There are 6 ways to get from Seneca to Myrtle Beach by taxi, plane, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Greenville–Spartanburg International Airport, fly
best- Take the taxi from Seneca to Greenville–Spartanburg International Airport (GSP)taxi
- Fly from Greenville–Spartanburg International Airport (GSP) to Myrtle Beach (MYR)plane GSP - MYR
4h 6m$443–1,282Drive 270.4 mi
cheapest- Drive from Seneca to Myrtle Beachcar 270.4 mi
5h 33m$50–72Taxi, bus
- Take the taxi from Seneca to Taqueria Guadalajara - Greenvilletaxi
- Take the bus from Taqueria Guadalajara - Greenville to Charlottebus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
10h 53m$156–219Drive to Asheville Regional Airport, fly
- Drive from Seneca to Asheville-Airport-AVLcar
- Fly from Asheville Regional Airport (AVL) to Myrtle Beach (MYR)plane AVL - MYR
5h 12m$64–313Taxi, bus to Hartsfield-Jackson Atlanta International Airport, fly
- Take the taxi from Seneca to Flying J - Commercetaxi
- Take the bus from Flying J - Commerce to Atlantabus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Myrtle Beach (MYR)plane ATL - MYR
5h 56m$303–778Train, bus
- Take the train from Clemson Amtrak Station to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
11h 3m$94–164
Greenville–Spartanburg International Airport (GSP) to Myrtle Beach (MYR) flights
Comparing Your Travel Options
The cheapest way to get from Seneca to Myrtle Beach is to drive which costs $45 - $75 and takes 5h 33m.
The fastest way to get from Seneca to Myrtle Beach is to taxi and fly which takes 4h 6m and costs $440 - $1,300.
The distance between Seneca and Myrtle Beach is 261 miles. The road distance is 271.9 miles.
The best way to get from Seneca to Myrtle Beach without a car is to taxi and bus which takes 10h 53m and costs $150 - $220.
It takes approximately 4h 6m to get from Seneca to Myrtle Beach, including transfers.
Yes, the driving distance between Seneca to Myrtle Beach is 272 miles. It takes approximately 5h 33m to drive from Seneca to Myrtle Beach.
There are 5715+ hotels available in Myrtle Beach.
What companies run services between Seneca, SC, USA and Myrtle Beach, SC, USA?
There is no direct connection from Seneca to Myrtle Beach. However, you can take the taxi to Greenville–Spartanburg International Airport (GSP) airport, fly to Myrtle Beach (MYR), then take the taxi to Myrtle Beach. Alternatively, you can take the taxi to Taqueria Guadalajara - Greenville, take the bus to Charlotte, walk to Tryon St & Mellow Dr, take the line 11 bus to Transit Center- Bay A, walk to Transit Center- Bay E, take the line 34 bus to 4th St & Graham St, walk to Charlotte Bus Station, take the bus to Camden, then take the bus to Myrtle Beach Bus Station.
- Website
- aa.com
Flights from Greenville–Spartanburg International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $45–320
Flights from Asheville Regional Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $40–280
Flights from Asheville Regional Airport to Myrtle Beach via Reagan Washington
- Ave. Duration
- 5h
- When
- Saturday
- Estimated price
- $70–370
Flights from Asheville Regional Airport to Myrtle Beach via Philadelphia
- Ave. Duration
- 5h 2m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $80–410
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Clemson Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Amtrak
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Taqueria Guadalajara - Greenville to Charlotte
- Ave. Duration
- 2h 28m
- Frequency
- Once daily
- Estimated price
- $23–45
- Schedules at
- Tornado Bus Company
- Adult
- $23–45
Bus from Flying J - Commerce to Atlanta
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- $17–40
- Schedules at
- Tornado Bus Company
- Adult
- $17–40
- Ave. Duration
- 52 min
- Estimated price
- $100–170
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide







