There are 9 ways to get from Siena to San Sebastián de los Reyes by train, plane, train (Trenitalia, Renfe, Ouigo), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly
best- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane FLR - MAD
7h 17m€75–182Train, train to Pisa International Airport, fly
cheapest- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane PSA - MAD
7h 21m€50–250Train
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Barcelona-Santstrain
- Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain Ave
19h 14m€217–449Bus
- Take the bus from Siena to Florence Villa Constanza Bus Stationbus 443 / ...
- Take the bus from Florence to Barcelonabus
- Take the bus from Barcelona, Estació d'Autobusos Nord to Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)bus
25h 2m€147–230Drive 1,670 km
- Drive from Siena to San Sebastián de los Reyescar 1,670 km
17h 12m€273–394Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane BLQ - MAD
7h 56m€72–280Train, train to Fiumicino International Airport, fly
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane FCO - MAD
9h 10m€72–241Train, bus
- Take the train from Siena to Firenze S.M.N.train Re
- Take the bus from Florence to Marseille, Gare de Marseille-Saint-Charlesbus
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
21h 58m€207–314Bus, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Firenze S.M.N. to Padovatrain Fr
- Take the bus from Padova to Méndez Álvaro Estación Surbus
33h€156–222
Siena to San Sebastián de los Reyes by train
Comparing Your Travel Options
The cheapest way to get from Siena to San Sebastián de los Reyes is to train and fly which costs €75 - €190 and takes 7h 17m.
The fastest way to get from Siena to San Sebastián de los Reyes is to train and fly which takes 7h 17m and costs €75 - €190.
No, there is no direct bus from Siena to San Sebastián de los Reyes. However, there are services departing from Siena and arriving at Av.España-M.Sebastián Izuel via Florence, Barcelona, Estació d'Autobusos Nord and Av.Hispanidad-Aeropuerto T4. The journey, including transfers, takes approximately 25h 2m.
No, there is no direct train from Siena to San Sebastián de los Reyes. However, there are services departing from Siena and arriving at Alcobendas-San Sebastián de los Reyes via Firenze S.M.N., Milano Centrale, Lyon Part Dieu, Barcelona-Sants and Madrid-Atocha Cercanías. The journey, including transfers, takes approximately 19h 14m.
The distance between Siena and San Sebastián de los Reyes is 1396 km. The road distance is 1670 km.
The best way to get from Siena to San Sebastián de los Reyes without a car is to train which takes 19h 14m and costs €210 - €450.
It takes approximately 7h 17m to get from Siena to San Sebastián de los Reyes, including transfers.
Siena to San Sebastián de los Reyes bus services, operated by FlixBus, depart from Siena station.
Siena to San Sebastián de los Reyes train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to San Sebastián de los Reyes is to train which takes 19h 14m and costs €210 - €450. Alternatively, you can bus, which costs €140 - €230 and takes 25h 2m.
What companies run services between Siena, Italy and San Sebastián de los Reyes, Spain?
You can take a train from Siena to Alcobendas-San Sebastián de los Reyes via Firenze S.M.N., Milano Centrale, Lyon Part Dieu, Barcelona-Sants, Madrid-Puerta De Atocha-Almudena Grandes, and Madrid-Atocha Cercanías in around 19h 14m. Alternatively, you can take a bus from Siena to Av.España-M.Sebastián Izuel via Florence, Barcelona, Barcelona, Estació d'Autobusos Nord, Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid), and Av.Hispanidad-Aeropuerto T4 in around 25h 2m.
- Website
- iberia.com
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 28m
- When
- Every day
- Estimated price
- €60–200
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 12m
- When
- Sunday and Thursday
- Estimated price
- €60–150
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 33m
- When
- Every day
- Estimated price
- €50–160
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 40m
- When
- Monday
- Estimated price
- €45–170
Flights from Fiumicino International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- €40–140
- Website
- ryanair.com
Flights from Pisa International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Thursday, and Sunday
- Estimated price
- €60–220
Flights from Pisa International Airport to Adolfo Suárez Madrid–Barajas Airport via Palma Mallorca
- Ave. Duration
- 4h 17m
- When
- Friday and Wednesday
- Estimated price
- €60–220
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 30m
- When
- Tuesday, Friday, Sunday, Monday, and Wednesday
- Estimated price
- €45–170
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport via Ibiza
- Ave. Duration
- 4h 10m
- When
- Friday
- Estimated price
- €45–170
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport via Palma Mallorca
- Ave. Duration
- 4h 30m
- When
- Friday
- Estimated price
- €45–170
Flights from Fiumicino International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 37m
- When
- Every day
- Estimated price
- €55–190
Flights from Fiumicino International Airport to Adolfo Suárez Madrid–Barajas Airport via Palma Mallorca
- Ave. Duration
- 5h 35m
- When
- Tuesday
- Estimated price
- €55–190
- Website
- vueling.com
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 28m
- When
- Every day
- Estimated price
- €60–200
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 12m
- When
- Sunday and Thursday
- Estimated price
- €60–150
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 33m
- When
- Every day
- Estimated price
- €50–160
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 40m
- When
- Monday
- Estimated price
- €45–170
Flights from Fiumicino International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- €40–140
- Website
- aireuropa.com
Flights from Fiumicino International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 36m
- When
- Every day
- Estimated price
- €55–180
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 36m
- When
- Every day
- Estimated price
- €55–180
- Website
- flyulendo.com
Flights from Pisa International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €14–120
Flights from Fiumicino International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 33m
- When
- Every day
- Estimated price
- €25–140
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 43m
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Padova
- Ave. Duration
- 1h 44m
- Frequency
- Hourly
- Estimated price
- €29–50
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 39 min
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Lyon Part Dieu to Barcelona-Sants
- Ave. Duration
- 4h 48m
- Frequency
- Twice daily
- Estimated price
- €80–120
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 28m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 8h 14m
- Frequency
- Twice daily
- Estimated price
- €140–210
- Website
- Renfe Viajeros
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 23m
- Frequency
- Hourly
- Estimated price
- €55–95
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 32m
- Frequency
- Hourly
- Estimated price
- €45–80
- Website
- Ouigo
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Florence to Barcelona
- Ave. Duration
- 14h 15m
- Frequency
- Twice daily
- Estimated price
- €90–140
- Website
- Flixbus
Bus from Florence to Marseille, Gare de Marseille-Saint-Charles
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- €55–85
- Website
- Flixbus
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Barcelona, Estació d'Autobusos Nord to Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
- Ave. Duration
- 7h 35m
- Frequency
- Every 3 hours
- Estimated price
- €50–80
- Website
- ALSA
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Schedules at
- at-bus.it
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Padova to Méndez Álvaro Estación Sur
- Ave. Duration
- 27h 35m
- Frequency
- Once a week
- Estimated price
- €120–160
- Schedules at
- tabitatour.ro
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Booking & Getting There
Siena to San Sebastián de los Reyes bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Siena to San Sebastián de los Reyes train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to San Sebastián de los Reyes is 1670 km. It takes approximately 17h 12m to drive from Siena to San Sebastián de los Reyes.
Book your Siena to San Sebastián de los Reyes train tickets online with Omio.
There are 7034+ hotels available in San Sebastián de los Reyes.












































