There are 3 ways to get from Seneca to Knoxville by car, taxi, bus, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive 150.9 mi
best- Drive from Seneca to Knoxvillecar 150.9 mi
4h 1m$28–40Taxi, bus to Hartsfield-Jackson Atlanta International Airport, fly
- Take the taxi from Seneca to Flying J - Commercetaxi
- Take the bus from Flying J - Commerce to Atlantabus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Mcghee Tyson Airport (TYS)plane ATL - TYS
5h 50m$280–934Train to Charlotte Douglas International Airport, fly
- Take the train from Clemson Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS)plane CLT - TYS
7h 20m$216–850
Hartsfield-Jackson Atlanta International Airport (ATL) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Seneca to Knoxville is to drive which costs $27 - $40 and takes 4h 1m.
The fastest way to get from Seneca to Knoxville is to drive which takes 4h 1m and costs $27 - $40.
The distance between Seneca and Knoxville is 152 miles. The road distance is 151.8 miles.
It takes approximately 4h 1m to drive 151.8 miles from Seneca to Knoxville.
Yes, the driving distance between Seneca to Knoxville is 152 miles. It takes approximately 4h 1m to drive from Seneca to Knoxville.
There are 317+ hotels available in Knoxville.
What companies run services between Seneca, SC, USA and Knoxville, TN, USA?
You can drive from Seneca to Knoxville in around 4h 1m.
- Website
- delta.com
Flights from Hartsfield-Jackson Atlanta International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $80–600
Flights from Charlotte Douglas International Airport to Mcghee Tyson Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $110–700
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $85–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Clemson Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from Flying J - Commerce to Atlanta
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
- Ave. Duration
- 45 min
- Estimated price
- $100–130
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