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How to get fromSiena to Palermoby train, plane, ferry, bus, train (Trenitalia), car, or car ferry

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There are 10 ways to get from Siena to Palermo by train, plane, ferry, bus, train (Trenitalia), car, or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane plane FLR - PMO
    5h 24m
    €77–198

  2. Train, train to Bologna Guglielmo Marconi Airport, fly

    cheapest
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Palermo Airport (PMO)plane plane BLQ - PMO
    5h 55m
    €47–256

  3. Train, ferry

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Napoli Centraletrain train Fr
    3. Take the ferry from Naples Beverello to Port of Palermoferry ferry
    13h 33m
    €98–213

  4. Bus

    1. Take the bus from Siena to Palermobus bus N597
    16h
    €100–170

  5. Train (Trenitalia)

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    3. Take the train from Roma Termini to Palermo Centraletrain train Ic
    16h 2m
    €130–289

  6. Train, train to Pisa International Airport, fly

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane plane PSA - PMO
    5h 18m
    €49–217

  7. Bus to Perugia Sant'Egidio Airport, fly

    1. Take the bus from Siena to Perugiabus bus
    2. Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane plane PEG - PMO
    6h 20m
    €64–225

  8. Drive, car ferry

    1. Drive from Siena to Civitavecchia Portcar car
    2. Take the car ferry from Civitavecchia Port to Palermo Portocarferry car ferry
    15h 44m
    €84–127

  9. Train via Chiusi (Trenitalia)

    1. Take the train from Siena to Chiusi-Chianciano T.train train Re
    2. Take the train from Chiusi-Chianciano T. to Roma Terminitrain train Re
    3. Take the train from Roma Termini to Palermo Centraletrain train Ic
    17h 17m
    €118–245

  10. Bus via Florence

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131R / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus bus
    22h 26m

Siena to Palermo by train, subway, and ferry

Calendar6Weekly Services
Duration13h 33mAverage Duration
Ticket€98Cheapest Price
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Questions & Answers

Map of how to get from Siena to Palermo.ExpandLaunch map view
  • Distance: 773.5 km
  • Duration: 5h 24m

What companies run services between Siena, Italy and Palermo, Italy?

FlixBus operates a bus from Siena to Palermo once daily. Tickets cost €100–170 and the journey takes 16h. Alternatively, you can take a train from Siena to Palermo Centrale via Firenze S.M.N. and Roma Termini in around 16h 2m.

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