There are 6 ways to get from Siena to Milano Centrale Station by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Siena to Firenze S.M.N.train Re / ...
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
3h 47m€42–109Bus
cheapest- Take the bus from Siena to Milano, Autostazione Lampugnanobus N528 / ...
5h 49m€34–56Drive 363.3 km
- Drive from Siena to Milano Centrale Stationcar 363.3 km
3h 38m€57–82Train, fly to Milan Linate Airport
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Milan Linate Airport (LIN)plane FLR - LIN
6h 3m€116–296Bus via Florence
- Take the bus from Siena to Florence Villa Constanza Bus Stationbus 1509 / ...
- Take the bus from Florence Villa Constanza Bus Station to Milano - Famagostabus
5h 55mTrain, fly to Milano Malpensa Airport
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Milano Malpensa Airport (MXP)plane FLR - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Centraletrain
7h 18m€108–217
Siena to Milano Centrale Station by train
Questions & Answers
The cheapest way to get from Siena to Milano Centrale Station is to bus which costs €30 - €60 and takes 5h 49m.
The fastest way to get from Siena to Milano Centrale Station is to drive which takes 3h 38m and costs €55 - €85.
No, there is no direct bus from Siena to Milano Centrale Station. However, there are services departing from Siena and arriving at Milano, Autostazione Lampugnano via . The journey, including transfers, takes approximately 5h 49m.
No, there is no direct train from Siena to Milano Centrale Station. However, there are services departing from Siena and arriving at Milano Centrale via Firenze S.M.N.. The journey, including transfers, takes approximately 3h 47m.
The distance between Siena and Milano Centrale Station is 397 km. The road distance is 363.3 km.
The best way to get from Siena to Milano Centrale Station without a car is to train which takes 3h 47m and costs €40 - €110.
It takes approximately 3h 47m to get from Siena to Milano Centrale Station, including transfers.
Siena to Milano Centrale Station bus services, operated by FlixBus, depart from Siena station.
Siena to Milano Centrale Station train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Milano Centrale Station is to train which takes 3h 47m and costs €40 - €110. Alternatively, you can bus, which costs €30 - €60 and takes 5h 49m.
What companies run services between Siena, Italy and Milano Centrale Station, Italy?
You can take a train from Siena to Milano Centrale via Firenze S.M.N. in around 3h 47m. Alternatively, FlixBus operates a bus from Siena to Milano, Autostazione Lampugnano every 4 hours. Tickets cost €30–55 and the journey takes 5h 10m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Milan Linate Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €140–250
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €170–650
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- €110–700
Flights from Florence Peretola Airport to Milan Linate Airport via Vienna
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €100–390
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- €85–290
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- €140–550
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €170–650
Flights from Florence Peretola Airport to Milan Linate Airport via Rome
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- €140–250
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- €110–700
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- €140–550
- Website
- flexflight.dk
Flights from Florence Peretola Airport to Milan Linate Airport via Elba Island
- Ave. Duration
- 2h 30m
- When
- Friday
- Estimated price
- €40–550
Flights from Florence Peretola Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 4h 20m
- When
- Monday and Friday
- Estimated price
- €130–750
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Saturday
- Estimated price
- €170–650
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- €190–700
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- €140–550
- Website
- swiss.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- €85–290
- Website
- polarair.ru
Flights from Florence Peretola Airport to Milan Linate Airport via Elba Island
- Ave. Duration
- 2h 30m
- When
- Friday
- Estimated price
- €40–550
- Website
- aeroitalia.com
Flights from Florence Peretola Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 4h 20m
- When
- Monday and Friday
- Estimated price
- €130–750
- Website
- austrian.com
Flights from Florence Peretola Airport to Milan Linate Airport via Vienna
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €100–390
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €45–90
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 2h 37m
- Frequency
- 4 times a day
- Estimated price
- €35–80
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- 3 times a day
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Milano Centrale
- Ave. Duration
- 56 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Siena to Milano, Autostazione Lampugnano
- Ave. Duration
- 5h 10m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €5–10
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €5–11
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Florence Villa Constanza Bus Station to Milano - Famagosta
- Ave. Duration
- 2h 41m
- Frequency
- Once a week
- Website
- https://onebus.it/
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Siena to Milano Centrale Station bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Siena to Milano Centrale Station train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Milano Centrale Station is 363 km. It takes approximately 3h 38m to drive from Siena to Milano Centrale Station.
Book your Siena to Milano Centrale Station train tickets online with Omio.
There are 14402+ hotels available in Milano Centrale Station.






























