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How to get fromSeymour to St. Louisby bus (Greyhound), car, bus, or plane

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There are 5 ways to get from Seymour to St. Louis by bus (Greyhound), car, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from TA Travel Center - Seymour to Indianapolisbus bus Memphis
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    7h 27m
    $83–220

  2. Drive 253 mi

    cheapest
    1. Drive from Seymour to St. Louiscar car 253 mi
    5h 47m
    $47–67

  3. Bus to Indianapolis, fly

    1. Take the bus from TA Travel Center - Seymour to Indianapolisbus bus
    2. Fly from Indianapolis (IND) to Lambert–St. Louis International Airport (STL)plane plane IND - STL
    8h 18m
    $153–750

  4. Bus to Louisville International Airport, fly

    1. Take the bus from TA Travel Center - Seymour to El Mercadito Grocery - Clarksville, INbus bus
    2. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane plane SDF - STL
    8h 36m
    $151–752

  5. Bus to Nashville, fly

    1. Take the bus from TA Travel Center - Seymour to Tornado Bus Co - Nashvillebus bus
    2. Fly from Nashville (BNA) to Lambert–St. Louis International Airport (STL)plane plane BNA - STL
    8h 44m
    $155–652

Indianapolis (IND) to Lambert–St. Louis International Airport (STL) flights

Calendar121Weekly Planes
Duration4h 14mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Seymour to St. Louis.ExpandLaunch map view
  • Distance: 323.6 mi
  • Duration: 7h 27m

What companies run services between Seymour, IN, USA and St. Louis, MO, USA?

You can take a vehicle from Seymour to St Louis Bus Station via TA Travel Center - Seymour, Indianapolis, Lafayette Rd & Office Plaza Blvd, Ctc-R, and Indianapolis Union Station in around 7h 27m.

Airlines
Bus operators

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