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How to get fromSesto Calende to Sienaby train (Trenitalia), bus, car, plane, or train

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There are 6 ways to get from Sesto Calende to Siena by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Bologna

    best
    1. Take the train from Sesto Calende to Rho-Fiera Milanotrain train Re
    2. Take the train from Milano Rogoredo to Bologna centraletrain train
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    5h 24m
    €54–120

  2. Bus

    1. Take the bus from Sesto Calende to Milano Centralebus bus Re4
    2. Take the bus from Milano - Famagosta to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    7h 55m

  3. Drive 417.7 km

    1. Drive from Sesto Calende to Sienacar car 417.7 km
    4h 14m
    €66–95

  4. Fly, train

    1. Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane plane MXP - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h 38m
    €105–223

  5. Bus, train

    1. Take the bus from Sesto Calende to Rho Fiera Milanobus bus Re4 / ...
    2. Take the train from Rho-Fiera Milano to Florence Santa Maria Novellatrain train
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    5h 31m

  6. Train (Trenitalia)

    1. Take the train from Sesto Calende to Rho-Fiera Milanotrain train Re
    2. Take the train from Rho-Fiera Milano to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    6h 2m
    €62–123

Sesto Calende to Siena by train

Calendar115Weekly Trains
Duration5h 24mAverage Duration
Ticket€54Cheapest Price
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Questions & Answers

Map of how to get from Sesto Calende to Siena.ExpandLaunch map view
  • Distance: 452.9 km
  • Duration: 5h 24m

What companies run services between Sesto Calende, Italy and Siena, Italy?

You can take a train from Sesto Calende to Siena via Milano Rogoredo, Bologna Centrale, and Firenze S.M.N. in around 5h 24m. Alternatively, you can take a bus from Sesto Calende to Siena via Milano Centrale, Milano, Stazione Centrale, famagosta m2, Milano - Famagosta, and Florence Villa Constanza Bus Station in around 7h 55m.

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