There are 6 ways to get from Sicily to Mytilene by plane, train, busferry, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Catania–Fontanarossa Airport to Mytilene International Airport Odysseas Elytis
best- Fly from Catania–Fontanarossa Airport (CTA) to Mytilene International Airport Odysseas Elytis (MJT)plane CTA - MJT
5h 54m€64–267Train, bus and ferry, bus, ferry via Ioánnina
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the busferry from Messina - Piazza della Repubblica to Vlorëbusferry
- Take the bus from Vlore , station to Ioanninabus
- Take the bus from Ioannina to Thessaloniki Macedonia KTEL Bus Stationbus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
41h 42mBus and ferry to Malta International Airport, fly to Mytilene International Airport Odysseas Elytis
- Take the busferry from Pozzallo to Vallettabusferry
- Fly from Malta International Airport (MLA) to Mytilene International Airport Odysseas Elytis (MJT)plane MLA - MJT
8h 47m€311–537Fly Catania–Fontanarossa Airport to Chios Airport, ferry
- Fly from Catania–Fontanarossa Airport (CTA) to Chios Airport (JKH)plane CTA - JKH
- Take the ferry from Chios to Mytileneferry
9h 45m€84–330Bus, bus and ferry, ferry
- Take the bus from Palermo to Cosenzabus 582
- Take the busferry from Cosenza - Autostazione to Vlorëbusferry
- Take the bus from Vlore , station to Thessaloniki Macedonia KTEL Bus Stationbus
- Take the bus from Thessaloniki Macedonia KTEL Bus Station to Kavalabus
- Take the ferry from Kavala to Mytileneferry Bsf
45h 49mTrain, bus and ferry, bus, ferry
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the busferry from Messina - Piazza della Repubblica to Tirana, Terminali Lindor I Autobusavebusferry
- Take the bus from Tirana, Terminali Lindor I Autobusave to Thessaloníkibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
2d 5h
Catania–Fontanarossa Airport (CTA) to Mytilene International Airport Odysseas Elytis (MJT) flights
Comparing Your Travel Options
The cheapest way to get from Sicily to Mytilene is to fly which costs €60 - €270 and takes 5h 54m.
The fastest way to get from Sicily to Mytilene is to fly which takes 5h 54m and costs €60 - €270.
The distance between Sicily and Mytilene is 1032 km.
The best way to get from Sicily to Mytilene without a car is to train and bus and ferry and bus and ferry via Ioánnina which takes 41h 42m and costs .
It takes approximately 5h 54m to get from Sicily to Mytilene, including transfers.
Mytilene is 1h ahead of Sicily. It is currently 2:06 AM in Sicily and 3:06 AM in Mytilene.
There are 522+ hotels available in Mytilene.
What companies run services between Sicily, Italy and Mytilene, Greece?
Aegean Airlines and Ryanair fly from Catania–Fontanarossa Airport (CTA) to Mytilene International Airport Odysseas Elytis (MJT) 6 times a week.
- Website
- en.aegeanair.com
Flights from Catania–Fontanarossa Airport to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 4h 5m
- When
- Tuesday, Saturday, and Friday
- Estimated price
- €50–280
Flights from Malta International Airport to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- €50–270
Flights from Malta International Airport to Mytilene International Airport Odysseas Elytis via Thessaloniki
- Ave. Duration
- 3h 40m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €55–250
Flights from Catania–Fontanarossa Airport to Chios Airport via Athens
- Ave. Duration
- 3h 50m
- When
- Saturday, Tuesday, and Friday
- Estimated price
- €55–300
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- 4 times a day
- Estimated price
- €23–45
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- 4 times a day
- Estimated price
- €23–45
- Website
- Trenitalia Intercity
- Phone
- +393293958604
- [email protected]
- Website
- pistoia-viaggi.it
Busferry from Messina - Piazza della Repubblica to Vlorë
- Ave. Duration
- 17h 2m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
Busferry from Cosenza - Autostazione to Vlorë
- Ave. Duration
- 12h 17m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
Busferry from Messina - Piazza della Repubblica to Tirana, Terminali Lindor I Autobusave
- Ave. Duration
- 21h 42m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
- Phone
- +355 69 661 4303
- [email protected]
- Website
- likokostatours.yolasite.com
Bus from Vlore , station to Ioannina
- Ave. Duration
- 3h 6m
- Frequency
- Once daily
- Schedules at
- facebook.com
Bus from Vlore , station to Thessaloniki Macedonia KTEL Bus Station
- Ave. Duration
- 9h 16m
- Frequency
- Once daily
- Schedules at
- facebook.com
- Phone
- +302651083071
- [email protected]
- Website
- KTEL Ioanninon
Bus from Ioannina to Thessaloniki Macedonia KTEL Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 5 times a day
- Estimated price
- €24–35
- Website
- KTEL Ioanninon
- Phone
- (+356) 22069022
- [email protected]
- Website
- Virtu Ferries Ltd
Busferry from Pozzallo to Valletta
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- €73
- Website
- Virtu Ferries Ltd
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Palermo to Cosenza
- Ave. Duration
- 8h 45m
- Frequency
- Once daily
- Estimated price
- €40–65
- Website
- Flixbus
- Phone
- +30 2510.222294
- [email protected]
- Website
- ktelkavalas.gr
Bus from Thessaloniki Macedonia KTEL Bus Station to Kavala
- Ave. Duration
- 2h 10m
- Frequency
- Every 2 hours
- Estimated price
- €12–19
- Schedules at
- ktelkavalas.gr
- Phone
- +355 67 604 2191
- Website
- facebook.com
Bus from Tirana, Terminali Lindor I Autobusave to Thessaloníki
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Schedules at
- autobus.al
- Phone
- +30 21 0891 9800
- [email protected]
- Website
- Blue Star Ferries
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 10h 5m
- Frequency
- Twice a week
- Estimated price
- €70–180
- Website
- Blue Star Ferries
Ferry from Chios to Mytilene
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a week
- Estimated price
- €20–50
- Website
- Blue Star Ferries
Ferry from Kavala to Mytilene
- Ave. Duration
- 7h 55m
- Frequency
- Twice a week
- Estimated price
- €55–140
- Website
- Blue Star Ferries
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 10h 5m
- Frequency
- Twice a week
- Estimated price
- €70–180
- Website
- Blue Star Ferries
- Phone
- +30 210 89 19 800
- [email protected]
- Website
- Hellenic Seaways
Ferry from Chios to Mytilene
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- Hellenic Seaways
- Airplane Type Seats
- €35–50
Want to know more about travelling around Greece
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Getting around the Cyclades
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
































