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How to get fromSeymour to Niagara Fallsby bus, train, car, or plane

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There are 8 ways to get from Seymour to Niagara Falls by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train via Toledo

    best
    1. Take the bus from TA Travel Center - Seymour to Indianapolisbus bus
    2. Take the bus from Indianapolis, IN to Toledobus bus
    3. Take the train from Toledo to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    15h 50m
    $173–575

  2. Drive 534.1 mi

    cheapest
    1. Drive from Seymour to Niagara Fallscar car 534.1 mi
    9h 33m
    $98–141

  3. Bus

    1. Take the bus from TA Travel Center - Seymour to Indianapolisbus bus
    2. Take the bus from Indianapolis Union Station to Cincinnati Bus Stationbus bus
    3. Take the bus from Cincinnati, OH to Buffalo, NYbus bus
    17h 11m
    $130–347

  4. Bus to Indianapolis, fly to Buffalo Niagara International Airport, bus

    1. Take the bus from TA Travel Center - Seymour to Indianapolisbus bus
    2. Fly from Indianapolis (IND) to Buffalo Niagara International Airport (BUF)plane plane IND - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    9h 35m
    $189–874

  5. Bus via Pittsburgh

    1. Take the bus from TA Travel Center - Seymour to Indianapolisbus bus
    2. Take the bus from Indianapolis to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    20h 32m
    $180–457

  6. Bus, train

    1. Take the bus from TA Travel Center - Seymour to Indianapolisbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    21h 56m
    $287–775

  7. Bus to Louisville International Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the bus from TA Travel Center - Seymour to El Mercadito Grocery - Clarksville, INbus bus
    2. Fly from Louisville International Airport (SDF) to Buffalo Niagara International Airport (BUF)plane plane SDF - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    10h 3m
    $197–926

  8. Bus to Indianapolis, fly to Toronto Pearson International Airport, bus

    1. Take the bus from TA Travel Center - Seymour to Indianapolisbus bus
    2. Fly from Indianapolis (IND) to Toronto Pearson International Airport (YYZ)plane plane IND - YYZ
    3. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    10h 10m
    $485–1,201

Indianapolis (IND) to Buffalo Niagara International Airport (BUF) flights

Calendar100Weekly Planes
Duration4h 26mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Seymour to Niagara Falls.ExpandLaunch map view
  • Distance: 628.6 mi
  • Duration: 15h 50m

What companies run services between Seymour, IN, USA and Niagara Falls, NY, USA?

You can take a vehicle from Seymour to Main Street & Pine Avenue via TA Travel Center - Seymour, Indianapolis, Lafayette Rd & Office Plaza Blvd, Ctc-R, Indianapolis Union Station, Cincinnati Bus Station, Cincinnati, OH, and Ellicott Street & MTC Static in around 17h 11m.

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