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How to get fromSiena to Nijmegenby train, plane, train (Trenitalia), bus, night train, car, or car train

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There are 13 ways to get from Siena to Nijmegen by train, plane, train (Trenitalia), bus, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly to Amsterdam Airport Schiphol, train

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Amsterdam Airport Schiphol (AMS)plane plane FLR - AMS
    3. Take the train from Schiphol Airport Train Station to Nijmegentrain train
    7h 55m
    €126–282

  2. Train, train to Pisa International Airport, fly to Eindhoven Airport

    cheapest
    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Eindhoven Airport (EIN)plane plane PSA - EIN
    4. Take the train from 's-Hertogenbosch to Nijmegentrain train
    8h 2m
    €86–317

  3. Train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Frankfurt(Main)Hbftrain train Ec
    4. Take the train from Frankfurt to Arnhem Centraaltrain train 78
    16h 53m
    €228–424

  4. Bus, train

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131
    2. Take the bus from Florence Villa Constanza Bus Station to Duesseldorf Worringer Straßebus bus
    3. Take the train from Düsseldorf Hbf to Kleve Bahnhoftrain train
    22h 27m
    €176–295

  5. Train, night train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train Fr
    3. Take the nighttrain from Bologna Centrale to Innsbruck Hauptbahnhofnighttrain night train Nj
    4. Take the nighttrain from Innsbruck Hauptbahnhof to Arnhem Centraalnighttrain night train Nj
    22h 9m
    €100–329

  6. Train to Florence Peretola Airport, fly to Düsseldorf International Airport, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Düsseldorf International Airport (DUS)plane plane FLR - DUS
    3. Take the train from Duesseldorf Flughafen to Arnhem Centraaltrain train
    8h 15m
    €156–293

  7. Train to Florence Peretola Airport, fly to Brussels Airport, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Brussels Airport (BRU)plane plane FLR - BRU
    3. Take the train from Brussels Airport-Zaventem to Bredatrain train
    4. Take the train from Breda to Nijmegentrain train
    8h 39m
    €97–281

  8. Train, train to Bologna Guglielmo Marconi Airport, fly to Amsterdam Airport Schiphol

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Amsterdam Airport Schiphol (AMS)plane plane BLQ - AMS
    4. Take the train from Schiphol Airport Train Station to Nijmegentrain train
    8h 31m
    €123–360

  9. Train, train to Bologna Guglielmo Marconi Airport, fly to Eindhoven Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Eindhoven Airport (EIN)plane plane BLQ - EIN
    4. Take the train from 's-Hertogenbosch to Nijmegentrain train
    8h 19m
    €93–387

  10. Train to Florence Peretola Airport, fly to Frankfurt, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane plane FLR - FRA
    3. Take the train from Frankfurt to Arnhem Centraaltrain train
    9h 13m
    €170–451

  11. Bus

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Essen central train stationbus bus
    3. Take the bus from Essen central train station to Nijmegen Centraal Stationbus bus 037
    23h 45m
    €125–194

  12. Drive  1,313.3 km

    1. Drive from Siena to Nijmegencar car 1,313.3 km
    12h 46m
    €243–350

  13. Drive, car train

    1. Drive from Siena to Villach Hbfcar car
    2. Take the cartrain from Villach Hbf to Fuldacartrain train
    3. Drive from Fulda to Nijmegencar car
    18h 35m
    €255–359

Siena to Nijmegen by train

Calendar7Weekly Trains
Duration16h 53mAverage Duration
Ticket€228Cheapest Price
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Comparing Your Travel Options

Map of how to get from Siena to Nijmegen.ExpandLaunch map view
  • Distance: 1,276.3 km
  • Duration: 7h 55m

What companies run services between Siena, Italy and Nijmegen, Netherlands?

You can take a train from Siena to Nijmegen via Firenze S.M.N., Milano Centrale, Frankfurt(Main)Hbf, Frankfurt, and Arnhem Centraal in around 16h 53m. Alternatively, you can take a bus from Siena to Nijmegen Centraal Station via Florence Villa Constanza Bus Station and Essen central train station in around 23h 45m.

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