis International Airport (STL) twice daily.

Airlines
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