There are 10 ways to get from Siena to Messina by train, ferry, bus, car, plane, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, ferry (Trenitalia)
best- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
10h 37mBus
cheapest- Take the bus from Siena to Messinabus N597 / ...
11h 20m€45–120Drive, ferry
- Drive from Siena to Villa San Giovannicar
- Take the ferry from Villa San Giovanni to Messina Marittimaferry
8h 47m€147–212Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the train from Catania Centrale to Messina Centraletrain
7h 48m€48–216Train, car ferry
- Take the train from Siena to Chiusi-Chianciano T.train Re
- Take the train from Chiusi-Chianciano T. to Villa S.Giovannitrain Ic
- Take the carferry from Villa San Giovanni to Messina Marittimacarferry
13h 28m€92–275Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the bus from Florence Villa Constanza Bus Station to Messina Main Train Stationbus Itabus
16h 24m€57–148Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the train from Catania Centrale to Messina Centraletrain
8h 3m€65–244Train, train to Bologna Guglielmo Marconi Airport, fly to Catania–Fontanarossa Airport
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Catania–Fontanarossa Airport (CTA)plane BLQ - CTA
- Take the train from Catania Centrale to Messina Centraletrain
8h 35m€49–284Train to Florence Peretola Airport, fly to Palermo Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
- Take the train from Palermo Centrale to Messina Centraletrain
9h 39m€80–279Train, train to Pisa International Airport, fly to Palermo Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
- Take the train from Palermo Centrale to Messina Centraletrain
9h 49m€80–307
Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Siena to Messina is to bus which costs €45 - €120 and takes 11h 20m.
The fastest way to get from Siena to Messina is to train and fly which takes 7h 48m and costs €45 - €220.
Yes, there is a direct bus departing from Siena and arriving at Messina. Services depart twice daily, and operate every day. The journey takes approximately 11h 20m.
The distance between Siena and Messina is 993 km.
The best way to get from Siena to Messina without a car is to train and ferry which takes 10h 37m and costs .
It takes approximately 10h 37m to get from Siena to Messina, including transfers.
Siena to Messina bus services, operated by FlixBus, depart from Siena station.
Siena to Messina bus services, operated by FlixBus, arrive at Messina station.
Book your Siena to Messina bus tickets online with Omio and FlixBus.
There are 1160+ hotels available in Messina.
What companies run services between Siena, Italy and Messina, Italy?
FlixBus operates a bus from Siena to Messina once daily. Tickets cost €80–120 and the journey takes 11h 20m. Itabus S.p.A. also services this route once daily.
- Website
- ryanair.com
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €35–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 45m
- When
- Tuesday and Monday
- Estimated price
- €35–190
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €35–210
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 50m
- When
- Friday
- Estimated price
- €35–210
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–200
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- €90–190
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €85–210
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- €85–180
- Website
- volotea.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €16–110
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €90–190
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €85–210
Flights from Florence Peretola Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €18–130
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €85–180
- Website
- flyulendo.com
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €15–95
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €16–65
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €35–190
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Chiusi-Chianciano T.
- Ave. Duration
- 1h 28m
- Frequency
- Every 2 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Every 4 hours
- Estimated price
- €26–40
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Every 4 hours
- Estimated price
- €26–40
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Villa S.Giovanni
- Ave. Duration
- 6h 58m
- Frequency
- 3 times a day
- Estimated price
- €120–210
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Chiusi-Chianciano T. to Villa S.Giovanni
- Ave. Duration
- 10h 6m
- Frequency
- Once a week
- Estimated price
- €80–160
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- €23–45
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- €23–45
- Website
- Trenitalia Intercity
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 39 min
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Siena to Messina
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Estimated price
- €80–120
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Siena to Messina
- Ave. Duration
- 13h 20m
- Frequency
- Once daily
- Estimated price
- €45–85
- Website
- Itabus S.p.A.
Bus from Florence Villa Constanza Bus Station to Messina Main Train Station
- Ave. Duration
- 13h 45m
- Frequency
- Twice daily
- Estimated price
- €50–95
- Website
- Itabus S.p.A.
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Schedules at
- at-bus.it
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Florence Villa Constanza Bus Station to Messina Main Train Station
- Ave. Duration
- 14h 14m
- Frequency
- 3 times a week
- Estimated price
- €95–140
- Website
- Onebus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- 3409848540
- [email protected]
- Website
- blujetlines.it
Ferry from Villa San Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
- Phone
- +39.090.57.37
- [email protected]
- Website
- carontetourist.it
Car ferry from Villa San Giovanni to Messina Marittima
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €1–100
- Schedules at
- carontetourist.it
- Passenger
- €3
- Car
- €35–100
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