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How to get fromSiena to Brindisiby train, plane, train (Trenitalia), bus, or car

Find Transport to Brindisi

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There are 9 ways to get from Siena to Brindisi by train, plane, train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Brindisi Airport (BDS)plane plane FLR - BDS
    5h 52m
    €94–250

  2. Bus

    cheapest
    1. Take the bus from Siena Central Train Station to Brindisi Istituto Professionale Falconebus bus Itabus
    10h 40m
    €45–100

  3. Train (Trenitalia)

    1. Take the train from Siena to Firenze S.M.N.train train Re / ...
    2. Take the train from Firenze S.M.N. to Brindisitrain train Fr
    9h 48m
    €132–258

  4. Drive  745.4 km

    1. Drive from Siena to Brindisicar car 745.4 km
    7h 48m
    €118–170

  5. Train, train to Pisa International Airport, fly

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Brindisi Airport (BDS)plane plane PSA - BDS
    4h 42m
    €63–258

  6. Train, train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Brindisi Airport (BDS)plane plane BLQ - BDS
    5h 2m
    €62–298

  7. Train, train to Fiumicino International Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    3. Fly from Fiumicino International Airport (FCO) to Brindisi Airport (BDS)plane plane FCO - BDS
    6h 17m
    €73–280

  8. Bus to Perugia Sant'Egidio Airport, fly

    1. Take the bus from Siena to Perugiabus bus
    2. Fly from Perugia Sant'Egidio Airport (PEG) to Brindisi Airport (BDS)plane plane PEG - BDS
    5h 22m
    €61–297

  9. Bus via Termoli

    1. Take the bus from Siena to Termolibus bus 443
    2. Take the bus from Termoli to Brindisibus bus N425
    13h 35m
    €63–104

Siena to Brindisi by train (Trenitalia)

Calendar7Weekly Trains
Duration9h 48mAverage Duration
Ticket€132Cheapest Price
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Questions & Answers

Map of how to get from Siena to Brindisi.ExpandLaunch map view
  • Distance: 753.5 km
  • Duration: 5h 52m

What companies run services between Siena, Italy and Brindisi, Italy?

You can take a train from Siena to Brindisi via Firenze S.M.N. in around 9h 48m. Alternatively, Itabus S.p.A. operates a bus from Siena Central Train Station to Brindisi Istituto Professionale Falcone once daily. Tickets cost €45–100 and the journey takes 10h 40m.

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