There are 13 ways to get from Sicily to Isernia by plane, train, ferry, car, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Vincenzo Magliocco Airport to Fiumicino International Airport, train
best- Fly from Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO)plane CIY - FCO
- Take the train from Roma Termini to Iserniatrain
5h 15m€89–293Bus via Caserta
cheapest- Take the bus from Palermo Terminal Bus to Caserta pzza Garibaldibus Autoservizi Salemi S202
- Take the bus from Caserta Terminal Bus to Iserniabus 433
13h 24m€37–56Ferry, drive
- Take the ferry from Port of Palermo to Naples Beverelloferry
- Drive from Naples Beverello to Iserniacar
10h 5m€47–81Train, ferry
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Iserniatrain Re
12h 16mFly Catania–Fontanarossa Airport to Naples Airport, train
- Fly from Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP)plane CTA - NAP
- Take the train from Caserta to Iserniatrain
5h 49m€45–177Fly Palermo Airport to Naples Airport, train
- Fly from Palermo Airport (PMO) to Naples Airport (NAP)plane PMO - NAP
- Take the train from Caserta to Iserniatrain
6h 21m€43–179Fly Catania–Fontanarossa Airport to Fiumicino International Airport, train
- Fly from Catania–Fontanarossa Airport (CTA) to Fiumicino International Airport (FCO)plane CTA - FCO
- Take the train from Roma Termini to Iserniatrain
6h 7m€55–161Fly Palermo Airport to Fiumicino International Airport, train
- Fly from Palermo Airport (PMO) to Fiumicino International Airport (FCO)plane PMO - FCO
- Take the train from Roma Termini to Iserniatrain
6h 39m€51–173Fly Trapani Airport to Fiumicino International Airport, train
- Fly from Trapani Airport (TPS) to Fiumicino International Airport (FCO)plane TPS - FCO
- Take the train from Roma Termini to Iserniatrain
6h 25m€70–220Fly Catania–Fontanarossa Airport to Abruzzo Airport, bus
- Fly from Catania–Fontanarossa Airport (CTA) to Abruzzo Airport (PSR)plane CTA - PSR
- Take the bus from Pescara to Iserniabus
7h 28m€47–175Fly Trapani Airport to Abruzzo Airport, bus
- Fly from Trapani Airport (TPS) to Abruzzo Airport (PSR)plane TPS - PSR
- Take the bus from Pescara to Iserniabus
7h 36m€51–244Train (Trenitalia)
- Take the train from Palermo Centrale to Napoli Centraletrain Ic
- Take the train from Napoli Centrale to Iserniatrain Re
13h 28m€82–178Bus
- Take the bus from Palermo Piazza Cairoli to Casello - A1 Ingresso Caianellobus
- Take the bus from Casello - A1 Ingresso Caianello to Iserniabus 6
19h 19m
Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO) flights
Questions & Answers
The cheapest way to get from Sicily to Isernia is to bus via Caserta which costs €35 - €60 and takes 13h 24m.
The fastest way to get from Sicily to Isernia is to fly and train which takes 5h 15m and costs €85 - €300.
No, there is no direct bus from Sicily to Isernia. However, there are services departing from Piazza Boiardo and arriving at Isernia via Palermo Terminal Bus and Caserta Terminal Bus. The journey, including transfers, takes approximately 13h 24m.
No, there is no direct train from Sicily to Isernia. However, there are services departing from Palermo Notarbartolo and arriving at Isernia via Palermo Centrale and Napoli Centrale. The journey, including transfers, takes approximately 13h 28m.
The distance between Sicily and Isernia is 801 km.
The best way to get from Sicily to Isernia without a car is to train and ferry which takes 12h 16m and costs .
It takes approximately 5h 15m to get from Sicily to Isernia, including transfers.
Sicily to Isernia bus services, operated by Autoservizi Salemi Srl, depart from Palermo Terminal Bus station.
Sicily to Isernia train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Sicily to Isernia is to bus via Caserta which takes 13h 24m and costs €35 - €60. Alternatively, you can train, which costs €80 - €180 and takes 13h 28m.
What companies run services between Sicily, Italy and Isernia, Italy?
You can take a bus from Piazza Boiardo to Isernia via Stazione Centrale Pensilina Esterna, Palermo Terminal Bus, Caserta pzza Garibaldi, and Caserta Terminal Bus in around 13h 24m. Alternatively, you can take a train from Palermo Notarbartolo to Isernia via Palermo Centrale and Napoli Centrale in around 13h 28m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Naples Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €25–130
Flights from Palermo Airport to Naples Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €27–160
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €23–85
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport via Bari
- Ave. Duration
- 2h 45m
- When
- Saturday
- Estimated price
- €23–85
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport via Malta
- Ave. Duration
- 3h 15m
- When
- Sunday
- Estimated price
- €23–85
Flights from Palermo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €26–110
Flights from Trapani Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–170
Flights from Catania–Fontanarossa Airport to Abruzzo Airport
- Ave. Duration
- 1h 25m
- When
- Saturday, Sunday, Wednesday, Tuesday, and Thursday
- Estimated price
- €30–140
Flights from Trapani Airport to Abruzzo Airport
- Ave. Duration
- 1h 10m
- When
- Friday, Sunday, Thursday, and Wednesday
- Estimated price
- €40–220
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €45–100
Flights from Palermo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €45–120
- Website
- aeroitalia.com
Flights from Vincenzo Magliocco Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €40–600
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €23–320
Flights from Palermo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €21–350
- Website
- flexflight.dk
Flights from Vincenzo Magliocco Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €40–600
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €23–320
Flights from Palermo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €21–350
- Website
- volotea.com
Flights from Palermo Airport to Naples Airport
- Ave. Duration
- 1h
- When
- Friday and Sunday
- Estimated price
- €19–90
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €45–100
Flights from Palermo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €45–120
- Website
- easyjet.com
Flights from Catania–Fontanarossa Airport to Naples Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- €25–140
Flights from Palermo Airport to Naples Airport
- Ave. Duration
- 59 min
- When
- Every day
- Estimated price
- €27–150
- Website
- flyulendo.com
Flights from Palermo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €15–75
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €27–45
- Website
- Trenitalia
Train from Napoli Afragola to Isernia
- Ave. Duration
- 1h 49m
- Frequency
- Every 4 hours
- Estimated price
- €14–24
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- €16–27
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- €23–50
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Napoli Centrale
- Ave. Duration
- 9h 6m
- Frequency
- 4 times a day
- Estimated price
- €65–150
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 4m
- Frequency
- Hourly
- Estimated price
- €60–130
- Schedules at
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 5h 3m
- Frequency
- Twice daily
- Estimated price
- €50–110
- Website
- Italo Treno
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Palermo Terminal Bus to Caserta pzza Garibaldi
- Ave. Duration
- 9h 50m
- Frequency
- Twice daily
- Estimated price
- €30–45
- Schedules at
- autoservizisalemi.it
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Caserta Terminal Bus to Isernia
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €6–10
- Website
- Flixbus
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €11–19
- Website
- Flixbus
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €11–19
- Website
- Flixbus
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 20m
- Frequency
- 6 times a week
- Estimated price
- €7–11
- Schedules at
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 20m
- Frequency
- 6 times a week
- Estimated price
- €7–11
- Schedules at
- atm-molise.it
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Palermo Piazza Cairoli to Casello - A1 Ingresso Caianello
- Ave. Duration
- 15h 59m
- Frequency
- Twice a week
- Website
- Onebus
- Phone
- 0865.221788
- [email protected]
- Website
- satiautobus.com
Bus from Casello - A1 Ingresso Caianello to Isernia
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
- Phone
- +39.081.496.444
- [email protected]
- Website
- Grimaldi Lines
Ferry from Port of Palermo to Naples Beverello
- Ave. Duration
- 8h 30m
- Frequency
- 6 times a week
- Estimated price
- €30–55
- Website
- Grimaldi Lines
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
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More Questions & Answers
Sicily to Isernia bus services, operated by Autoservizi Salemi Srl, arrive at Caserta pzza Garibaldi station.
Sicily to Isernia train services, operated by Trenitalia Intercity, arrive at Napoli Centrale station.
Book your Sicily to Isernia train tickets online with Omio.
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