There are 8 ways to get from Siena to Grenoble by train (Trenitalia, TGV), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Chambery Challes Les Eauxtrain Tgv
- Take the train from Chambery Challes Les Eaux to Grenobletrain Ter
9h 32m€112–249Bus
cheapest- Take the bus from Siena to Florence Villa Constanza Bus Stationbus 1509 / ...
- Take the bus from Florence Villa Constanza Bus Station to Grenoblebus 1501
10h 50m€50–88Drive 661 km
- Drive from Siena to Grenoblecar 661 km
7h 22m€103–149Train, train to Bologna Guglielmo Marconi Airport, fly to Lyon–Saint Exupéry Airport
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Lyon–Saint Exupéry Airport (LYS)plane BLQ - LYS
- Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
7h 59m€110–349Bus via Turin
- Take the bus from Siena Central Train Station to Turin Corso Vittorio Emanuele IIbus Itabus
- Take the bus from Turin to Grenoblebus FlixBus N740 / ...
13h 35m€51–116Train to Florence Peretola Airport, fly to Lyon–Saint Exupéry Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Lyon–Saint Exupéry Airport (LYS)plane FLR - LYS
- Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
7h 16m€102–291Train, train to Fiumicino International Airport, fly to Lyon–Saint Exupéry Airport
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Lyon–Saint Exupéry Airport (LYS)plane FCO - LYS
- Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
9h 28m€122–356Train, train to Fiumicino International Airport, fly to Geneva International Airport, bus
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Geneva International Airport (GVA)plane FCO - GVA
- Take the bus from Geneva - Airport Bus Station to Chambéry - Bus Stationbus
- Take the train from Chambery Challes Les Eaux to Grenobletrain
10h 38m€117–355
Siena to Grenoble by train
Questions & Answers
The cheapest way to get from Siena to Grenoble is to bus which costs €50 - €90 and takes 10h 50m.
The fastest way to get from Siena to Grenoble is to train and fly which takes 7h 16m and costs €100 - €300.
No, there is no direct bus from Siena to Grenoble. However, there are services departing from Siena and arriving at Grenoble via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 10h 50m.
No, there is no direct train from Siena to Grenoble. However, there are services departing from Siena and arriving at Grenoble via Firenze S.M.N., Torino Porta Susa and Chambery Challes Les Eaux. The journey, including transfers, takes approximately 9h 32m.
The distance between Siena and Grenoble is 803 km. The road distance is 661 km.
The best way to get from Siena to Grenoble without a car is to train which takes 9h 32m and costs €110 - €250.
It takes approximately 9h 32m to get from Siena to Grenoble, including transfers.
Siena to Grenoble bus services, operated by FlixBus, depart from Siena station.
Siena to Grenoble train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Grenoble is to train which takes 9h 32m and costs €110 - €250. Alternatively, you can bus, which costs €50 - €90 and takes 10h 50m.
What companies run services between Siena, Italy and Grenoble, France?
You can take a train from Siena to Grenoble via Firenze S.M.N., Torino Porta Susa, and Chambery Challes Les Eaux in around 9h 32m. Alternatively, you can take a bus from Siena to Grenoble via Florence Villa Constanza Bus Station in around 10h 50m.
- Website
- easyjet.com
Flights from Fiumicino International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 38m
- When
- Monday, Wednesday, Sunday, Tuesday, Thursday, and Friday
- Estimated price
- €45–200
Flights from Fiumicino International Airport to Geneva International Airport
- Ave. Duration
- 1h 31m
- When
- Friday, Sunday, Wednesday, Monday, Tuesday, and Thursday
- Estimated price
- €45–190
Flights from Fiumicino International Airport to Geneva International Airport via Nice
- Ave. Duration
- 3h 32m
- When
- Thursday, Monday, Wednesday, Friday, and Sunday
- Estimated price
- €45–190
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Geneva International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- €70–190
- Website
- twinjet.fr
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €600–900
- Website
- lufthansa.com
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 3h 35m
- When
- Monday to Saturday
- Estimated price
- €110–270
- Website
- volotea.com
Flights from Florence Peretola Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday and Friday
- Estimated price
- €30–200
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Torino Porta Susa to Chambery Challes Les Eaux
- Ave. Duration
- 2h 35m
- Frequency
- 4 times a day
- Estimated price
- €24–40
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Torino Porta Susa
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €65–130
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 15 minutes
- Estimated price
- €35–80
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 15 minutes
- Estimated price
- €35–80
- Schedules at
- Trenitalia Frecce
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Torino Porta Susa to Chambery Challes Les Eaux
- Ave. Duration
- 2h 36m
- Frequency
- Every 4 hours
- Estimated price
- €35–65
- Website
- TGV inOui
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- TGV inOui
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- TGV inOui
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 48 min
- Frequency
- Every 20 minutes
- Estimated price
- €11–22
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 48 min
- Frequency
- Every 20 minutes
- Estimated price
- €11–22
- Website
- Oui.SNCF
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €17–35
- Website
- Zou! Lignes Express Régionales
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €17–35
- Website
- Zou! Lignes Express Régionales
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- 4 times a day
- Estimated price
- €12–23
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Twice daily
- Estimated price
- €10–21
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €4–8
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Grenoble
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- €45–80
- Website
- Flixbus
Bus from Turin to Grenoble
- Ave. Duration
- 3h 40m
- Frequency
- Every 4 hours
- Estimated price
- €17–29
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Siena Central Train Station to Turin Corso Vittorio Emanuele II
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- €35–80
- Website
- Itabus S.p.A.
Bus from Turin to Grenoble
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- €15–35
- Website
- Itabus S.p.A.
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Turin to Grenoble
- Ave. Duration
- 3h 25m
- Frequency
- 4 times a day
- Estimated price
- €20–40
- Website
- BlaBlaCar Bus
Bus from Geneva - Airport Bus Station to Chambéry - Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–14
- Website
- BlaBlaCar Bus
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Italy Travel Guides
Read the travel guide
More Questions & Answers
Siena to Grenoble bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Siena to Grenoble train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Grenoble is 661 km. It takes approximately 7h 22m to drive from Siena to Grenoble.
Book your Siena to Grenoble train tickets online with Omio.
Book your Siena to Grenoble bus tickets online with Omio and FlixBus.
There are 2294+ hotels available in Grenoble.










































