There are 8 ways to get from Sicily to Luxembourg by plane, car ferry, car, train (Trenitalia, TGV), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Catania–Fontanarossa Airport
best- Fly from Catania–Fontanarossa Airport (CTA) to Luxembourg (LUX)plane CTA - LUX
4h 39m€74–264Fly from Palermo Airport
cheapest- Fly from Palermo Airport (PMO) to Luxembourg (LUX)plane PMO - LUX
5h 21m€59–295Car ferry, drive
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Luxembourgcar
28h 4m€241–361Train
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Sestri Levantetrain Ic
- Take the train from Sestri Levante to Zuerich Hbtrain Ec
- Take the train from Zürich HB to Mulhousetrain Tgv
- Take the train from Mulhouse Ville to Luxembourgtrain Tgv
32h 3m€301–531Bus
- Take the bus from Palermo Piazza Cairoli to Luxembourg Park&Drivebus
35h 11m€291–401Fly from Trapani Airport
- Fly from Trapani Airport (TPS) to Luxembourg (LUX)plane TPS - LUX
6h 47m€103–453Car ferry, train
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Take the train from Genova P.Za Principe to Zuerich Hbtrain Ec
- Take the train from Zürich HB to Mulhousetrain Tgv
- Take the train from Mulhouse Ville to Luxembourgtrain Tgv
33h 53m€281–451Bus via Aosta
- Take the bus from Palermo to Aostabus N597
- Take the bus from Aosta to Luxembourg, P+R Bouillonbus FlixBus N506
37h 20m€216–336
Sicily to Luxembourg by train
Comparing Your Travel Options
The cheapest way to get from Sicily to Luxembourg is to fly which costs €55 - €300 and takes 5h 21m.
The fastest way to get from Sicily to Luxembourg is to fly which takes 4h 39m and costs €70 - €270.
No, there is no direct bus from Sicily to Luxembourg. However, there are services departing from Piazza Boiardo and arriving at Luxembourg Park&Drive via Palermo Piazza Cairoli. The journey, including transfers, takes approximately 35h 11m.
No, there is no direct train from Sicily to Luxembourg. However, there are services departing from Palermo Notarbartolo and arriving at Luxembourg via Palermo Centrale, Roma Termini, Sestri Levante, Zürich HB and Mulhouse Ville. The journey, including transfers, takes approximately 32h 3m.
The distance between Sicily and Luxembourg is 1535 km.
The best way to get from Sicily to Luxembourg without a car is to train which takes 32h 3m and costs €300 - €550.
It takes approximately 4h 39m to get from Sicily to Luxembourg, including transfers.
Sicily to Luxembourg bus services, operated by Onebus, depart from Palermo Piazza Cairoli station.
Sicily to Luxembourg train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Sicily to Luxembourg is to fly which takes 4h 39m and costs €70 - €270. Alternatively, you can train, which costs €300 - €550 and takes 32h 3m, you could also bus, which costs €290 - €410 and takes 35h 11m.
What companies run services between Sicily, Italy and Luxembourg?
Luxair, ITA Airways, and three other airlines fly from Catania–Fontanarossa Airport (CTA) to Luxembourg (LUX) once daily. Alternatively, you can take a train from Palermo Notarbartolo to Luxembourg via Palermo Centrale, Roma Termini, Sestri Levante, Zuerich Hb, Zürich HB, Mulhouse, and Mulhouse Ville in around 32h 3m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Luxembourg via Milan Bergamo
- Ave. Duration
- 5h 6m
- When
- Tuesday and Sunday
- Estimated price
- €55–260
Flights from Palermo Airport to Luxembourg via Milan Bergamo
- Ave. Duration
- 4h 57m
- When
- Saturday, Monday, Thursday, and Sunday
- Estimated price
- €50–260
Flights from Trapani Airport to Luxembourg via Milan Bergamo
- Ave. Duration
- 6h 2m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €100–450
- Website
- luxair.lu
Flights from Catania–Fontanarossa Airport to Luxembourg
- Ave. Duration
- 2h 15m
- When
- Thursday and Sunday
- Estimated price
- €110–470
Flights from Palermo Airport to Luxembourg
- Ave. Duration
- 2h 15m
- When
- Thursday and Sunday
- Estimated price
- €140–600
Flights from Trapani Airport to Luxembourg via Milan Malpensa
- Ave. Duration
- 4h
- When
- Monday and Thursday
- Estimated price
- €100–450
Flights from Trapani Airport to Luxembourg via Bari
- Ave. Duration
- 5h
- When
- Monday
- Estimated price
- €210–900
Flights from Trapani Airport to Luxembourg via Bologna
- Ave. Duration
- 5h 45m
- When
- Friday
- Estimated price
- €100–450
Flights from Trapani Airport to Luxembourg via Rome
- Ave. Duration
- 7h 40m
- When
- Monday, Tuesday, and Friday
- Estimated price
- €200–850
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Luxembourg via Milan Linate
- Ave. Duration
- 4h 32m
- When
- Sunday and Saturday
- Estimated price
- €170–290
Flights from Palermo Airport to Luxembourg via Milan Linate
- Ave. Duration
- 4h 50m
- When
- Monday to Saturday
- Estimated price
- €140–550
Flights from Trapani Airport to Luxembourg via Milan Malpensa
- Ave. Duration
- 4h
- When
- Monday and Thursday
- Estimated price
- €100–450
Flights from Trapani Airport to Luxembourg via Rome
- Ave. Duration
- 7h 40m
- When
- Monday, Tuesday, and Friday
- Estimated price
- €200–850
- Website
- swiss.com
Flights from Catania–Fontanarossa Airport to Luxembourg via Zurich
- Ave. Duration
- 4h 45m
- When
- Thursday and Friday
- Estimated price
- €75–390
Flights from Palermo Airport to Luxembourg via Zurich
- Ave. Duration
- 4h 10m
- When
- Thursday
- Estimated price
- €110–440
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 19m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
Train from Roma Termini to Sestri Levante
- Ave. Duration
- 4h 31m
- Frequency
- Twice daily
- Estimated price
- €45–90
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Sestri Levante to Zuerich Hb
- Ave. Duration
- 7h
- Frequency
- Once daily
- Estimated price
- €65–110
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €80–110
Train from Genova P.Za Principe to Zuerich Hb
- Ave. Duration
- 5h 39m
- Frequency
- Once daily
- Estimated price
- €80–140
- Website
- Trenitalia Eurocity
- 1st Class
- €95–140
- 2nd Class
- €80–110
Train from Zürich HB to Mulhouse
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- €40–65
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Mulhouse
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- €40–65
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Mulhouse Ville to Luxembourg
- Ave. Duration
- 2h 37m
- Frequency
- Twice daily
- Estimated price
- €60–95
- Website
- TGV inOui
Train from Mulhouse Ville to Luxembourg
- Ave. Duration
- 2h 37m
- Frequency
- Twice daily
- Estimated price
- €60–95
- Website
- TGV inOui
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Palermo Piazza Cairoli to Luxembourg Park&Drive
- Ave. Duration
- 33h 46m
- Frequency
- Once a week
- Estimated price
- €290–400
- Website
- Onebus
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Palermo to Aosta
- Ave. Duration
- 26h
- Frequency
- Once daily
- Estimated price
- €160–250
- Website
- Flixbus
Bus from Aosta to Luxembourg, P+R Bouillon
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- €55–85
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Want to know more about travelling around Luxembourg
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Sicily to Luxembourg bus services, operated by Onebus, arrive at Luxembourg Park&Drive station.
Sicily to Luxembourg train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Sicily to Luxembourg train tickets online with Omio.
There are 758+ hotels available in Luxembourg.

























