There are 10 ways to get from Sicily to Karlsruhe by plane, train, train (Trenitalia), car ferry, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Catania–Fontanarossa Airport to Stuttgart Airport, train
best- Fly from Catania–Fontanarossa Airport (CTA) to Stuttgart Airport (STR)plane CTA - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
5h 54m€85–274Fly Catania–Fontanarossa Airport to Allgäu Airport, Memmingen, train
cheapest- Fly from Catania–Fontanarossa Airport (CTA) to Allgäu Airport, Memmingen (FMM)plane CTA - FMM
- Take the train from Memmingen, Bahnhof ZOB to Ulm Hauptbahnhoftrain
- Take the train from Ulm Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
8h 22m€71–286Train
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Basel Sbbtrain Ec
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain 12 / ...
23h 28m€257–526Car ferry, drive
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Karlsruhecar
26h 8m€221–331Bus
- Take the bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Stationbus
34h 24m€261–371Fly Palermo Airport to Stuttgart Airport, train
- Fly from Palermo Airport (PMO) to Stuttgart Airport (STR)plane PMO - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
6h 26m€90–295Fly Catania–Fontanarossa Airport to Frankfurt, train
- Fly from Catania–Fontanarossa Airport (CTA) to Frankfurt (FRA)plane CTA - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
6h 40m€105–269Fly Palermo Airport to Frankfurt, train
- Fly from Palermo Airport (PMO) to Frankfurt (FRA)plane PMO - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
7h 12m€100–270Fly Catania–Fontanarossa Airport to Hahn, bus, train
- Fly from Catania–Fontanarossa Airport (CTA) to Hahn (HHN)plane CTA - HHN
- Take the bus from Hahn to Mainz, Hauptbahnhofbus
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
8h 12m€101–551Bus via Milan
- Take the bus from Palermo to Milano, Autostazione Lampugnanobus N597
- Take the bus from Milano, Autostazione Lampugnano to Karlsruhe central train stationbus N77
34h 25m€191–301
Sicily to Karlsruhe by train
Comparing Your Travel Options
The cheapest way to get from Sicily to Karlsruhe is to fly and train which costs €70 - €290 and takes 8h 22m.
The fastest way to get from Sicily to Karlsruhe is to fly and train which takes 5h 54m and costs €85 - €280.
No, there is no direct bus from Sicily to Karlsruhe station. However, there are services departing from Piazza Boiardo and arriving at Karlsruhe Central Bus Station via Palermo Piazza Cairoli. The journey, including transfers, takes approximately 34h 24m.
No, there is no direct train from Sicily to Karlsruhe. However, there are services departing from Palermo Notarbartolo and arriving at Karlsruhe Hauptbahnhof via Palermo Centrale, Roma Termini, Milano Centrale and Basel SBB. The journey, including transfers, takes approximately 23h 28m.
The distance between Sicily and Karlsruhe is 1435 km.
The best way to get from Sicily to Karlsruhe without a car is to train which takes 23h 28m and costs €250 - €550.
It takes approximately 5h 54m to get from Sicily to Karlsruhe, including transfers.
Sicily to Karlsruhe bus services, operated by FlixBus, depart from Palermo station.
Sicily to Karlsruhe train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Sicily to Karlsruhe is to train which takes 23h 28m and costs €250 - €550. Alternatively, you can bus, which costs €260 - €380 and takes 34h 24m.
What companies run services between Sicily, Italy and Karlsruhe, Germany?
You can take a train from Palermo Notarbartolo to Karlsruhe Hauptbahnhof via Palermo Centrale, Roma Termini, Milano Centrale, and Basel SBB in around 23h 28m. Alternatively, Onebus operates a bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Station once a week. Tickets cost €260–370 and the journey takes 32h 59m.
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Stuttgart Airport via Milan Linate
- Ave. Duration
- 4h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–290
Flights from Palermo Airport to Stuttgart Airport via Milan Linate
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €110–360
Flights from Palermo Airport to Stuttgart Airport via Rome
- Ave. Duration
- 3h 55m
- When
- Sunday
- Estimated price
- €65–260
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 30m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €80–300
Flights from Catania–Fontanarossa Airport to Frankfurt via Milan Linate
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- €70–230
Flights from Palermo Airport to Frankfurt via Milan Linate
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- €95–200
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Allgäu Airport, Memmingen
- Ave. Duration
- 2h 10m
- When
- Monday, Friday, and Saturday
- Estimated price
- €35–230
Flights from Catania–Fontanarossa Airport to Allgäu Airport, Memmingen via Rome
- Ave. Duration
- 4h 40m
- When
- Saturday and Monday
- Estimated price
- €35–230
Flights from Catania–Fontanarossa Airport to Hahn
- Ave. Duration
- 2h 35m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €70–310
Flights from Catania–Fontanarossa Airport to Hahn via Rome
- Ave. Duration
- 4h 20m
- When
- Monday and Saturday
- Estimated price
- €70–310
- Website
- lufthansa.com
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 30m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €80–300
Flights from Catania–Fontanarossa Airport to Frankfurt via Munich
- Ave. Duration
- 4h 10m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €85–300
Flights from Palermo Airport to Frankfurt
- Ave. Duration
- 2h 20m
- When
- Thursday and Saturday
- Estimated price
- €100–370
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 4h 45m
- When
- Friday
- Estimated price
- €100–370
- Website
- eurowings.com
Flights from Catania–Fontanarossa Airport to Stuttgart Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €65–230
Flights from Palermo Airport to Stuttgart Airport
- Ave. Duration
- 2h 5m
- When
- Wednesday and Saturday
- Estimated price
- €65–260
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Allgäu Airport, Memmingen
- Ave. Duration
- 2h 15m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €30–180
Flights from Catania–Fontanarossa Airport to Hahn via Tirana
- Ave. Duration
- 5h 45m
- When
- Monday, Friday, and Sunday
- Estimated price
- €65–310
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €21–45
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €21–45
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Memmingen, Bahnhof ZOB to Ulm Hauptbahnhof
- Ave. Duration
- 31 min
- Frequency
- Twice daily
- Estimated price
- €8–17
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Ulm Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 32m
- Frequency
- Every 4 hours
- Estimated price
- €27–55
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €11–22
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 22 min
- Frequency
- Hourly
- Estimated price
- €9–19
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 28m
- Frequency
- Once daily
- Estimated price
- €9–13
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €21–30
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 28m
- Frequency
- Once daily
- Estimated price
- €9–13
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Memmingen, Bahnhof ZOB to Ulm Hauptbahnhof
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–9
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 57 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–10
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 19m
- Frequency
- 4 times a day
- Estimated price
- €95–170
- Website
- Trenitalia Intercity
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 15m
- Frequency
- Every 30 minutes
- Estimated price
- €75–130
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 4h 42m
- Frequency
- Every 4 hours
- Estimated price
- €65–110
- Website
- Italo Treno
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Basel Sbb
- Ave. Duration
- 4h 21m
- Frequency
- Every 2 hours
- Estimated price
- €75–130
- Website
- Trenitalia Eurocity
- 1st Class
- €90–130
- 2nd Class
- €75–110
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 43m
- Frequency
- Twice daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 6m
- Frequency
- 5 times a week
- Estimated price
- €13–19
- Schedules at
- Süwex
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 42 min
- Frequency
- Twice daily
- Estimated price
- €16
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 6131 4975 022
- [email protected]
- Website
- dbregiobus-mitte.de
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once a week
- Estimated price
- €13–19
- Schedules at
- dbregiobus-mitte.de
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Station
- Ave. Duration
- 32h 59m
- Frequency
- Once a week
- Estimated price
- €260–370
- Website
- Onebus
- Phone
- +49 (0) 6543 5019-400
- [email protected]
- Website
- Bohr
Bus from Hahn to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €14–16
- Schedules at
- Bohr
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 22h 20m
- Frequency
- Once daily
- Estimated price
- €140–220
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Karlsruhe central train station
- Ave. Duration
- 9h 45m
- Frequency
- Twice daily
- Estimated price
- €50–80
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
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Booking & Getting There
Sicily to Karlsruhe bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Sicily to Karlsruhe train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Sicily to Karlsruhe train tickets online with Omio.
Book your Sicily to Karlsruhe bus tickets online with 12go.asia.
There are 897+ hotels available in Karlsruhe.

















































