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How to get fromSiena to Kasselby train (Trenitalia), bus, train, night train, car, car train, or plane

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There are 13 ways to get from Siena to Kassel by train (Trenitalia), bus, train, night train, car, car train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    4. Take the train from Basel SBB to Kassel Bahnhof Wilhelmshöhetrain train 20 / ...
    14h 32m
    €212–629

  2. Train, night train

    cheapest
    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Bolzano Bozentrain train Fr
    3. Take the train from Bolzano Bozen to Brennero - Brennertrain train Re
    4. Take the night train from Innsbruck Hauptbahnhof to Kassel-Wilhelmshoehenighttrain night train Nj
    17h 33m
    €115–302

  3. Bus

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Nürnberg, Zobbus bus
    3. Take the bus from Nuremberg central bus station to Kasselbus bus N73
    15h 58m

  4. Drive 1,115.4 km

    1. Drive from Siena to Kasselcar car 1,115.4 km
    11h 21m
    €175–253

  5. Bus, train

    1. Take the bus from Siena Central Train Station to Milan Malpensa Terminal 2 Arrivalsbus bus
    2. Take the train from Malpensa Aeroporto T2 to Luganotrain train S50
    3. Take the train from Lugano to Frankfurttrain train Ec
    4. Take the train from Friedberg to Kassel Hauptbahnhoftrain train
    19h 56m
    €279–789

  6. Drive, car train

    1. Drive from Siena to Kufsteincar car
    2. Take the car train from Kufstein to Kassel-Wilhelmshöhecartrain train Uex 2026
    12h 23m
    €196–265

  7. Train to Florence Peretola Airport, fly to Düsseldorf International Airport, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Düsseldorf International Airport (DUS)plane plane FLR - DUS
    3. Take the train from Duesseldorf Flughafen to Kassel-Wilhelmshoehetrain train
    9h 35m
    €166–454

  8. Train to Florence Peretola Airport, fly to Frankfurt, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane plane FLR - FRA
    3. Take the train from Frankfurt to Fulda Bahnhoftrain train
    4. Take the train from Fulda Bahnhof to Kassel Bahnhof Wilhelmshöhetrain train
    8h 22m
    €170–446

  9. Train, train to Bologna Guglielmo Marconi Airport, fly to Frankfurt

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)plane plane BLQ - FRA
    4. Take the train from Frankfurt to Fulda Bahnhoftrain train
    5. Take the train from Fulda Bahnhof to Kassel Bahnhof Wilhelmshöhetrain train
    8h 43m
    €152–464

  10. Train, train to Pisa International Airport, fly to Frankfurt

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Frankfurt (FRA)plane plane PSA - FRA
    4. Take the train from Frankfurt to Fulda Bahnhoftrain train
    5. Take the train from Fulda Bahnhof to Kassel Bahnhof Wilhelmshöhetrain train
    8h 21m
    €154–405

  11. Train to Florence Peretola Airport, fly to Munich International Airport, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Munich International Airport (MUC)plane plane FLR - MUC
    3. Take the train from München Hbf to Kassel Bahnhof Wilhelmshöhetrain train
    10h 7m
    €221–633

  12. Train, train to Bologna Guglielmo Marconi Airport, fly to Cologne Bonn Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Cologne Bonn Airport (CGN)plane plane BLQ - CGN
    4. Take the train from Siegburg/Bonn to Frankfurt(Main)Hbftrain train
    5. Take the train from Frankfurt to Kassel Bahnhof Wilhelmshöhetrain train
    9h 57m
    €120–591

  13. Train, train to Pisa International Airport, fly to Cologne Bonn Airport

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Cologne Bonn Airport (CGN)plane plane PSA - CGN
    4. Take the train from Siegburg/Bonn to Frankfurt(Main)Hbftrain train
    5. Take the train from Frankfurt to Kassel Bahnhof Wilhelmshöhetrain train
    9h 35m
    €132–512

Siena to Kassel by train

Calendar72Weekly Trains
Duration14h 32mAverage Duration
Ticket€212Cheapest Price
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Questions & Answers

Map of how to get from Siena to Kassel.ExpandLaunch map view
  • Distance: 1,282.3 km
  • Duration: 14h 32m

What companies run services between Siena, Italy and Kassel, Germany?

You can take a train from Siena to Kassel Bahnhof Wilhelmshöhe via Firenze S.M.N., Milano Centrale, and Basel SBB in around 14h 32m. Alternatively, you can take a bus from Siena to Kassel via Florence Villa Constanza Bus Station and Nuremberg central bus station in around 15h 58m.

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