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How to get fromSiena to Caltanissettaby train, plane, bus, car, car ferry, or train (Trenitalia)

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There are 9 ways to get from Siena to Caltanissetta by train, plane, bus, car, car ferry, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane plane FLR - CTA
    3. Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus bus
    6h 57m
    €50–211
  2. Drive, car ferry

    1. Drive from Siena to Civitavecchia Portcar car
    2. Take the carferry from Civitavecchia Port to Palermo Portocarferry car ferry
    3. Drive from Palermo Porto to Caltanissettacar car
    17h 22m
    €109–161
  3. Bus

    1. Take the bus from Siena to Caltanissettabus bus N528
    17h 55m
    €85–140
  4. Train (Trenitalia)

    1. Take the train from Siena to Chiusi-Chianciano T.train train Re
    2. Take the train from Chiusi-Chianciano T. to Roma Terminitrain train Re
    3. Take the train from Roma Termini to Termini Imeresetrain train Ic
    4. Take the train from Termini Imerese to Caltanissetta Xirbitrain train Re
    18h 47m
    €129–262
  5. Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane plane PSA - CTA
    4. Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus bus
    7h 5m
    €61–230
  6. Train, train to Pisa International Airport, fly to Palermo Airport

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane plane PSA - PMO
    4. Take the train from Palermo Centrale to Caltanissetta Xirbitrain train
    8h 45m
    €73–284
  7. Train, train to Pisa International Airport, fly to Vincenzo Magliocco Airport

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Vincenzo Magliocco Airport (CIY)plane plane PSA - CIY
    4. Take the train from Comiso to Caltanissetta C.Letrain train
    8h
    €129–425
  8. Bus to Perugia Sant'Egidio Airport, fly to Catania–Fontanarossa Airport, bus

    1. Take the bus from Siena to Perugiabus bus
    2. Fly from Perugia Sant'Egidio Airport (PEG) to Catania–Fontanarossa Airport (CTA)plane plane PEG - CTA
    3. Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus bus
    8h 2m
    €63–278
  9. Bus via Florence

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131R / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Caltanissettabus bus
    19h 50m
    €177–248

Siena to Caltanissetta by bus

Calendar7Weekly Buses
Duration17h 55mAverage Duration
Ticket€85Cheapest Price
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Questions & Answers

What companies run services between Siena, Italy and Caltanissetta, Italy?

FlixBus operates a bus from Siena to Caltanissetta once daily. Tickets cost €85–140 and the journey takes 17h 55m. Alternatively, you can take a train from Siena to Caltanissetta C.Le via Chiusi-Chianciano T., Roma Termini, Termini Imerese, and Caltanissetta Xirbi in around 18h 47m.

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