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How to get fromSiena to Frankfurt am Mainby train, plane, bus, train (Trenitalia), or car

Find Transport to Frankfurt am Main

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There are 9 ways to get from Siena to Frankfurt am Main by train, plane, bus, train (Trenitalia), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane plane FLR - FRA
    6h 2m
    €127–287

  2. Bus

    cheapest
    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 1509 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Frankfurt central train stationbus bus N77 / ...
    19h 20m
    €91–160

  3. Bus via Mühlheim am Main

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 1509 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Mühlheim am Mainbus bus
    11h 34m

  4. Train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Frankfurt(Main)Hbftrain train Ec
    12h 21m
    €172–309

  5. Drive 1,024.6 km

    1. Drive from Siena to Frankfurt am Maincar car 1,024.6 km
    9h 53m
    €159–230

  6. Train, train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)plane plane BLQ - FRA
    6h 30m
    €119–325

  7. Train, train to Pisa International Airport, fly

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Frankfurt (FRA)plane plane PSA - FRA
    6h 10m
    €121–266

  8. Train, train to Venice Marco Polo Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Venezia Mestretrain train
    3. Fly from Venice Marco Polo Airport (VCE) to Frankfurt (FRA)plane plane VCE - FRA
    8h 16m
    €116–287

  9. Train via Basel

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    4. Take the train from Basel SBB to Frankfurttrain train 12 / ...
    12h 43m
    €177–599

Siena to Frankfurt am Main by train

Calendar16Weekly Trains
Duration12h 21mAverage Duration
Ticket€172Cheapest Price
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Questions & Answers

Map of how to get from Siena to Frankfurt am Main.ExpandLaunch map view
  • Distance: 834 km
  • Duration: 6h 2m

What companies run services between Siena, Italy and Frankfurt am Main, Germany?

You can take a bus from Siena to Frankfurt Konstablerwache via Florence Villa Constanza Bus Station, Mühlheim am Main, Mühlheim, Offenbach, and Offenbach in around 11h 34m. Alternatively, you can take a train from Siena to Frankfurt(Main)Hbf via Firenze S.M.N. and Milano Centrale in around 12h 21m.

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