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How to get fromSiena to Brindisiby train (Trenitalia), bus, car, train, or plane

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There are 10 ways to get from Siena to Brindisi by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Rome (Trenitalia)

    best
    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    3. Take the train from Roma Termini to Brindisitrain train Fr / ...
    9h 42m
    €125–278

  2. Bus

    cheapest
    1. Take the bus from Siena Central Train Station to Brindisi Istituto Professionale Falconebus bus Itabus
    10h 40m
    €50–120

  3. Drive 745.4 km

    1. Drive from Siena to Brindisicar car 745.4 km
    7h 48m
    €117–168

  4. Train to Florence Peretola Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Brindisi Airport (BDS)plane plane FLR - BDS
    5h 52m
    €94–240

  5. Train (Trenitalia)

    1. Take the train from Siena to Firenze S.M.N.train train Re / ...
    2. Take the train from Firenze S.M.N. to Brindisitrain train Fr
    9h 48m
    €132–268

  6. Bus via Termoli

    1. Take the bus from Siena to Termolibus bus 443
    2. Take the bus from Termoli to Brindisibus bus N425
    13h 35m
    €60–96

  7. Train, train to Pisa International Airport, fly

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Brindisi Airport (BDS)plane plane PSA - BDS
    4h 35m
    €58–259

  8. Train, train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Brindisi Airport (BDS)plane plane BLQ - BDS
    4h 55m
    €62–288

  9. Train, train to Fiumicino International Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    3. Fly from Fiumicino International Airport (FCO) to Brindisi Airport (BDS)plane plane FCO - BDS
    6h 4m
    €74–285

  10. Bus to Perugia Sant'Egidio Airport, fly

    1. Take the bus from Siena to Perugiabus bus
    2. Fly from Perugia Sant'Egidio Airport (PEG) to Brindisi Airport (BDS)plane plane PEG - BDS
    5h 22m
    €60–267

Siena to Brindisi by train (Trenitalia)

Calendar79Weekly Trains
Duration9h 42mAverage Duration
Ticket€125Cheapest Price
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Questions & Answers

Map of how to get from Siena to Brindisi.ExpandLaunch map view
  • Distance: 942.3 km
  • Duration: 9h 42m

What companies run services between Siena, Italy and Brindisi, Italy?

You can take a train from Siena to Brindisi via Firenze S.M.N. and Roma Termini in around 9h 42m. Alternatively, Itabus S.p.A. operates a bus from Siena Central Train Station to Brindisi Istituto Professionale Falcone once daily. Tickets cost €50–120 and the journey takes 10h 40m.

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