There are 9 ways to get from Siena to Caltanissetta by train, plane, bus, car, car ferry, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus
best- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
6h 57m€47–208Drive, car ferry
- Drive from Siena to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
- Drive from Palermo Porto to Caltanissettacar
17h 22m€109–157Train via Catania (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Catania Centraletrain Ic
- Take the train from Catania Centrale to Caltanissetta Xirbitrain Re
17h 23m€127–250Bus
- Take the bus from Siena to Caltanissettabus N528
17h 55m€90–140Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
7h 5m€60–236Train, train to Pisa International Airport, fly to Palermo Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
- Take the train from Palermo Centrale to Caltanissetta Xirbitrain
8h 43m€72–274Bus to Perugia Sant'Egidio Airport, fly to Catania–Fontanarossa Airport, bus
- Take the bus from Siena to Perugiabus
- Fly from Perugia Sant'Egidio Airport (PEG) to Catania–Fontanarossa Airport (CTA)plane PEG - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
8h 2m€64–288Train (Trenitalia)
- Take the train from Siena to Chiusi-Chianciano T.train Re
- Take the train from Chiusi-Chianciano T. to Roma Terminitrain Re
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Caltanissetta Xirbitrain Re
18h 41m€122–219Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the bus from Florence Villa Constanza Bus Station to Caltanissettabus
19h 50m€177–248
Siena to Caltanissetta by train (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Siena to Caltanissetta is to train and fly and bus which costs €45 - €210 and takes 6h 57m.
The fastest way to get from Siena to Caltanissetta is to train and fly and bus which takes 6h 57m and costs €45 - €210.
Yes, there is a direct bus departing from Siena and arriving at Caltanissetta. Services depart once daily, and operate every day. The journey takes approximately 17h 55m.
No, there is no direct train from Siena to Caltanissetta. However, there are services departing from Siena and arriving at Caltanissetta C.Le via Firenze S.M.N., Roma Termini, Catania Centrale and Caltanissetta Xirbi. The journey, including transfers, takes approximately 17h 23m.
The distance between Siena and Caltanissetta is 982 km.
The best way to get from Siena to Caltanissetta without a car is to train via Catania which takes 17h 23m and costs €120 - €250.
It takes approximately 6h 57m to get from Siena to Caltanissetta, including transfers.
Siena to Caltanissetta bus services, operated by FlixBus, depart from Siena station.
Siena to Caltanissetta train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Caltanissetta is to train via Catania which takes 17h 23m and costs €120 - €250. Alternatively, you can bus, which costs €90 - €140 and takes 17h 55m.
What companies run services between Siena, Italy and Caltanissetta, Italy?
You can take a train from Siena to Caltanissetta C.Le via Firenze S.M.N., Roma Termini, Catania Centrale, and Caltanissetta Xirbi in around 17h 23m. Alternatively, FlixBus operates a bus from Siena to Caltanissetta once daily. Tickets cost €90–140 and the journey takes 17h 55m.
- Website
- ryanair.com
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €30–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 25m
- When
- Thursday
- Estimated price
- €30–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €30–190
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–200
Flights from Perugia Sant'Egidio Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €45–220
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Catania Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Palermo Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 29m
- Frequency
- Every 2 hours
- Estimated price
- €15–21
- Website
- Trenitalia
Train from Siena to Chiusi-Chianciano T.
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €17–25
- Website
- Trenitalia
Train from Termini Imerese to Caltanissetta Xirbi
- Ave. Duration
- 1h 4m
- Frequency
- Every 2 hours
- Estimated price
- €10–15
- Website
- Trenitalia
- Phone
- +39 0912742800
- [email protected]
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €60–85
- Website
- Grandi Navi Veloci
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Booking & Getting There
Siena to Caltanissetta bus services, operated by FlixBus, arrive at Caltanissetta station.
Siena to Caltanissetta train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Siena to Caltanissetta train tickets online with Omio.
Book your Siena to Caltanissetta bus tickets online with Omio and FlixBus.
There are 243+ hotels available in Caltanissetta.









