There are 11 ways to get from Siena to Karlsruhe by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
11h 9m€151–260Bus via Karlsruhe central train station
cheapest- Take the bus from Siena to Florence Villa Constanza Bus Stationbus 1509 / ...
- Take the bus from Florence Villa Constanza Bus Station to Karlsruhe central train stationbus N77
17h€86–129Bus
- Take the bus from Siena to Florence Villa Constanza Bus Stationbus 1509 / ...
- Take the bus from Florence Villa Constanza Bus Station to Karlsruhe Central Bus Stationbus
13h 5m€116–169Drive 890.1 km
- Drive from Siena to Karlsruhecar 890.1 km
8h 47m€144–208Train to Florence Peretola Airport, fly to Stuttgart Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Stuttgart Airport (STR)plane FLR - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
8h 32m€140–397Train via Basel
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Basel Sbbtrain Ec
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain 12 / ...
11h 23m€146–295Train to Florence Peretola Airport, fly to Frankfurt, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane FLR - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
7h 40m€147–367Train, train to Bologna Guglielmo Marconi Airport, fly to Frankfurt
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)plane BLQ - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
8h 9m€129–395Train to Florence Peretola Airport, fly to Zurich Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Zurich Airport (ZRH)plane FLR - ZRH
- Take the train from Zürich HB to Basel SBBtrain
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
9h 3m€171–456Train to Florence Peretola Airport, fly to Munich International Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Munich International Airport (MUC)plane FLR - MUC
- Take the train from Flughafen München to Pasingtrain
- Take the train from Pasing to Karlsruhe Hauptbahnhoftrain
9h 56m€181–452Train to Florence Peretola Airport, fly to Strasbourg International Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Strasbourg International Airport (SXB)plane FLR - SXB
- Take the train from Strasbourg to Karlsruhe Hbftrain
7h 16m€87–360
Siena to Karlsruhe by train
Comparing Your Travel Options
The cheapest way to get from Siena to Karlsruhe is to bus via Karlsruhe central train station which costs €85 - €130 and takes 17h.
The fastest way to get from Siena to Karlsruhe is to train and fly which takes 7h 16m and costs €85 - €360.
No, there is no direct bus from Siena to Karlsruhe station. However, there are services departing from Siena and arriving at Karlsruhe Central Bus Station via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 13h 5m.
No, there is no direct train from Siena to Karlsruhe. However, there are services departing from Siena and arriving at Karlsruhe Hbf via Firenze S.M.N. and Milano Centrale. The journey, including transfers, takes approximately 11h 9m.
The distance between Siena and Karlsruhe is 928 km. The road distance is 890.1 km.
The best way to get from Siena to Karlsruhe without a car is to train which takes 11h 9m and costs €150 - €260.
It takes approximately 11h 9m to get from Siena to Karlsruhe, including transfers.
Siena to Karlsruhe bus services, operated by FlixBus, depart from Siena station.
Siena to Karlsruhe train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Karlsruhe is to train which takes 11h 9m and costs €150 - €260. Alternatively, you can bus, which costs €110 - €170 and takes 13h 5m.
What companies run services between Siena, Italy and Karlsruhe, Germany?
You can take a train from Siena to Karlsruhe Hbf via Firenze S.M.N. and Milano Centrale in around 11h 9m. Alternatively, you can take a bus from Siena to Karlsruhe Central Bus Station via Florence Villa Constanza Bus Station in around 13h 5m.
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Stuttgart Airport via Munich International Airport
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €190–600
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–470
Flights from Florence Peretola Airport to Frankfurt via Munich International Airport
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €150–490
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €130–420
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Munich International Airport
- Ave. Duration
- 3h 38m
- When
- Monday to Saturday
- Estimated price
- €130–430
Flights from Florence Peretola Airport to Zurich Airport via Munich International Airport
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €160–550
Flights from Florence Peretola Airport to Zurich Airport via Frankfurt
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €170–600
Flights from Florence Peretola Airport to Munich International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €170–550
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Stuttgart Airport via Rome
- Ave. Duration
- 4h 40m
- When
- Saturday, Sunday, Monday, Wednesday, and Friday
- Estimated price
- €140–310
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–470
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €130–420
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Munich International Airport
- Ave. Duration
- 3h 55m
- When
- Monday to Saturday
- Estimated price
- €130–430
Flights from Florence Peretola Airport to Zurich Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- €85–360
Flights from Florence Peretola Airport to Munich International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €170–550
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €150–470
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €130–420
Flights from Florence Peretola Airport to Zurich Airport via Munich International Airport
- Ave. Duration
- 3h 20m
- When
- Saturday
- Estimated price
- €160–550
Flights from Florence Peretola Airport to Zurich Airport via Frankfurt
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €170–600
Flights from Florence Peretola Airport to Munich International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €170–550
- Website
- swiss.com
Flights from Florence Peretola Airport to Stuttgart Airport via Zurich Airport
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €100–180
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Zurich Airport
- Ave. Duration
- 3h 25m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- €70–280
Flights from Florence Peretola Airport to Zurich Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- €85–360
Flights from Florence Peretola Airport to Munich International Airport via Zurich Airport
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €90–370
- Website
- austrian.com
Flights from Florence Peretola Airport to Stuttgart Airport via Vienna
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €100–430
Flights from Florence Peretola Airport to Munich International Airport via Vienna
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €90–390
- Website
- condor.com
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–320
- Website
- volotea.com
Flights from Florence Peretola Airport to Strasbourg International Airport
- Ave. Duration
- 1h 25m
- When
- Wednesday and Sunday
- Estimated price
- €40–290
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 39 min
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Karlsruhe Hbf
- Ave. Duration
- 6h 19m
- Frequency
- Once daily
- Estimated price
- €110–170
- Website
- Trenitalia Eurocity
- 1st Class
- €110–170
- 2nd Class
- €110–150
Train from Milano Centrale to Basel Sbb
- Ave. Duration
- 4h 20m
- Frequency
- Every 3 hours
- Estimated price
- €75–130
- Website
- Trenitalia Eurocity
- 1st Class
- €90–130
- 2nd Class
- €75–110
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €14–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €23–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €23–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Pasing to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 43m
- Frequency
- Every 4 hours
- Estimated price
- €50–120
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 41 min
- Frequency
- Every 4 hours
- Estimated price
- €13–30
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €15–65
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Flughafen München to Pasing
- Ave. Duration
- 49 min
- Frequency
- Every 20 minutes
- Estimated price
- €8–35
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Twice daily
- Estimated price
- €14–28
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Twice daily
- Estimated price
- €14–28
- Website
- Nederlandse Spoorwegen (NS)
Train from Zürich HB to Basel SBB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €30–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- €16–24
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 49 min
- Frequency
- Twice a week
- Estimated price
- €14–23
- Website
- Oui.SNCF
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Karlsruhe central train station
- Ave. Duration
- 15h 10m
- Frequency
- Once daily
- Estimated price
- €80–120
- Website
- Flixbus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Florence Villa Constanza Bus Station to Karlsruhe Central Bus Station
- Ave. Duration
- 11h 15m
- Frequency
- Once a week
- Estimated price
- €110–160
- Website
- Onebus
Want to know more about travelling around Germany
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Booking & Getting There
Siena to Karlsruhe bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Siena to Karlsruhe train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Karlsruhe is 890 km. It takes approximately 8h 47m to drive from Siena to Karlsruhe.
Book your Siena to Karlsruhe train tickets online with Omio.
Book your Siena to Karlsruhe bus tickets online with Omio.
There are 894+ hotels available in Karlsruhe.























































