There are 9 ways to get from Sicily to Karlsruhe by plane, train, train (Trenitalia), car ferry, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Catania–Fontanarossa Airport to Stuttgart Airport, train
best- Fly from Catania–Fontanarossa Airport (CTA) to Stuttgart Airport (STR)plane CTA - STR
- Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
5h 56m€90–324Train
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
23h 53m€266–481Car ferry, drive
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Karlsruhecar
27h 23m€201–311Bus
- Take the bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Stationbus
34h 24m€261–371Fly Palermo Airport to Stuttgart Airport, train
- Fly from Palermo Airport (PMO) to Stuttgart Airport (STR)plane PMO - STR
- Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
6h 28m€90–345Fly Catania–Fontanarossa Airport to Frankfurt, train
- Fly from Catania–Fontanarossa Airport (CTA) to Frankfurt (FRA)plane CTA - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
6h 40m€98–274Fly Palermo Airport to Frankfurt, train
- Fly from Palermo Airport (PMO) to Frankfurt (FRA)plane PMO - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
7h 12m€98–275Fly Palermo Airport to Zurich Airport, train
- Fly from Palermo Airport (PMO) to Zurich Airport (ZRH)plane PMO - ZRH
- Take the train from Zürich HB to Basel SBBtrain
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
8h 31m€147–409Bus via Milan
- Take the bus from Palermo to Milano, Autostazione Lampugnanobus N597
- Take the bus from Milano, Autostazione Lampugnano to Karlsruhe central train stationbus N77
34h 25m€191–291
Sicily to Karlsruhe by train
Comparing Your Travel Options
The cheapest way to get from Sicily to Karlsruhe is to fly and train which costs €90 - €330 and takes 5h 56m.
The fastest way to get from Sicily to Karlsruhe is to fly and train which takes 5h 56m and costs €90 - €330.
No, there is no direct bus from Sicily to Karlsruhe station. However, there are services departing from Piazza Boiardo and arriving at Karlsruhe Central Bus Station via Palermo Piazza Cairoli. The journey, including transfers, takes approximately 34h 24m.
No, there is no direct train from Sicily to Karlsruhe. However, there are services departing from Palermo Notarbartolo and arriving at Karlsruhe Hbf via Palermo Centrale, Roma Termini and Milano Centrale. The journey, including transfers, takes approximately 23h 53m.
The distance between Sicily and Karlsruhe is 1435 km.
The best way to get from Sicily to Karlsruhe without a car is to train which takes 23h 53m and costs €260 - €490.
It takes approximately 5h 56m to get from Sicily to Karlsruhe, including transfers.
Sicily to Karlsruhe bus services, operated by Onebus, depart from Palermo Piazza Cairoli station.
Sicily to Karlsruhe train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Sicily to Karlsruhe is to train which takes 23h 53m and costs €260 - €490. Alternatively, you can bus, which costs €260 - €380 and takes 34h 24m.
What companies run services between Sicily, Italy and Karlsruhe, Germany?
You can take a train from Palermo Notarbartolo to Karlsruhe Hbf via Palermo Centrale, Roma Termini, and Milano Centrale in around 23h 53m. Alternatively, Onebus operates a bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Station once a week. Tickets cost €260–370 and the journey takes 32h 59m.
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Stuttgart Airport via Milan Linate
- Ave. Duration
- 4h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €85–280
Flights from Palermo Airport to Stuttgart Airport via Milan Linate
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €100–340
Flights from Palermo Airport to Stuttgart Airport via Rome
- Ave. Duration
- 3h 55m
- When
- Saturday and Sunday
- Estimated price
- €65–260
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 30m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €80–290
Flights from Catania–Fontanarossa Airport to Frankfurt via Munich
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €85–300
Flights from Catania–Fontanarossa Airport to Frankfurt via Milan Linate
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- €70–230
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €100–360
Flights from Palermo Airport to Frankfurt via Milan Linate
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- €100–200
- Website
- lufthansa.com
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 30m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €80–290
Flights from Catania–Fontanarossa Airport to Frankfurt via Munich
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €60–300
Flights from Palermo Airport to Frankfurt
- Ave. Duration
- 2h 20m
- When
- Thursday to Sunday
- Estimated price
- €100–360
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €100–360
- Website
- swiss.com
Flights from Catania–Fontanarossa Airport to Frankfurt via Zurich Airport
- Ave. Duration
- 4h 55m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €55–300
Flights from Palermo Airport to Zurich Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- €90–360
- Website
- eurowings.com
Flights from Catania–Fontanarossa Airport to Stuttgart Airport
- Ave. Duration
- 2h 15m
- When
- Saturday, Sunday, Tuesday, Wednesday, and Thursday
- Estimated price
- €65–220
Flights from Palermo Airport to Stuttgart Airport
- Ave. Duration
- 2h 5m
- When
- Sunday
- Estimated price
- €65–260
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €19–27
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €19–27
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–75
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €15–65
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €15–65
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €35–150
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 19m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €75–140
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 50m
- Frequency
- Every 4 hours
- Estimated price
- €65–110
- Website
- Italo Treno
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Karlsruhe Hbf
- Ave. Duration
- 6h 17m
- Frequency
- Once daily
- Estimated price
- €110–170
- Website
- Trenitalia Eurocity
- 1st Class
- €110–170
- 2nd Class
- €110–150
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- €14–28
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- €14–28
- Website
- Nederlandse Spoorwegen (NS)
Train from Zürich HB to Basel SBB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €30–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Station
- Ave. Duration
- 32h 59m
- Frequency
- Once a week
- Estimated price
- €260–370
- Website
- Onebus
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 22h 20m
- Frequency
- Once daily
- Estimated price
- €140–210
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Karlsruhe central train station
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- €50–80
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
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Booking & Getting There
Sicily to Karlsruhe bus services, operated by Onebus, arrive at Karlsruhe Central Bus Station.
Sicily to Karlsruhe train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Sicily to Karlsruhe train tickets online with Omio.
There are 894+ hotels available in Karlsruhe.



















































