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How to get fromSeneca to St. Louisby taxi, plane, bus, or car

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There are 6 ways to get from Seneca to St. Louis by taxi, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Greenville–Spartanburg International Airport, fly

    best
    1. Take the taxi from Seneca to Greenville–Spartanburg International Airport (GSP)taxi taxi
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL)plane plane GSP - STL
    5h 9m
    $230–671

  2. Drive  612 mi

    cheapest
    1. Drive from Seneca to St. Louiscar car 612 mi
    11h 4m
    $105–152

  3. Taxi, bus via Carbondale

    1. Take the taxi from Seneca to Flying J - Commercetaxi taxi
    2. Take the bus from Flying J - Commerce to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    4. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    15h 39m
    $207–297

  4. Drive to Asheville Regional Airport, fly

    1. Drive from Seneca to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL)plane plane AVL - STL
    6h 14m
    $110–571

  5. Taxi, bus to Hartsfield-Jackson Atlanta International Airport, fly

    1. Take the taxi from Seneca to Flying J - Commercetaxi taxi
    2. Take the bus from Flying J - Commerce to Atlantabus bus
    3. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Lambert–St. Louis International Airport (STL)plane plane ATL - STL
    7h 2m
    $210–717

  6. Taxi, bus

    1. Take the taxi from Seneca to Flying J - Commercetaxi taxi
    2. Take the bus from Flying J - Commerce to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    16h 3m
    $212–324

Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL) flights

Calendar128Weekly Planes
Duration5h 11mAverage Duration
Ticket$88Cheapest Price
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Comparing Your Travel Options

Map of how to get from Seneca to St. Louis.ExpandLaunch map view
  • Distance: 587.7 mi
  • Duration: 5h 9m

What companies run services between Seneca, SC, USA and St. Louis, MO, USA?

There is no direct connection from Seneca to St. Louis. However, you can take the taxi to Greenville–Spartanburg International Airport (GSP) airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, then take the train to CIVIC CENTER station. Alternatively, you can take the taxi to Flying J - Commerce, take the bus to Atlanta, walk to Doraville Station, take the subway to Garnett Station, walk to Atlanta Bus Station, take the bus to Carbondale Intermodal Station, then take the bus to St Louis Bus Station.

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