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How to get fromSiena to Nijmegenby train, plane, train (Trenitalia), bus, night train, car, or car train

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There are 13 ways to get from Siena to Nijmegen by train, plane, train (Trenitalia), bus, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly to Düsseldorf International Airport, train

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Düsseldorf International Airport (DUS)plane plane FLR - DUS
    3. Take the train from Duesseldorf Flughafen to Arnhem Centraaltrain train
    8h 9m
    €152–288

  2. Train, train to Pisa International Airport, fly to Eindhoven Airport

    cheapest
    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Eindhoven Airport (EIN)plane plane PSA - EIN
    4. Take the train from 's-Hertogenbosch to Nijmegentrain train
    7h 44m
    €86–336

  3. Train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    4. Take the train from Basel SBB to Frankfurttrain train 43 / ...
    5. Take the train from Frankfurt to Arnhem Centraaltrain train 78 / ...
    16h 39m
    €209–754

  4. Bus, train

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131
    2. Take the bus from Florence Villa Constanza Bus Station to Duesseldorf Worringer Straßebus bus
    3. Take the train from Düsseldorf Hbf to Kleve Bahnhoftrain train
    22h 25m
    €184–260

  5. Train, night train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Bolzano Bozentrain train Fr
    3. Take the train from Bolzano Bozen to Brennero - Brennertrain train Re
    4. Take the nighttrain from Innsbruck Hauptbahnhof to Arnhem Centraalnighttrain night train Nj
    21h 41m
    €132–327

  6. Train to Florence Peretola Airport, fly to Amsterdam Airport Schiphol, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Amsterdam Airport Schiphol (AMS)plane plane FLR - AMS
    3. Take the train from Schiphol Airport Train Station to Nijmegentrain train
    7h 54m
    €122–318

  7. Train to Florence Peretola Airport, fly to Brussels Airport, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Brussels Airport (BRU)plane plane FLR - BRU
    3. Take the train from Brussels Airport-Zaventem to Bredatrain train
    4. Take the train from Breda to Nijmegentrain train
    8h 52m
    €93–286

  8. Train, train to Bologna Guglielmo Marconi Airport, fly to Eindhoven Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Eindhoven Airport (EIN)plane plane BLQ - EIN
    4. Take the train from 's-Hertogenbosch to Nijmegentrain train
    8h 9m
    €100–386

  9. Train, train to Pisa International Airport, fly to Amsterdam Airport Schiphol

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Amsterdam Airport Schiphol (AMS)plane plane PSA - AMS
    4. Take the train from Schiphol Airport Train Station to Nijmegentrain train
    8h 2m
    €121–326

  10. Train to Florence Peretola Airport, fly to Frankfurt, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane plane FLR - FRA
    3. Take the train from Frankfurt to Arnhem Centraaltrain train
    9h 16m
    €171–556

  11. Bus

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Essen central train stationbus bus
    3. Take the bus from Essen central train station to Nijmegen Centraal Stationbus bus 037
    23h 45m
    €103–182

  12. Drive 1,313.3 km

    1. Drive from Siena to Nijmegencar car 1,313.3 km
    12h 45m
    €234–337

  13. Drive, car train

    1. Drive from Siena to Kufsteincar car
    2. Take the cartrain from Kufstein to Kassel-Wilhelmshöhecartrain train
    3. Drive from Kassel-Wilhelmshöhe to Nijmegencar car
    15h 22m
    €245–345

Siena to Nijmegen by train

Calendar68Weekly Trains
Duration16h 39mAverage Duration
Ticket€209Cheapest Price
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Questions & Answers

Map of how to get from Siena to Nijmegen.ExpandLaunch map view
  • Distance: 1,128.1 km
  • Duration: 8h 9m

What companies run services between Siena, Italy and Nijmegen, Netherlands?

You can take a train from Siena to Nijmegen via Firenze S.M.N., Milano Centrale, Basel SBB, Frankfurt, and Arnhem Centraal in around 16h 39m. Alternatively, you can take a bus from Siena to Nijmegen Centraal Station via Florence Villa Constanza Bus Station and Essen central train station in around 23h 45m.

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