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How to get fromSiena to Nijmegenby train, plane, train (Trenitalia), bus, night train, car, or car train

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There are 13 ways to get from Siena to Nijmegen by train, plane, train (Trenitalia), bus, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly to Düsseldorf International Airport, train

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Düsseldorf International Airport (DUS)plane plane FLR - DUS
    3. Take the train from Duesseldorf Flughafen to Arnhem Centraaltrain train
    8h 17m
    €157–288

  2. Train, train to Pisa International Airport, fly to Eindhoven Airport

    cheapest
    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Eindhoven Airport (EIN)plane plane PSA - EIN
    4. Take the train from 's-Hertogenbosch to Nijmegentrain train
    7h 39m
    €86–327

  3. Train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    4. Take the train from Basel SBB to Frankfurttrain train 43 / ...
    5. Take the train from Frankfurt to Arnhem Centraaltrain train 78 / ...
    16h 41m
    €214–764

  4. Bus, train

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131
    2. Take the bus from Florence Villa Constanza Bus Station to Duesseldorf Worringer Straßebus bus
    3. Take the train from Düsseldorf Hbf to Kleve Bahnhoftrain train
    22h 32m

  5. Train, night train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Bolzano Bozentrain train Fr
    3. Take the train from Bolzano Bozen to Brennero - Brennertrain train Re
    4. Take the night train from Innsbruck Hauptbahnhof to Arnhem Centraalnighttrain night train Nj
    21h 40m
    €132–327

  6. Train to Florence Peretola Airport, fly to Amsterdam Airport Schiphol, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Amsterdam Airport Schiphol (AMS)plane plane FLR - AMS
    3. Take the train from Schiphol Airport Train Station to Nijmegentrain train
    8h 8m
    €127–328

  7. Train, train to Bologna Guglielmo Marconi Airport, fly to Eindhoven Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Eindhoven Airport (EIN)plane plane BLQ - EIN
    4. Take the train from 's-Hertogenbosch to Nijmegentrain train
    8h 6m
    €99–346

  8. Train to Florence Peretola Airport, fly to Brussels Airport, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Brussels Airport (BRU)plane plane FLR - BRU
    3. Take the train from Brussels Airport-Zaventem to Bredatrain train
    4. Take the train from Breda to Nijmegentrain train
    8h 55m
    €93–286

  9. Train, train to Pisa International Airport, fly to Amsterdam Airport Schiphol

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Amsterdam Airport Schiphol (AMS)plane plane PSA - AMS
    4. Take the train from Schiphol Airport Train Station to Nijmegentrain train
    8h 2m
    €131–327

  10. Train to Florence Peretola Airport, fly to Frankfurt, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane plane FLR - FRA
    3. Take the train from Frankfurt to Arnhem Centraaltrain train
    9h 27m
    €171–556

  11. Bus

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Essen central train stationbus bus
    3. Take the bus from Essen central train station to Nijmegen Centraal Stationbus bus 037
    23h 45m
    €115–206

  12. Drive 1,313.3 km

    1. Drive from Siena to Nijmegencar car 1,313.3 km
    12h 45m
    €235–339

  13. Drive, car train

    1. Drive from Siena to Kufsteincar car
    2. Take the car train from Kufstein to Kassel-Wilhelmshöhecartrain train
    3. Drive from Kassel-Wilhelmshöhe to Nijmegencar car
    15h 22m
    €246–346

Siena to Nijmegen by train

Calendar68Weekly Trains
Duration16h 41mAverage Duration
Ticket€214Cheapest Price
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Questions & Answers

Map of how to get from Siena to Nijmegen.ExpandLaunch map view
  • Distance: 1,128 km
  • Duration: 8h 17m

What companies run services between Siena, Italy and Nijmegen, Netherlands?

You can take a train from Siena to Nijmegen via Firenze S.M.N., Milano Centrale, Basel SBB, Frankfurt, and Arnhem Centraal in around 16h 41m. Alternatively, you can take a bus from Siena to Nijmegen Centraal Station via Florence Villa Constanza Bus Station and Essen central train station in around 23h 45m.

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