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How to get fromSiena to Pragueby train, plane, train (Trenitalia), bus, night train, or car

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There are 8 ways to get from Siena to Prague by train, plane, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Václav Havel Airport Prague (PRG)plane plane FLR - PRG
    6h 4m
    Kč 2,172–6,992

  2. Bus via Florence

    cheapest
    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131R / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Prague Florenc Central Bus Stationbus bus : Prague Central Bus Station - Rome Tiburtina Bus Station / ...
    19h 4m
    Kč 1,860–3,086

  3. Train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Venezia Mestretrain train Fr
    3. Take the train from Venezia Mestre to Wien Hbftrain train Rjx / ...
    4. Take the train from Wien Hbf to Praha Hlavni Nadrazitrain train Rj / ...
    17h 42m
    Kč 3,742–7,170

  4. Train, night train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the nighttrain from Firenze Campo Marte to Linz/Donau Hbfnighttrain night train En
    3. Take the train from Linz/Donau Hbf to Praha Hlavni Nadrazitrain train Ec
    19h 7m
    Kč 5,184–7,787

  5. Train, train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Václav Havel Airport Prague (PRG)plane plane BLQ - PRG
    6h 40m
    Kč 2,070–7,650

  6. Train, train to Pisa International Airport, fly

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Václav Havel Airport Prague (PRG)plane plane PSA - PRG
    6h 24m
    Kč 1,992–6,679

  7. Bus

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 1509 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Praha, ÚAN Florencbus bus N1533 / ...
    19h 20m
    Kč 2,541–3,808

  8. Drive  1,014.4 km

    1. Drive from Siena to Praguecar car 1,014.4 km
    11h 11m
    Kč 3,999–5,776

Siena to Prague by train

Calendar15Weekly Trains
Duration17h 42mAverage Duration
TicketKč 3,742Cheapest Price
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Comparing Your Travel Options

Map of how to get from Siena to Prague.ExpandLaunch map view
  • Distance: 852 km
  • Duration: 6h 4m

What companies run services between Siena, Italy and Prague, Czechia?

You can take a train from Siena to Praha Hlavni Nadrazi via Firenze S.M.N., Venezia Mestre, and Wien Hbf in around 17h 42m. Alternatively, you can take a bus from Siena-Via Tozzi to Prague Florenc Central Bus Station via Firenze Autostazione, Alamanni - Stazione Smn, Villa Costanza, and Florence Villa Constanza Bus Station in around 19h 4m.

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