There are 12 ways to get from Siena to Caltanissetta by train, plane, bus, car, car ferry, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus
best- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
6h 57m€44–208Drive, car ferry
- Drive from Siena to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
- Drive from Palermo Porto to Caltanissettacar
17h 22m€111–163Bus
- Take the bus from Siena to Caltanissettabus N528
17h 55m€95–150Train (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Caltanissetta Xirbitrain Re
17h 56m€135–266Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
7h 5m€61–236Train to Florence Peretola Airport, fly to Palermo Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
- Take the train from Palermo Centrale to Caltanissetta Xirbitrain
8h 41m€93–256Train, train to Bologna Guglielmo Marconi Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Catania–Fontanarossa Airport (CTA)plane BLQ - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
7h 36m€46–276Train, train to Pisa International Airport, fly to Palermo Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
- Take the train from Palermo Centrale to Caltanissetta Xirbitrain
8h 44m€73–284Bus to Perugia Sant'Egidio Airport, fly to Catania–Fontanarossa Airport, bus
- Take the bus from Siena to Perugiabus
- Fly from Perugia Sant'Egidio Airport (PEG) to Catania–Fontanarossa Airport (CTA)plane PEG - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
8h 2m€64–288Train, train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane FCO - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
8h 35m€72–207Train via Chiusi (Trenitalia)
- Take the train from Siena to Chiusi-Chianciano T.train Re
- Take the train from Chiusi-Chianciano T. to Roma Terminitrain Re
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Caltanissetta Xirbitrain Re
18h 41m€123–230Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the bus from Florence Villa Constanza Bus Station to Caltanissettabus
19h 50m€177–248
Siena to Caltanissetta by bus
Comparing Your Travel Options
The cheapest way to get from Siena to Caltanissetta is to train and fly and bus which costs €45 - €280 and takes 7h 36m.
The fastest way to get from Siena to Caltanissetta is to train and fly and bus which takes 6h 57m and costs €40 - €210.
Yes, there is a direct bus departing from Siena and arriving at Caltanissetta. Services depart once daily, and operate every day. The journey takes approximately 17h 55m.
No, there is no direct train from Siena to Caltanissetta. However, there are services departing from Siena and arriving at Caltanissetta C.Le via Firenze S.M.N., Roma Termini, Termini Imerese and Caltanissetta Xirbi. The journey, including transfers, takes approximately 17h 56m.
The distance between Siena and Caltanissetta is 982 km.
The best way to get from Siena to Caltanissetta without a car is to bus which takes 17h 55m and costs €95 - €150.
It takes approximately 6h 57m to get from Siena to Caltanissetta, including transfers.
Siena to Caltanissetta bus services, operated by FlixBus, depart from Siena station.
Siena to Caltanissetta train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Caltanissetta is to bus which takes 17h 55m and costs €95 - €150. Alternatively, you can train, which costs €130 - €270 and takes 17h 56m.
What companies run services between Siena, Italy and Caltanissetta, Italy?
FlixBus operates a bus from Siena to Caltanissetta once daily. Tickets cost €95–150 and the journey takes 17h 55m. Alternatively, you can take a train from Siena to Caltanissetta C.Le via Firenze S.M.N., Roma Termini, Termini Imerese, and Caltanissetta Xirbi in around 17h 56m.
- Website
- ryanair.com
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €30–180
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 25m
- When
- Thursday
- Estimated price
- €30–180
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €30–180
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–210
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 47m
- When
- Tuesday and Thursday
- Estimated price
- €30–210
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 3h 35m
- When
- Wednesday and Saturday
- Estimated price
- €30–210
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–210
Flights from Perugia Sant'Egidio Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €45–230
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €22–75
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 20m
- When
- Monday
- Estimated price
- €22–75
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Fiumicino International Airport
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–180
Flights from Florence Peretola Airport to Palermo Airport via Fiumicino International Airport
- Ave. Duration
- 3h 14m
- When
- Every day
- Estimated price
- €85–180
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Fiumicino International Airport
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- €85–200
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €45–120
- Website
- volotea.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €16–110
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Fiumicino International Airport
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–180
Flights from Florence Peretola Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €20–140
Flights from Florence Peretola Airport to Palermo Airport via Fiumicino International Airport
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–180
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Fiumicino International Airport
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- €85–200
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €45–120
- Website
- flyulendo.com
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €15–90
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €21–70
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €22–110
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €21–110
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €35–200
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Termini Imerese to Caltanissetta Xirbi
- Ave. Duration
- 1h 4m
- Frequency
- Every 2 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Palermo Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 29m
- Frequency
- Every 2 hours
- Estimated price
- €15–21
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Palermo Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 29m
- Frequency
- Every 2 hours
- Estimated price
- €15–21
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Siena to Chiusi-Chianciano T.
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €18–25
- Website
- Trenitalia
Train from Termini Imerese to Caltanissetta Xirbi
- Ave. Duration
- 1h 4m
- Frequency
- Every 2 hours
- Estimated price
- €10–15
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 10h 57m
- Frequency
- 4 times a day
- Estimated price
- €85–170
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- €16–29
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 10h 57m
- Frequency
- 4 times a day
- Estimated price
- €85–170
- Website
- Trenitalia Intercity
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 39 min
- Frequency
- 4 times a day
- Estimated price
- €10–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 0912742800
- [email protected]
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Siena to Caltanissetta
- Ave. Duration
- 17h 55m
- Frequency
- Once daily
- Estimated price
- €95–150
- Website
- Flixbus
Bus from Siena to Perugia
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €9–14
- Website
- Flixbus
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Schedules at
- at-bus.it
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Florence Villa Constanza Bus Station to Caltanissetta
- Ave. Duration
- 17h 11m
- Frequency
- Twice a week
- Estimated price
- €170–240
- Website
- Onebus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €60–85
- Website
- Grandi Navi Veloci
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Booking & Getting There
Siena to Caltanissetta bus services, operated by FlixBus, arrive at Caltanissetta station.
Siena to Caltanissetta train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Siena to Caltanissetta train tickets online with Omio.
Book your Siena to Caltanissetta bus tickets online with Omio and FlixBus.
There are 249+ hotels available in Caltanissetta.




































