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How to get fromSiena to Madridby train, plane, train (Trenitalia, Renfe, Ouigo), bus, car, or train (Trenitalia, Renfe)

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There are 8 ways to get from Siena to Madrid by train, plane, train (Trenitalia, Renfe, Ouigo), bus, car, or train (Trenitalia, Renfe)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane FLR - MAD
    6h 47m
    €74–189
  2. Train, train to Pisa International Airport, fly

    cheapest
    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane PSA - MAD
    6h 57m
    €48–247
  3. Train via Barcelona

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Lyon Part Dieutrain train Fr
    4. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    5. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    18h 55m
    €216–435
  4. Bus

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Genoabus bus 510 / ...
    3. Take the bus from Genoa to Madridbus bus
    26h 30m
    €156–239
  5. Drive  1,674.5 km

    1. Drive from Siena to Madridcar car 1,674.5 km
    17h 18m
    €274–396
  6. Train, train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane BLQ - MAD
    7h 34m
    €71–277
  7. Train

    1. Take the train from Siena to Empolitrain train Re
    2. Take the train from Empoli to Pisa Centraletrain train Re
    3. Take the train from Pisa Centrale to Ventimigliatrain train Ic
    4. Take the train from Nice-Ville to Marseille-Saint-Charlestrain train
    5. Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain train
    21h 23m
    €247–380
  8. Bus, train

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131
    2. Take the train from Firenze S.M.N. to Padovatrain train Fr
    3. Take the bus from Padova to Méndez Álvaro Estación Surbus bus
    32h 27m
    €154–216

Siena to Madrid by train

Calendar7Weekly Trains
Duration18h 55mAverage Duration
Ticket€216Cheapest Price
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Comparing Your Travel Options

What companies run services between Siena, Italy and Madrid, Spain?

You can take a train from Siena to Madrid-Puerta de Atocha-Almudena Grandes via Firenze S.M.N., Milano Centrale, Lyon Part Dieu, and Barcelona-Sants in around 18h 55m. Alternatively, you can take a bus from Siena to Madrid via Florence Villa Constanza Bus Station and Genoa in around 26h 30m.

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