Rome2Rio

How to get fromSesto Calende to Sienaby bus, train, train (Trenitalia), car, or plane

Find Transport to Siena

See all options

There are 7 ways to get from Sesto Calende to Siena by bus, train, train (Trenitalia), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Sesto Calende to Milano Centralebus bus Re4
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    5h 6m

  2. Train

    cheapest
    1. Take the train from Sesto Calende to Rho-Fiera Milanotrain train Re
    2. Take the train from Milano Rogoredo to Bologna centraletrain train
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    5h 35m
    €52–101

  3. Drive  417.7 km

    1. Drive from Sesto Calende to Sienacar car 417.7 km
    4h 14m
    €68–98

  4. Fly from Milano Malpensa Airport, train

    1. Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane plane MXP - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h 45m
    €135–274

  5. Bus via Florence

    1. Take the bus from Sesto Calende to Milano Porta Garibaldibus bus R23
    2. Take the bus from Milano - Famagosta to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    6h 43m

  6. Bus

    1. Take the bus from Sesto Calende to Rho Fiera Milanobus bus Re4 / ...
    2. Take the bus from Milano, Autostazione Lampugnano to Sienabus bus N528 / ...
    6h 45m

  7. Bus to Milan Linate Airport, fly, train

    1. Take the bus from Sesto Calende to Rho Fiera Milanobus bus
    2. Fly from Milan Linate Airport (LIN) to Florence Peretola Airport (FLR)plane plane LIN - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 19m

Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR) flights

Calendar40Weekly Planes
Duration5h 57mAverage Duration
Ticket€78Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Sesto Calende to Siena.ExpandLaunch map view
  • Distance: 438.8 km
  • Duration: 5h 6m

What companies run services between Sesto Calende, Italy and Siena, Italy?

You can take a train from Sesto Calende to Siena via Milano Rogoredo, Bologna Centrale, and Firenze S.M.N. in around 5h 35m. Alternatively, you can take a bus from Sesto Calende to Siena via Milan Porta Garibaldi, Garibaldi Fs, Famagosta, Milano - Famagosta, and Florence Villa Constanza Bus Station in around 6h 43m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

Booking & Getting There