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How to get fromSiena to Madridby train, plane, train (Trenitalia, Renfe, Ouigo), bus, or car

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There are 9 ways to get from Siena to Madrid by train, plane, train (Trenitalia, Renfe, Ouigo), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane FLR - MAD
    6h 56m
    €75–174

  2. Train, train to Fiumicino International Airport, fly

    cheapest
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    3. Fly from Fiumicino International Airport (FCO) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane FCO - MAD
    8h 55m
    €74–229

  3. Train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Torino Porta Susatrain train Fr
    3. Take the train from Torino Porta Susa to Lyon Part Dieutrain train Fr
    4. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    5. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train
    19h 20m
    €247–514

  4. Bus via Genoa

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Genoabus bus 510 / ...
    3. Take the bus from Genoa to Madridbus bus
    26h 30m
    €143–260

  5. Drive 1,674.5 km

    1. Drive from Siena to Madridcar car 1,674.5 km
    17h 18m
    €265–383

  6. Train, train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane BLQ - MAD
    7h 17m
    €82–252

  7. Train, train to Pisa International Airport, fly

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane PSA - MAD
    6h 50m
    €79–213

  8. Bus, train

    1. Take the bus from Siena to Nice - Airport Bus Station Terminal 1bus bus
    2. Take the train from Antibes to Marseille-Saint-Charlestrain train
    3. Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain train
    21h 5m
    €227–434

  9. Bus

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131
    2. Take the bus from Florence to Padovabus bus
    3. Take the bus from Padova to Méndez Álvaro Estación Surbus bus
    33h 51m
    €150–195

Siena to Madrid by train

Calendar14Weekly Trains
Duration19h 20mAverage Duration
Ticket€247Cheapest Price
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Questions & Answers

Map of how to get from Siena to Madrid.ExpandLaunch map view
  • Distance: 1,380 km
  • Duration: 6h 56m

What companies run services between Siena, Italy and Madrid, Spain?

You can take a train from Siena to Madrid-Puerta de Atocha-Almudena Grandes via Firenze S.M.N., Torino Porta Susa, Lyon Part Dieu, and Barcelona-Sants in around 19h 20m. Alternatively, you can take a bus from Siena to Madrid via Florence Villa Constanza Bus Station and Genoa in around 26h 30m.

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