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How to get fromSicily to Sienaby plane, train, ferry, car, train (Trenitalia), or bus

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There are 10 ways to get from Sicily to Siena by plane, train, ferry, car, train (Trenitalia), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Catania–Fontanarossa Airport to Florence Peretola Airport, train

    best
    1. Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane plane CTA - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    5h 25m
    €47–195

  2. Ferry, drive

    1. Take the ferry from Palermo to Civitavecchiaferry ferry
    2. Drive from Civitavecchia to Sienacar car
    16h 17m
    €74–136

  3. Train (Trenitalia)

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    16h 53m
    €129–290

  4. Bus

    1. Take the bus from Palermo to Sienabus bus N597
    17h 40m
    €91–161

  5. Fly Palermo Airport to Florence Peretola Airport, train

    1. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane plane PMO - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    5h 52m
    €72–207

  6. Fly Catania–Fontanarossa Airport to Pisa International Airport, train

    1. Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane plane CTA - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    5h 18m
    €61–204

  7. Fly Palermo Airport to Pisa International Airport, train

    1. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane plane PMO - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    5h 40m
    €56–256

  8. Fly Trapani Airport to Pisa International Airport, train

    1. Fly from Trapani Airport (TPS) to Pisa International Airport (PSA)plane plane TPS - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    5h 21m
    €55–323

  9. Train via Chiusi (Trenitalia)

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Chiusi-Chianciano T.train train
    3. Take the train from Chiusi-Chianciano T. to Sienatrain train Re
    17h 47m
    €117–244

  10. Bus via Florence

    1. Take the bus from Palermo Piazza Cairoli to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    23h 8m

Sicily to Siena by train (Trenitalia)

Calendar14Weekly Trains
Duration16h 53mAverage Duration
Ticket€129Cheapest Price
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Questions & Answers

Map of how to get from Sicily to Siena.ExpandLaunch map view
  • Distance: 875 km
  • Duration: 5h 25m

What companies run services between Sicily, Italy and Siena, Italy?

You can take a train from Palermo Notarbartolo to Siena via Palermo Centrale, Roma Termini, and Firenze S.M.N. in around 16h 53m. Alternatively, FlixBus operates a bus from Palermo to Siena once daily. Tickets cost €90–160 and the journey takes 16h 20m.

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