There are 10 ways to get from Siena to Agrigento by train, plane, car, car ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly to Palermo Airport, train
best- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
7h 54m€90–235Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus
cheapest- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
8h 12m€53–221Drive, car ferry
- Drive from Siena to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
- Drive from Palermo Porto to Agrigentocar
17h 53m€108–161Bus
- Take the bus from Siena to Agrigentobus N528
18h 45m€90–150Train (Trenitalia)
- Take the train from Siena to Chiusi-Chianciano T.train Re
- Take the train from Chiusi-Chianciano T. to Roma Terminitrain Re
- Take the train from Roma Termini to Palermo Centraletrain Ic
- Take the train from Palermo Centrale to Agrigento Centraletrain Re
19h 25m€138–279Train, train to Pisa International Airport, fly to Palermo Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
7h 57m€74–294Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
8h 20m€64–240Train, train to Pisa International Airport, fly to Trapani Airport, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)plane PSA - TPS
- Take the bus from Trapani Birgi Airport to Agrigento - piazz.le Fratelli Rossellibus
8h 30m€62–272Bus to Perugia Sant'Egidio Airport, fly to Palermo Airport, train
- Take the bus from Siena to Perugiabus
- Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane PEG - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
8h 59m€81–282Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the bus from Florence Villa Constanza Bus Station to Agrigento Piazzale Rossellibus
23h 11m€207–288
Siena to Agrigento by bus
Questions & Answers
The cheapest way to get from Siena to Agrigento is to bus which costs €90 - €150 and takes 18h 45m.
The fastest way to get from Siena to Agrigento is to train and fly which takes 7h 54m and costs €85 - €240.
Yes, there is a direct bus departing from Siena and arriving at Agrigento. Services depart once daily, and operate every day. The journey takes approximately 18h 45m.
No, there is no direct train from Siena to Agrigento. However, there are services departing from Siena and arriving at Agrigento Centrale via Chiusi-Chianciano T., Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 19h 25m.
The distance between Siena and Agrigento is 912 km.
The best way to get from Siena to Agrigento without a car is to bus which takes 18h 45m and costs €90 - €150.
It takes approximately 7h 54m to get from Siena to Agrigento, including transfers.
Siena to Agrigento bus services, operated by FlixBus, depart from Siena station.
Siena to Agrigento train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Agrigento is to bus which takes 18h 45m and costs €90 - €150. Alternatively, you can train, which costs €130 - €280 and takes 19h 25m.
What companies run services between Siena, Italy and Agrigento, Italy?
FlixBus operates a bus from Siena to Agrigento once daily. Tickets cost €90–150 and the journey takes 18h 45m. Alternatively, you can take a train from Siena to Agrigento Centrale via Chiusi-Chianciano T., Roma Termini, and Palermo Centrale in around 19h 25m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–210
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €30–180
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Monday
- Estimated price
- €30–180
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €30–180
Flights from Pisa International Airport to Trapani Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €35–220
Flights from Perugia Sant'Egidio Airport to Palermo Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €50–220
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Palermo Aeroporto to Agrigento Centrale
- Ave. Duration
- 2h 32m
- Frequency
- 4 times a day
- Estimated price
- €21–35
- Website
- Trenitalia
Train from Siena to Chiusi-Chianciano T.
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- €11–18
- Website
- Trenitalia
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 5m
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia
Train from Palermo Centrale to Agrigento Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €16–27
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- Trenitalia
Train from Palermo Aeroporto to Agrigento Centrale
- Ave. Duration
- 2h 32m
- Frequency
- 4 times a day
- Estimated price
- €21–35
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- Trenitalia
Train from Palermo Aeroporto to Agrigento Centrale
- Ave. Duration
- 2h 32m
- Frequency
- 4 times a day
- Estimated price
- €21–35
- Website
- Trenitalia
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Siena to Agrigento
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €90–150
- Website
- Flixbus
Bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rosselli
- Ave. Duration
- 2h 19m
- Frequency
- Twice daily
- Estimated price
- €12–21
- Website
- Flixbus
Bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rosselli
- Ave. Duration
- 2h 19m
- Frequency
- Twice daily
- Estimated price
- €12–21
- Website
- Flixbus
Bus from Siena to Perugia
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €8–13
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €60–90
- Website
- Grandi Navi Veloci
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More Questions & Answers
Siena to Agrigento bus services, operated by FlixBus, arrive at Agrigento station.
Siena to Agrigento train services, operated by Trenitalia, arrive at Chiusi-Chianciano T. station.
Book your Siena to Agrigento train tickets online with Omio.
Book your Siena to Agrigento bus tickets online with Omio and FlixBus.
There are 1300+ hotels available in Agrigento.











