There are 6 ways to get from Sheboygan to Mayo Clinic by bus (Greyhound), car, bus, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Sheboygan to Milwaukee Intermodal Stationbus Greyhound US0150S
- Take the bus from Milwaukee to Rochesterbus Jefferson Lines 966
7h 48m$81–125Drive 258.9 mi
cheapest- Drive from Sheboygan to Mayo Cliniccar 258.9 mi
5h 5m$48–69Bus to General Mitchell International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Sheboygan to Milwaukee Intermodal Stationbus
- Fly from General Mitchell International Airport (MKE) to Minneapolis–Saint Paul International Airport (MSP)plane MKE - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 3m$663–1,089Bus to Green Bay, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Sheboygan to Green Bay Transit Centerbus
- Fly from Green Bay (GRB) to Minneapolis–Saint Paul International Airport (MSP)plane GRB - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 2m$152–502Bus, bus to Chicago O'Hare International Airport, fly to Rochester
- Take the bus from Sheboygan to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane ORD - RST
7h 25m$90–377Bus, taxi to Appleton International Airport, fly to Minneapolis–Saint Paul International Airport
- Take the bus from Sheboygan to Green Bay Transit Centerbus
- Take the taxi from Green Bay Transit Center to Appleton International Airport (ATW)taxi
- Fly from Appleton International Airport (ATW) to Minneapolis–Saint Paul International Airport (MSP)plane ATW - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 33m$257–627
Sheboygan to Mayo Clinic by bus and foot
Comparing Your Travel Options
The cheapest way to get from Sheboygan to Mayo Clinic is to drive which costs $45 - $70 and takes 5h 5m.
The fastest way to get from Sheboygan to Mayo Clinic is to drive which takes 5h 5m and costs $45 - $70.
No, there is no direct bus from Sheboygan to Mayo Clinic. However, there are services departing from Sheboygan and arriving at Rochester via Milwaukee. The journey, including transfers, takes approximately 7h 48m.
The distance between Sheboygan and Mayo Clinic is 335 miles. The road distance is 260.4 miles.
The best way to get from Sheboygan to Mayo Clinic without a car is to bus which takes 7h 48m and costs $80 - $130.
It takes approximately 7h 48m to get from Sheboygan to Mayo Clinic, including transfers.
Sheboygan to Mayo Clinic bus services, operated by Greyhound USA, depart from Sheboygan station.
Sheboygan to Mayo Clinic bus services, operated by Greyhound USA, arrive at Milwaukee Intermodal Station.
Yes, the driving distance between Sheboygan to Mayo Clinic is 260 miles. It takes approximately 5h 5m to drive from Sheboygan to Mayo Clinic.
There are 77+ hotels available in Mayo Clinic.
What companies run services between Sheboygan, WI, USA and Mayo Clinic, MN, USA?
You can take a bus from Sheboygan to Mayo Clinic via Milwaukee Intermodal Station, Milwaukee, and Rochester in around 7h 48m.
- Website
- delta.com
Flights from General Mitchell International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $80–550
Flights from Green Bay to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $55–380
Flights from Appleton International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $55–380
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $40–270
- Website
- southwest.com
Flights from General Mitchell International Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 3h 12m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–600
- Website
- suncountry.com
Flights from General Mitchell International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 19m
- When
- Sunday
- Estimated price
- $80–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Sheboygan to Milwaukee Intermodal Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Sheboygan to Milwaukee Intermodal Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Sheboygan to Green Bay Transit Center
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $10–16
- Website
- Greyhound
Bus from Sheboygan to Milwaukee Intermodal Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Sheboygan to Green Bay Transit Center
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $10–16
- Website
- Greyhound
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Sheboygan to Milwaukee Intermodal Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $10–26
- Website
- Indian Trails
Bus from Sheboygan to Milwaukee Intermodal Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $10–26
- Website
- Indian Trails
Bus from Sheboygan to Green Bay Transit Center
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $12–28
- Website
- Indian Trails
Bus from Sheboygan to Milwaukee Intermodal Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $10–26
- Website
- Indian Trails
Bus from Sheboygan to Green Bay Transit Center
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $12–28
- Website
- Indian Trails
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
- Ave. Duration
- 41 min
- Estimated price
- $140–170
Yellow Cab Green Bay
- Phone
- +1-920-435-1111
- Website
- yellowcabgreenbay.com
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