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How to get fromSheboygan to Mayo Clinicby bus (Greyhound), car, bus, plane, or taxi

Find Transport to Mayo Clinic

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There are 6 ways to get from Sheboygan to Mayo Clinic by bus (Greyhound), car, bus, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Sheboygan to Milwaukee Intermodal Stationbus bus Greyhound US0150S
    2. Take the bus from Milwaukee to Rochesterbus bus Jefferson Lines 966
    7h 48m
    $81–125
  2. Drive  258.9 mi

    cheapest
    1. Drive from Sheboygan to Mayo Cliniccar car 258.9 mi
    5h 5m
    $48–69
  3. Bus to General Mitchell International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Sheboygan to Milwaukee Intermodal Stationbus bus
    2. Fly from General Mitchell International Airport (MKE) to Minneapolis–Saint Paul International Airport (MSP)plane plane MKE - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 3m
    $663–1,089
  4. Bus to Green Bay, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Sheboygan to Green Bay Transit Centerbus bus
    2. Fly from Green Bay (GRB) to Minneapolis–Saint Paul International Airport (MSP)plane plane GRB - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 2m
    $152–502
  5. Bus, bus to Chicago O'Hare International Airport, fly to Rochester

    1. Take the bus from Sheboygan to Milwaukee Intermodal Stationbus bus
    2. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    3. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    7h 25m
    $90–377
  6. Bus, taxi to Appleton International Airport, fly to Minneapolis–Saint Paul International Airport

    1. Take the bus from Sheboygan to Green Bay Transit Centerbus bus
    2. Take the taxi from Green Bay Transit Center to Appleton International Airport (ATW)taxi taxi
    3. Fly from Appleton International Airport (ATW) to Minneapolis–Saint Paul International Airport (MSP)plane plane ATW - MSP
    4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 33m
    $257–627

Sheboygan to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration7h 48mAverage Duration
Ticket$81Cheapest Price
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Comparing Your Travel Options

What companies run services between Sheboygan, WI, USA and Mayo Clinic, MN, USA?

You can take a bus from Sheboygan to Mayo Clinic via Milwaukee Intermodal Station, Milwaukee, and Rochester in around 7h 48m.

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Need to know: Greyhound

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